FGF2 fibroblast growth factor 2 (basic)

Activation of PKA through GPCR; Akt Signaling; CREB Pathway; ERK Signaling; FGF Pathway; GPCR Pathway; GSK3 Signaling; IP3 Pathway; Intracellular Calcium Signaling; JNK Pathway; MAPK Family Pathway; Molecular Mechanisms of Cancer; P2Y Receptor Signaling; PAK Pathway; PI3K Signaling; PPAR Pathway; PTEN Pathway; Paxillin Interactions; Rap1 Pathway; Ras Pathway; SOCS Pathway; cAMP Pathway; eIF2 Pathway; mTOR Pathway; p38 Signaling; p70S6K Signaling; 14-3-3 Induced Intracellular Signaling; Actin-Based Motility by Rho Family GTPases; Activation of cAMP-Dependent PKA; Apoptotic Pathways in Synovial Fibroblasts; Cellular Apoptosis Pathway; Mitochondrial Apoptosis; NF-KappaB Family Pathway; NFAT in Immune Response; Nuclear Receptor Activation by Vitamin-A; Regulation of eIF4 and p70S6K; Renin-Angiotensin Pathway; RhoGDI Pathway; TGF-Beta Pathway; Tec Kinases Signaling; Telomerase Components in Cell Signaling; eNOS Signaling;
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Gene and Product Information
FGF2	fibroblast growth factor 2 (basic)

Properties

Official Symbol

FGF2

Species

Homo sapiens

Entrez Gene ID

2247

Alternate Symbol

FGF2; BFGF; FGFB; HBGH-2

Refseq ID(s)

NM_002006

Other Designations

basic fibroblast growth factor; basic fibroblast growth factor bFGF; fibroblast growth factor 2; heparin-binding growth factor 2 precusor; prostatropin

Accession No.(s)

AY820133; BC111737; BE439775; J04513; M17599; more...

Protein ID(s)

NP_001997

Homolog(s)

Fgf2(Mouse); Fgf2(Rat)

Function(s)

growth factor/ligand/cytokine/chemokine; protein binding

Pathway(s)

Activation of PKA through GPCR; Akt Signaling; CREB Pathway; ERK Signaling; FGF Pathway; more...

Available Product(s)

siRNA, Antibodies, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
F3393	Anti-Fibroblast Growth Factor-Basic (1-24) antibody produced in rabbit fractionated antiserum, lyophilized powder	bovine, rat, human
F5180	Anti-Fibroblast Growth Factor-Basic antibody produced in goat affinity isolated antibody, lyophilized powder	human, bovine
F5537	Anti-Fibroblast Growth Factor-Basic antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution	human
F5305	Monoclonal Anti-Fibroblast Growth Factor-Basic antibody produced in mouse clone 10060, purified immunoglobulin, lyophilized powder	human
F6162	Monoclonal Anti-Fibroblast Growth Factor-Basic antibody produced in mouse clone FB-8, purified immunoglobulin, buffered aqueous solution	human, bovine

MISSION shRNA

Type	Description
SHGLY-NM_002006	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_002006	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_002006	MISSION^® shRNA Plasmid DNA

MISSION siRNA Panels

Product #	Description
SI00100	MISSION^® siRNA Human Druggable Genome Library 6650 targets
SI04100	MISSION^® siRNA Human Gene Family Panels Human Growth Factors/Receptors Panel, 375 targets

siRNA

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siRNA ID	RefSeq ID	Approx. siRNA Start	siRNA Type	Ranking
SASI_Hs01_00230118	NM_002006	1022	MISSION® siRNA	1
SASI_Hs01_00230119	NM_002006	1025	MISSION® siRNA	2
SASI_Hs01_00230120	NM_002006	735	MISSION® siRNA	3
SASI_Hs01_00230121	NM_002006	727	MISSION® siRNA	4
SASI_Hs01_00230122	NM_002006	1035	MISSION® siRNA	5
SASI_Hs01_00230123	NM_002006	950	MISSION® siRNA	6
SASI_Hs01_00230124	NM_002006	856	MISSION® siRNA	7
SASI_Hs01_00230125	NM_002006	970	MISSION® siRNA	8
SASI_Hs01_00230126	NM_002006	787