GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3

Activation of PKA through GPCR; Akt Signaling; Alpha-Adrenergic Signaling; Beta-Adrenergic Signaling; CDK5 Pathway; CREB Pathway; ERK Signaling; GHRH Signaling; GPCR Pathway; IP3 Pathway; Intracellular Calcium Signaling; Melatonin Signaling; P2Y Receptor Signaling; PI3K Signaling; WNT Signaling; cAMP Pathway; p70S6K Signaling; AMPK Enzyme Complex Pathway; Actin Nucleation and Branching; Actin Nucleation by ARP-WASP Complex; Actin-Based Motility by Rho Family GTPases; Activation of cAMP-Dependent PKA; Androgen Signaling; Antiproliferative Role of SSTR2; CRHR Pathway; CXCR4 Pathway; Dopamine-DARPP32 Feedback onto cAMP Pathway; Endothelin-1 Signaling Pathway; EphB-EphrinB Signaling; Estrogen Pathway; GnRH Signaling; Hedgehog Signaling in Mammals; Huntington Disease Pathway; NFAT and Cardiac Hypertrophy; NgRp75(NTR)-Mediated Signaling; S-1P Stimulated Signaling; Signaling Involved in Cardiac Hypertrophy; Thrombin Signaling through PARs; Visual Cycle in Retinal Rods; eNOS Signaling; fMLP Pathway;
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Gene and Product Information
GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3

Properties

Official Symbol

GNAI3

Species

Homo sapiens

Entrez Gene ID

2773

Alternate Symbol

GNAI3; 87U6; FLJ26559

Refseq ID(s)

NM_006496

Accession No.(s)

AF493907; AK130069; BC025285; BT019973; BT019974; more...

Protein ID(s)

NP_006487

Homolog(s)

Gnai3(Mouse); Gnai3(Rat)

Function(s)

GTPase; signal transducer

Pathway(s)

Activation of PKA through GPCR; Akt Signaling; Alpha-Adrenergic Signaling; Beta-Adrenergic Signaling; CDK5 Pathway; more...

Available Product(s)

siRNA, Antibodies, shRNA

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
G4040	Anti-Gα i3 antibody produced in rabbit whole antiserum, aqueous glycerol solution	human, rat, mouse, hamster

MISSION shRNA

Type	Description
SHGLY-NM_006496	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_006496	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_006496	MISSION^® shRNA Plasmid DNA

siRNA

Click to view price

siRNA ID	RefSeq ID	Approx. siRNA Start	siRNA Type	Ranking
SASI_Hs01_00129966	NM_006496	720	MISSION® siRNA	1
SASI_Hs01_00129967	NM_006496	1193	MISSION® siRNA	2
SASI_Hs01_00129968	NM_006496	1084	MISSION® siRNA	3
SASI_Hs01_00129969	NM_006496	346	MISSION® siRNA	4
SASI_Hs01_00129970	NM_006496	910	MISSION® siRNA	5
SASI_Hs01_00129971	NM_006496	265	MISSION® siRNA	6
SASI_Hs01_00129972	NM_006496	939	MISSION® siRNA	7
SASI_Hs01_00129973	NM_006496	220	MISSION® siRNA	8
SASI_Hs01_00129974	NM_006496	539	MISSION® siRNA	9
SASI_Hs01_00129975	NM_006496	212	MISSION® siRNA	10

Sigma's MISSION^® siRNA have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. Critical rules incorporated into the best-in-class Rosetta siRNA design algorithm lead to siRNA of increased target specificity and knockdown for low abundance messages.