General description
This reference presents recent breakthroughs and techniques in affinity capillary electrophoresis (ACE) to measure and determine the physicochemical and thermodynamic parameters of drug compounds—offering strategies to explore and characterize interactions between drugs, drug vehicles, and biological membranes to facilitate developments in controlled drug delivery and targeting. This book contains current applications and procedures to identify binding constants between drugs, biological structures, proteins, nucleic acids, and plasmids; increase drug bioavailability; enhance the permeability, solubility, strength, and function of drug formulations; examine protein-protein exchanges and reactions; calculate pKa values.