NRG1 neuregulin 1

Activation of PKA through GPCR; Akt Signaling; CREB Pathway; ERK Signaling; ErbB Family Pathway; GSK3 Signaling; Intracellular Calcium Signaling; Molecular Mechanisms of Cancer; PAK Pathway; PI3K Signaling; PPAR Pathway; PTEN Pathway; Paxillin Interactions; Rap1 Pathway; cAMP Pathway; eIF2 Pathway; p70S6K Signaling; 14-3-3 Induced Intracellular Signaling; Actin-Based Motility by Rho Family GTPases; Activation of cAMP-Dependent PKA; Agrin Interaction at Neuromuscular Junction; Apoptotic Pathways in Synovial Fibroblasts; Cellular Apoptosis Pathway; ErbB2-ErbB3 Heterodimers; ErbB4 Pathway; Mitochondrial Apoptosis; Nuclear Receptor Activation by Vitamin-A; Renin-Angiotensin Pathway; Tec Kinases Signaling; Telomerase Components in Cell Signaling; eNOS Signaling;
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Gene and Product Information
NRG1	neuregulin 1

Properties

Official Symbol

NRG1

Species

Homo sapiens

Entrez Gene ID

3084

Alternate Symbol

NRG1; ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; NDF; SMDF

Other Designations

glial growth factor; heregulin, alpha (45kD, ERBB2 p185-activator); neu differentiation factor; sensory and motor neuron derived factor

Refseq ID(s)

NM_004495; NM_013956; NM_013957; NM_013958; NM_013959; NM_013960; NM_013961; NM_013962; NM_013964

Accession No.(s)

AF026146; AK097005; AK223435; AY207002; BC006492; more...

Protein ID(s)

NP_004486; NP_039250; NP_039251; NP_039252; NP_039253; NP_039254; NP_039255; NP_039256; NP_039258

Homolog(s)

Nrg1(Mouse); Nrg1(Rat)

Function(s)

growth factor/ligand/cytokine/chemokine; molecular function unknown; transcription factor

Pathway(s)

Activation of PKA through GPCR; Akt Signaling; CREB Pathway; ERK Signaling; ErbB Family Pathway; more...

Available Product(s)

siRNA, Antibodies, Proteins, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
HPA010964	Anti-NRG1 antibody produced in rabbit Prestige Antibodies^™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	human

Proteins

Product #	Description
H5529	Heregulin-α, EGF Domain human ≥97% (SDS-PAGE), recombinant, expressed in Escherichia coli, lyophilized powder, cell culture tested
H0786	Heregulin-β, EGF Domain human ~80% (SDS-PAGE), recombinant, expressed in Escherichia coli, buffered aqueous glycerol solution
H7660	Heregulin-β1 (EGF Domain) human ≥98% (SDS-PAGE and HPLC), recombinant, expressed in Escherichia coli, lyophilized powder

MISSION shRNA

Type	Description
SHGLY-NM_004495	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_004495	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_004495	MISSION^® shRNA Plasmid DNA

MISSION siRNA Panels

Product #	Description
SI00100	MISSION^® siRNA Human Druggable Genome Library 6650 targets
SI04100	MISSION^® siRNA Human Gene Family Panels Human Growth Factors/Receptors Panel, 375 targets