IL1A interleukin 1, alpha

Akt Signaling; MAPK Family Pathway; MAPK Signaling; PAK Pathway; PI3K Signaling; SOCS Pathway; STAT3 Pathway; p38 Signaling; 14-3-3 Induced Apoptosis; Airway Pathology in COPD; Bacterial Meningitis; Cellular Immune Responses to HBV; Cytokine Network; Glucocorticoid Receptor Signaling; H. pylori Activated Signaling; HMGB1 Pathway; IL-1 Pathway; IL-10 Pathway; IL-6 Pathway; MIF Mediated Glucocorticoid Regulation; MIF Regulation of Innate Immune Cells; NF-KappaB Family Pathway; NFAT Signaling and Lymphocyte Interactions; PEDF Induced Signaling; PGC1Alpha Pathway; Pathogenesis of Rheumatoid Arthritis; Regulation of eIF4 and p70S6K; SUMO Pathway; Shigella Invasion; TGF-Beta Pathway; TRAF Pathway; TREM1 Pathway; Tec Kinases Signaling; Virus-Induced Airway Inflammation; all-trans-Retinoic Acid Signaling in Brain;
collapse

Gene and Product Information
IL1A	interleukin 1, alpha

Properties

Official Symbol

IL1A

Species

Homo sapiens

Entrez Gene ID

3552

Alternate Symbol

IL1A; IL-1A; IL1; IL1-ALPHA; IL1F1

Refseq ID(s)

NM_000575

Other Designations

IL1A (IL1F1); hematopoietin-1; preinterleukin 1 alpha; pro-interleukin-1-alpha

Accession No.(s)

BC013142; BC035169; BT007014; CA307202; CR457414; more...

Protein ID(s)

NP_000566

Homolog(s)

Il1a(Mouse); Il1a(Rat)

Function(s)

apoptosis; signal transducer

Pathway(s)

Akt Signaling; MAPK Family Pathway; MAPK Signaling; PAK Pathway; PI3K Signaling; more...

Available Product(s)

siRNA, Small Molecule - Antagonist, Antibodies, MISSION shRNA Panels, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
I8909	Anti-Interleukin-1α antibody produced in goat IgG fraction of antiserum, lyophilized powder	human
I8284	Anti-Interleukin-1α antibody produced in goat affinity isolated antibody, lyophilized powder	human
I5018	Anti-Interleukin-1α antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution	human
I9034	Anti-Interleukin-1α propeptide antibody produced in sheep affinity isolated antibody, lyophilized powder	human
WH0003552M1	Monoclonal Anti-IL1A antibody produced in mouse clone 4B8, purified immunoglobulin, buffered aqueous solution	human
I7659	Monoclonal Anti-Interleukin-1α antibody produced in mouse clone 3405, purified immunoglobulin, lyophilized powder	human
I7534	Monoclonal Anti-Interleukin-1α antibody produced in mouse clone 4414, purified immunoglobulin, lyophilized powder	human
I7409	Monoclonal Anti-Interleukin-1α propeptide antibody produced in mouse clone 409405, purified immunoglobulin, lyophilized powder	human

Small Molecule - Antagonist

Product #	Description
I7378	Indomethacin ≥99% (TLC)
I8280	Indomethacin meets USP testing specifications

MISSION shRNA

Type	Description
SHGLY-NM_000575	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_000575	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_000575	MISSION^® shRNA Plasmid DNA

MISSION shRNA Panels

Product #	Description
SH0811	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock Cytokines and Chemokines
SH0821	MISSION^® shRNA Human Gene Family Set, DNA Cytokines and Chemokines
SH0831	MISSION^® shRNA Human Gene Family Set, Lentiviral Particles Cytokines and Chemokines

MISSION siRNA Panels

Product #	Description
SI00100	MISSION^® siRNA Human Druggable Genome Library 6650 targets
SI04100	MISSION^® siRNA Human Gene Family Panels Human Growth Factors/Receptors Panel, 375 targets