APP amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)

Gene and Product Information
APP	amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)

Properties

Official Symbol

APP

Species

Homo sapiens

Entrez Gene ID

351

Alternate Symbol

APP; AAA; ABETA; ABPP; AD1; APPI; CTFGAMMA; CVAP; PN2

Other Designations

A4 amyloid protein; amyloid beta A4 protein; amyloid-beta protein; beta-amyloid peptide; cerebral vascular amyloid peptide; protease nexin-II

Refseq ID(s)

NM_000484; NM_201413; NM_201414

Accession No.(s)

A02759; AB066441; AF282245; BC004369; BC065523; more...

Protein ID(s)

NP_000475; NP_958816; NP_958817

Homolog(s)

App(Mouse); App(Rat)

Function(s)

apoptosis; cell adhesion; protease inhibitor; protein binding; vesicle-mediated transport

Pathway(s)

Alzheimers Disease Pathway; Reelin Pathway (Cajal-Retzius cells)

Available Product(s)

siRNA, Small Molecule - Antagonist, Antibody Arrays, Antibodies, Proteins, MISSION shRNA Panels, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
HPA001462	Anti-APP antibody produced in rabbit Prestige Antibodies^™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	human
A1976	Anti-Amyloid Peptide β, Cleavage Site 42 antibody produced in rabbit affinity isolated antibody, buffered aqueous solution	human, mouse, rat
A2101	Anti-Amyloid Peptide β, Cleavage Site 43 antibody produced in rabbit affinity isolated antibody, buffered aqueous solution	human, mouse
A8717	Anti-Amyloid Precursor Protein, C-Terminal antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution	mouse, rat, human
A8842	Anti-Amyloid Precursor Protein, KPI Domain antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution	human, rat, mouse
A8967	Anti-Amyloid Precursor Protein, N-Terminal antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution	human, mouse, rat
A3356	Anti-β-Amyloid (22-35) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution	human, mouse, rat
A8326	Anti-β-Amyloid Protein (1-40) antibody produced in rabbit whole antiserum	human
A9103	Anti-phospho-APP (pThr⁶⁶⁸) antibody produced in rabbit affinity isolated antibody, aqueous glycerol solution, 10 blots	human
A1474	Monoclonal Anti-β-Amyloid (1-17) antibody produced in mouse ~1 mg/mL, clone 6E10, purified immunoglobulin, buffered aqueous solution	human
A1349	Monoclonal Anti-β-Amyloid (17-24) antibody produced in mouse ~1 mg/mL, clone 4G8, purified immunoglobulin, buffered aqueous solution	human
A8978	Monoclonal Anti-β-Amyloid [13-28] antibody produced in mouse ~2 mg/mL, clone BAM90.1, purified immunoglobulin, buffered aqueous solution	human
A5213	Monoclonal Anti-β-Amyloid antibody produced in mouse clone BAM-10, ascites fluid	human
A3981	Monoclonal Anti-β-Amyloid antibody produced in mouse ~1.5 mg/mL, clone BAM-10, purified immunoglobulin, buffered aqueous solution	human
A8354	Monoclonal Anti-β-Amyloid antibody produced in mouse ~2 mg/mL, clone NAB 228, purified immunoglobulin, buffered aqueous solution	human

Proteins

Product #	Description
A1222	7-Methoxycoumarin-4-acetyl-[Asn⁶⁷⁰, Leu⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 Fragment 667-674-(2,4-dinitrophenol)Dap ≥97% (HPLC)