EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

Gene and Product Information
EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

Properties

Official Symbol

EIF2S1

Species

Homo sapiens

Entrez Gene ID

1965

Alternate Symbol

EIF2S1; EIF-2; EIF-2A; EIF-2ALPHA; EIF2; EIF2A

Other Designations

eIF-2-alpha; eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD )

Refseq ID(s)

NM_004094

Accession No.(s)

BC002513; BX161521; CR598254; CR600389; CR601355; more...

Protein ID(s)

NP_004085

Homolog(s)

Eif2s1(Mouse); Eif2s1(Rat)

Function(s)

RNA binding; translation factor

Pathway(s)

GSK3 Signaling; PKR Pathway; eIF2 Pathway; Activation of NF-KappaB by PKR

Available Product(s)

siRNA, Antibodies, shRNA

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
E0157	Anti-eIF2α antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution	human
E2152	Anti-phospho-eIF-2α (pSer⁵²) antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution	human, rat, pig, yeast, mouse, bovine
WH0001965M1	Monoclonal Anti-EIF2S1 antibody produced in mouse clone 3H12-C11, purified immunoglobulin, buffered aqueous solution	human

MISSION shRNA

Type	Description
SHGLY-NM_004094	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_004094	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_004094	MISSION^® shRNA Plasmid DNA

siRNA

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siRNA ID	RefSeq ID	Approx. siRNA Start	siRNA Type	Ranking
SASI_Hs01_00155629	NM_004094	234	MISSION® siRNA	1
SASI_Hs01_00155630	NM_004094	777	MISSION® siRNA	2
SASI_Hs01_00155631	NM_004094	808	MISSION® siRNA	3
SASI_Hs01_00155632	NM_004094	357	MISSION® siRNA	4
SASI_Hs01_00155633	NM_004094	894	MISSION® siRNA	5
SASI_Hs01_00155634	NM_004094	335	MISSION® siRNA	6
SASI_Hs01_00155635	NM_004094	1143	MISSION® siRNA	7
SASI_Hs01_00155636	NM_004094	1093	MISSION® siRNA	8
SASI_Hs01_00155637	NM_004094	1095	MISSION® siRNA	9
SASI_Hs01_00155638	NM_004094	344	MISSION® siRNA	10

Sigma's MISSION^® siRNA have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. Critical rules incorporated into the best-in-class Rosetta siRNA design algorithm lead to siRNA of increased target specificity and knockdown for low abundance messages.