GRB2 growth factor receptor-bound protein 2

CREB Pathway; Caspase Cascade; EGF Pathway; ERK Signaling; ErbB Family Pathway; FGF Pathway; FLT3 Signaling; GPCR Pathway; HGF Pathway; IGF1R Signaling; IP3 Pathway; ITK And TCR Signaling; Insulin Receptor Pathway; Integrin Pathway; JNK Pathway; MAPK Family Pathway; MAPK Signaling; Molecular Mechanisms of Cancer; NGF Pathway; PDGF Pathway; PI3K Signaling; PKC-Theta Pathway; PPAR Pathway; PTEN Pathway; Paxillin Interactions; Rap1 Pathway; Ras Pathway; TCR Signaling; TRKA Signaling; VEGF Pathway; eIF2 Pathway; p38 Signaling; p70S6K Signaling; 14-3-3 Induced Intracellular Signaling; Activation of cAMP-Dependent PKA; Angiopoietin-TIE2 Signaling; BAD Phosphorylation; BCR Pathway; BDNF Pathway; CCKBR-Gastrin Stimulated Signaling; CD28 Signaling in T-Helper Cell; CNTF Signaling; CXCR4 Pathway; Calpain Protease Regulates Cellular Mechanics; Chemokine Signaling; Endothelin-1 Signaling Pathway; ErbB2-ErbB3 Heterodimers; ErbB4 Pathway; Erythropoietin Pathway; Estrogen Pathway; FAK1 Signaling; Fc-EpsilonRI Pathway; Fc-Gamma-RIIB Signaling in B-Cells; GDNF-Family Ligands and Receptor Interactions; GnRH Signaling; ICos-ICosL Pathway in T-Helper Cell; IL-2 Pathway; IL-3 Pathway; IL-4 Pathway; IL-6 Pathway; Internalin Pathway; Mucosal Healing through Trefoil Factors; NFAT in Immune Response; OSM Pathway; Prolactin Signaling; Regulation of eIF4 and p70S6K; Renin-Angiotensin Pathway; Signaling Involved in Cardiac Hypertrophy; TGF-Beta Pathway; TREM1 Pathway; Thrombin Signaling through PARs; Thrombopoietin Pathway; UPAUPAR Pathway; Vav Signaling in T-Lymphocyte;
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Gene and Product Information
GRB2	growth factor receptor-bound protein 2

Properties

Official Symbol

GRB2

Species

Homo sapiens

Entrez Gene ID

2885

Alternate Symbol

GRB2; ASH; EGFRBP-GRB2; GRB3-3; MST084; MSTP084

Other Designations

HT027; abundant SRC homology; epidermal growth factor receptor-binding protein GRB2; growth factor receptor-bound protein 3

Refseq ID(s)

NM_002086; NM_203506

Accession No.(s)

AA452034; AF171699; AF246238; AF302079; AF498925; more...

Protein ID(s)

NP_002077; NP_987102

Homolog(s)

Grb2(Mouse); Grb2(Rat)

Function(s)

signal transducer

Pathway(s)

CREB Pathway; Caspase Cascade; EGF Pathway; ERK Signaling; ErbB Family Pathway; more...

Replaces Gene ID(s)

80715; 80299

Available Product(s)

siRNA, Antibody Arrays, Antibodies, Proteins, MISSION shRNA Panels, shRNA

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
WH0002885M1	Monoclonal Anti-GRB2 antibody produced in mouse clone 4C6-H6, ascites fluid, buffered aqueous solution	human
G2791	Monoclonal Anti-Grb-2 antibody produced in mouse ~2 mg/mL, clone GRB-232, purified immunoglobulin, buffered aqueous solution	human, mouse, rat

Proteins

Product #	Description
G5650	Grb2 SH2-domain Protein A fusion protein ≥90% (SDS-PAGE), recombinant, expressed in Escherichia coli, lyophilized powder

MISSION shRNA

Type	Description
SHGLY-NM_002086	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_002086	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_002086	MISSION^® shRNA Plasmid DNA

MISSION shRNA Panels

Product #	Description
SH1911	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock Apoptosis Pathway
SH2711	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock JAK-STAT Pathway
SH1921	MISSION^® shRNA Human Gene Family Set, DNA Apoptosis Pathway
SH2721	MISSION^® shRNA Human Gene Family Set, DNA JAK-STAT Pathway
SH1931	MISSION^® shRNA Human Gene Family Set, Lentiviral Particles Apoptosis Pathway
SH2731	MISSION^® shRNA Human Gene Family Set, Lentiviral Particles JAK-STAT Pathway

Antibody Arrays

Product #	Description
CSAA1	Panorama^® Antibody Microarray - Cell Signaling Kit
MPAA3	Panorama^® Antibody Microarray - MAPK and PKC Pathways Kit