ADCY2 adenylate cyclase 2 (brain)

Activation of PKA through GPCR; Alpha-Adrenergic Signaling; Beta-Adrenergic Signaling; CDK5 Pathway; CREB Pathway; ERK Signaling; GHRH Signaling; GPCR Pathway; Integrin Pathway; Intracellular Calcium Signaling; P2Y Receptor Signaling; PPAR Pathway; cAMP Pathway; Activation of cAMP-Dependent PKA; BAD Phosphorylation; CRHR Pathway; Dopamine-DARPP32 Feedback onto cAMP Pathway; GnRH Signaling; H. pylori Activated Signaling; Hedgehog Signaling in Mammals; IL-1 Pathway; Melanocyte Development and Pigmentation; NFAT and Cardiac Hypertrophy; PACAP Signaling; Relaxin Pathway; Renin-Angiotensin Pathway; S-1P Stimulated Signaling; Signaling Involved in Cardiac Hypertrophy; Sweet Taste Signaling; Thrombin Signaling through PARs; eNOS Signaling;
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Gene and Product Information
ADCY2	adenylate cyclase 2 (brain)

Properties

Official Symbol

ADCY2

Species

Homo sapiens

Entrez Gene ID

108

Alternate Symbol

ADCY2; FLJ16822; FLJ45092; HBAC2; KIAA1060; MGC133314

Other Designations

3',5'-cyclic AMP synthetase; ATP pyrophosphate-lyase; adenylate cyclase 2; adenylate cyclase II; adenylyl cyclase 2; type II adenylate cyclase

Refseq ID(s)

NM_020546

Accession No.(s)

AB028983; AF070583; AF410885; AK123013; AK127036; more...

Protein ID(s)

NP_065433

Homolog(s)

Adcy2(Mouse); Adcy2(Rat)

Pathway(s)

Activation of PKA through GPCR; Alpha-Adrenergic Signaling; Beta-Adrenergic Signaling; CDK5 Pathway; CREB Pathway; more...

Replaces Gene ID(s)

254679

Available Product(s)

siRNA, Antibodies, Small Molecule - Inhibitor, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
WH0000108M1	Monoclonal Anti-ADCY2 antibody produced in mouse clone 1D4, purified immunoglobulin, buffered aqueous solution	human

Small Molecule - Inhibitor

Product #	Description
S153	SQ 22,536 ≥98% (HPLC), solid

MISSION shRNA

Type	Description
SHGLY-NM_020546	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_020546	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_020546	MISSION^® shRNA Plasmid DNA

MISSION siRNA Panels

Product #	Description
SI00100	MISSION^® siRNA Human Druggable Genome Library 6650 targets
SI10100	MISSION^® siRNA Human Gene Family Panels Metabolism and Cell Traffic Panel, 217 targets

siRNA

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siRNA ID	RefSeq ID	Approx. siRNA Start	siRNA Type	Ranking
SASI_Hs01_00062565	NM_020546	3102	MISSION® siRNA	1
SASI_Hs01_00062566	NM_020546	2698	MISSION® siRNA	2
SASI_Hs01_00062567	NM_020546	1090	MISSION® siRNA	3
SASI_Hs01_00062568	NM_020546	1403	MISSION® siRNA	4
SASI_Hs01_00062569	NM_020546	477	MISSION® siRNA	5
SASI_Hs01_00062570	NM_020546	1086	MISSION® siRNA	6
SASI_Hs01_00062571	NM_020546	720	MISSION® siRNA	7
SASI_Hs01_00062572	NM_020546	2309	MISSION® siRNA	8
SASI_Hs01_00062573	NM_020546	940	MISSION® siRNA	9
SASI_Hs01_00062574	NM_020546	1873	MISSION® siRNA	10

Sigma's MISSION^® siRNA have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. Critical rules incorporated into the best-in-class Rosetta siRNA design algorithm lead to siRNA of increased target specificity and knockdown for low abundance messages.