Drug Discovery for Nervous System Diseases 

The neurosciences have been a difficult field for drug discovery, but enormous progress in molecular biology has yielded breakthrough discoveries of the causes of nervous system diseases leading to better-targeted therapies. This book presents the latest techniques and approaches for drug discovery, organizing them according to diseases rather than classes of drugs or drug targets, as past books have done. The coverage includes: * Fundamentals of drug discovery-receptors, target selection, and drug development * Schizophrenia * Depression * Alzheimer's disease * Parkinson's disease * Ischemic stroke, brain, and spinal cord injury. Each chapter contains a description of existing drugs leading to recent molecular biological and genetic findings, translational research and the interface to clinical trials, and an outlook on future drug targets.