FAS Fas (TNF receptor superfamily, member 6)

Akt Signaling; Apoptosis through Death Receptors; Caspase Cascade; Molecular Mechanisms of Cancer; PI3K Signaling; STAT3 Pathway; p38 Signaling; p53 Signaling; Apoptotic Pathways Triggered By HIV1; Apoptotic Pathways in Synovial Fibroblasts; CCR5 Pathway in Macrophages; CTL Mediated Apoptosis; Cellular Apoptosis Pathway; Fas Signaling; H. pylori Activated Signaling; Mitochondrial Apoptosis; NFAT Signaling and Lymphocyte Interactions; PEDF Induced Signaling; Pathogenesis of Helicobacter pylori Infection; SUMO Pathway; TNF Superfamily Pathway; Tec Kinases Signaling; Tumoricidal Effects of Hepatic NK Cells; c-Myc and Apoptosis;
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Gene and Product Information
FAS	Fas (TNF receptor superfamily, member 6)

Properties

Official Symbol

FAS

Species

Homo sapiens

Entrez Gene ID

355

Alternate Symbol

FAS; ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6

Refseq ID(s)

NM_000043; NM_152871; NM_152872; NM_152873; NM_152874; NM_152875; NM_152876; NM_152877

Other Designations

APO-1 cell surface antigen; CD95 antigen; Fas antigen; OTTHUMP00000059646; apoptosis antigen 1; tumor necrosis factor receptor superfamily, member 6

Accession No.(s)

AB209361; BC012479; CR450307; CR625848; DQ894675; more...

Protein ID(s)

NP_000034; NP_690610; NP_690611; NP_690612; NP_690613; NP_690614; NP_690615; NP_690616

Homolog(s)

Fas(Mouse); Tnfrsf6(Rat)

Function(s)

apoptosis; protein binding; signal transducer

Pathway(s)

Akt Signaling; Apoptosis through Death Receptors; Caspase Cascade; Molecular Mechanisms of Cancer; PI3K Signaling; more...

Available Product(s)

siRNA, Antibody Arrays, Antibodies, Proteins, MISSION shRNA Panels, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
WH0000355M5	Monoclonal Anti-FAS antibody produced in mouse clone 2G3, purified immunoglobulin, buffered aqueous solution	human
F4424	Monoclonal Anti-Fas (CD95/Apo-1) antibody produced in mouse clone DX2, purified immunoglobulin, buffered aqueous solution	human
F4229	Monoclonal Anti-Fas (CD95/Apo-1)−FITC antibody produced in mouse clone DX2, purified immunoglobulin, buffered aqueous solution	human

Proteins

Product #	Description
F2053	Fas Intracellular Domain human >90% (SDS-PAGE), recombinant, expressed in Escherichia coli (N-terminal histidine tagged), buffered aqueous solution
F8674	Fas/Fc Chimera human ≥97% (SDS-PAGE), recombinant, expressed in mouse NSO cells, lyophilized powder, cell culture tested

MISSION shRNA

Type	Description
SHGLY-NM_000043	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_000043	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_000043	MISSION^® shRNA Plasmid DNA

MISSION shRNA Panels

Product #	Description
SH1911	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock Apoptosis Pathway
SH2811	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock T-Cell Activation
SH2411	MISSION^® shRNA Human Gene Family