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General description
Cell Signalling presents a carefully structured introduction to this intricate subject, introducing those conserved features which underlie many different extra-and intracellular signalling systems. Starting with an overview of cell signalling, which highlights its importance in many biological systems, the book goes on to explore the key components of extracellular and intracellular signalling mechanisms, before examining how these components come together to create the signalling pathways, which are so crucial to the survival of all living organisms.
Table of Contents
1. Aspects of Cell Signalling
2. Extracellular Signals - Hormones, Cytokines, Growth Factors 3. Detection of Extracellular Signals: The Role of Receptors 4. Protein Phosphorylation, Kinases and Phosphatases 5. Cyclic Nucleotides, Cyclases and G Proteins 6. Inositol Phosphate Metabolism and Roles of Membrane Lipids 7. Intracellular Calcium: Its Control and Role as an Intracellular Signal 8. Reactive Oxygen Species, Reactive Nitrogen Species and Redox Signalling 9. Insulin and the Signal Transduction Cascades it Invokes 10. Perception of the Environment 11. Life, death, and Apoptosis 12. Cell Signalling: Importance, Complexity and Future
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