ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Akt Signaling; EGF Pathway; ERK Signaling; ErbB Family Pathway; GPCR Pathway; GSK3 Signaling; Intracellular Calcium Signaling; JNK Pathway; Molecular Mechanisms of Cancer; P2Y Receptor Signaling; PI3K Signaling; Paxillin Interactions; Rap1 Pathway; Ras Pathway; p38 Signaling; 14-3-3 Induced Intracellular Signaling; Actin Nucleation and Branching; Actin Nucleation by ARP-WASP Complex; Activation of cAMP-Dependent PKA; Agrin Interaction at Neuromuscular Junction; Alzheimers Disease Pathway; Endothelin-1 Signaling Pathway; ErbB2-ErbB3 Heterodimers; ErbB4 Pathway; Estrogen Pathway; Mucosal Healing through Trefoil Factors; NFAT in Immune Response; Signaling Involved in Cardiac Hypertrophy; Tec Kinases Signaling; Yersinia Infection; eNOS Signaling;
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Gene and Product Information
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Properties

Official Symbol

ERBB2

Species

Homo sapiens

Entrez Gene ID

2064

Alternate Symbol

ERBB2; C-ERB B2; HER-2; HER-2/NEU; HER2; NEU; NGL; TKR1

Other Designations

c-erb B2/neu protein; erbB-2; herstatin; neuroblastoma/glioblastoma derived oncogene homolog; tyrosine kinase-type cell surface receptor; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog)

Refseq ID(s)

NM_001005862; NM_004448

Accession No.(s)

AB025286; AF177761; AK131568; BC080193; BC110392; more...

Protein ID(s)

NP_001005862; NP_004439

Homolog(s)

Erbb2(Mouse); Erbb2(Rat)

Function(s)

electron carrier; growth factor/ligand/cytokine/chemokine receptor; protein kinase; signal transducer; transferase

Pathway(s)

Akt Signaling; EGF Pathway; ERK Signaling; ErbB Family Pathway; GPCR Pathway; more...

Available Product(s)

siRNA, Antibody Arrays, Antibodies, Small Molecule - Inhibitor, MISSION shRNA Panels, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
HPA001383	Anti-ERBB2 antibody produced in rabbit Ab1, Prestige Antibodies^™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	human
HPA007983	Anti-ERBB2 antibody produced in rabbit Ab2, Prestige Antibodies^™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	human
E8030	Anti-phospho-ErbB-2 (pTyr¹¹³⁹) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution	human, hamster, canine
E7780	Anti-phospho-ErbB-2 (pTyr¹²⁴⁸) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution	human, mammals
E2777	Monoclonal Anti-c-erbB-2 antibody produced in mouse ~2 mg/mL, clone HER2-96, purified immunoglobulin, buffered aqueous solution	human

Small Molecule - Inhibitor

Product #	Description
A9251	Adenosine ≥99%
A4036	Adenosine cell culture tested
G0668	GW2974 >99% (HPLC), solid
L2400	Lavendustin A ~85% (TLC), crystalline
T2067	Tyrphostin AG 879 99% (HPLC)

MISSION shRNA

Type	Description
SHGLY-NM_004448	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_004448	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_004448	MISSION^® shRNA Plasmid DNA

MISSION shRNA Panels

Product #

Description