GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2

Activation of PKA through GPCR; Akt Signaling; Alpha-Adrenergic Signaling; Beta-Adrenergic Signaling; CDK5 Pathway; CREB Pathway; ERK Signaling; GHRH Signaling; GPCR Pathway; IP3 Pathway; Intracellular Calcium Signaling; Melatonin Signaling; P2Y Receptor Signaling; PI3K Signaling; WNT Signaling; cAMP Pathway; p70S6K Signaling; AMPK Enzyme Complex Pathway; Actin Nucleation and Branching; Actin Nucleation by ARP-WASP Complex; Actin-Based Motility by Rho Family GTPases; Activation of cAMP-Dependent PKA; Androgen Signaling; Antiproliferative Role of SSTR2; CRHR Pathway; CXCR4 Pathway; Dopamine-DARPP32 Feedback onto cAMP Pathway; Endothelin-1 Signaling Pathway; EphB-EphrinB Signaling; Estrogen Pathway; GnRH Signaling; Hedgehog Signaling in Mammals; Huntington Disease Pathway; NFAT and Cardiac Hypertrophy; NgRp75(NTR)-Mediated Signaling; S-1P Stimulated Signaling; Signaling Involved in Cardiac Hypertrophy; Thrombin Signaling through PARs; Visual Cycle in Retinal Rods; eNOS Signaling; fMLP Pathway;
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Gene and Product Information
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2

Properties

Official Symbol

GNAI2

Species

Homo sapiens

Entrez Gene ID

2771

Alternate Symbol

GNAI2; GIP; GNAI2B; H_LUCA15.1; H_LUCA16.1

Refseq ID(s)

NM_002070

Other Designations

GTP-binding regulatory protein Gi alpha-2 chain; WUGSC:H_LUCA15.1; WUGSC:H_LUCA16.1; match to P04899 (PID:g121023)

Accession No.(s)

AF493906; AK055574; AK096299; AK096595; AK126708; more...

Protein ID(s)

NP_002061

Homolog(s)

Gnai2(Mouse); Gnai2(Rat)

Function(s)

GTPase; signal transducer

Pathway(s)

Activation of PKA through GPCR; Akt Signaling; Alpha-Adrenergic Signaling; Beta-Adrenergic Signaling; CDK5 Pathway; more...

Available Product(s)

siRNA, Antibodies, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
HPA007704	Anti-GNAI2 antibody produced in rabbit Prestige Antibodies^™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	human
G4915	Anti-Gα_i1,2 antibody produced in rabbit whole antiserum	mammals
WH0002771M2	Monoclonal Anti-GNAI2 antibody produced in mouse clone 3G11, purified immunoglobulin, buffered aqueous solution	human
G9792	Monoclonal Anti-Gα_i2 antibody produced in mouse ~1 mg/mL, clone R4.5, purified immunoglobulin, buffered aqueous solution	human, rat, mouse, bovine, guinea pig

MISSION shRNA

Type	Description
SHGLY-NM_002070	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_002070	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_002070	MISSION^® shRNA Plasmid DNA

MISSION siRNA Panels

Product #	Description
SI00100	MISSION^® siRNA Human Druggable Genome Library 6650 targets
SI15100	MISSION^® siRNA Human Gene Family Panels Cell Regulation Panel, 227 targets

siRNA

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siRNA ID	RefSeq ID	Approx. siRNA Start	siRNA Type	Ranking
SASI_Hs01_00199944	NM_002070	319	MISSION® siRNA	1
SASI_Hs01_00199945	NM_002070	1108