| Z718904 Sigma |
Mendel’s Legacy: The Origin of Classical Genetics |
General description
This latest book by Elof Carlson (The Unfit)is a first history of classical genetics, the era in which the chromosome theory of heredity was proposed and developed. Highly illustrated and based heavily on early 20th century original sources, the book traces the roots of genetics in breeding analysis and studies of cytology, evolution, and reproductive biology that began in Europe but were synthesized in the United States through new Ph.D. programs and expanded academic funding. Carlson argues that, influenced largely by new technologies and instrumentation, the life sciences progressed though incremental change rather than paradigm shifts, and he describes how molecular biology emerged from the key ideas and model systems of classical genetics. Readable and original, this narrative will interest historians and science educators as well as today's practitioners of genetics.
Table of Contents
Introduction
Chapter 1 Building a Body: Interleaving of Growth, Patterning, and Cell Proliferation during Multicellular Development
Chapter 2 Linkages Between Cell Growth and Cell–cycle Progression During Development
Chapter 3 Coordination of Cell Growth and Cell–cycle Progression in Proliferating Mammalian Cells
Chapter 4 Integration of Growth with the Cell Cycle
Chapter 5 TOR Signaling in Yeast: Temporal and Spatial Control of Cell Growth
Chapter 6 TOR and Insulin Signaling in Drosophila
Chapter 7 mTOR and Control of Cell Growth in Response to Nutrients
Chapter 8 IGF–I Receptor Signaling in Cell Growth
Chapter 9 S6 Kinase and Cell Growth
Chapter 10 Control of Cell Growth via Translation Initiation
Chapter 11 Synaptic Growth, Synaptic Maintenance, and Long-term Memory Storage
Chapter 12 The Control of Synaptic Function by Local Protein Synthesis and Degradation
Chapter 13 Forging the Factory: Ribosome Synthesis and Growth Control in Budding Yeast
Chapter 14 Control of rRNA and tRNA Production Is Closely Tied to Cell Growth and Biosynthetic Capacity
Chapter 15 Cellular Recycling System: Molecular Mechanism of Autophagy
Chapter 16 Plant Cell Growth in the Solid State
Chapter 17 Genetic Analysis of Growth Regulation in the Drosophila Eye
Chapter 18 Lymphocyte Growth
Chapter 19 Control of Skeletal Muscle Mass
Chapter 20 The Mechanism of Control of the Heart Size in Mammals
Chapter 21 Regulation of Cell Growth in the Endocrine Pancreas
Chapter 1 Building a Body: Interleaving of Growth, Patterning, and Cell Proliferation during Multicellular Development
Chapter 2 Linkages Between Cell Growth and Cell–cycle Progression During Development
Chapter 3 Coordination of Cell Growth and Cell–cycle Progression in Proliferating Mammalian Cells
Chapter 4 Integration of Growth with the Cell Cycle
Chapter 5 TOR Signaling in Yeast: Temporal and Spatial Control of Cell Growth
Chapter 6 TOR and Insulin Signaling in Drosophila
Chapter 7 mTOR and Control of Cell Growth in Response to Nutrients
Chapter 8 IGF–I Receptor Signaling in Cell Growth
Chapter 9 S6 Kinase and Cell Growth
Chapter 10 Control of Cell Growth via Translation Initiation
Chapter 11 Synaptic Growth, Synaptic Maintenance, and Long-term Memory Storage
Chapter 12 The Control of Synaptic Function by Local Protein Synthesis and Degradation
Chapter 13 Forging the Factory: Ribosome Synthesis and Growth Control in Budding Yeast
Chapter 14 Control of rRNA and tRNA Production Is Closely Tied to Cell Growth and Biosynthetic Capacity
Chapter 15 Cellular Recycling System: Molecular Mechanism of Autophagy
Chapter 16 Plant Cell Growth in the Solid State
Chapter 17 Genetic Analysis of Growth Regulation in the Drosophila Eye
Chapter 18 Lymphocyte Growth
Chapter 19 Control of Skeletal Muscle Mass
Chapter 20 The Mechanism of Control of the Heart Size in Mammals
Chapter 21 Regulation of Cell Growth in the Endocrine Pancreas
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