IL1B interleukin 1, beta

Akt Signaling; MAPK Family Pathway; MAPK Signaling; PAK Pathway; PI3K Signaling; SOCS Pathway; STAT3 Pathway; p38 Signaling; 14-3-3 Induced Apoptosis; Airway Pathology in COPD; Bacterial Meningitis; C. pneumoniae Infection in Atherosclerosis; Cellular Immune Responses to HBV; Cytokine Network; Glucocorticoid Receptor Signaling; H. pylori Activated Signaling; HMGB1 Pathway; IL-1 Pathway; IL-10 Pathway; IL-6 Pathway; LDL Oxidation in Atherogenesis; MIF Mediated Glucocorticoid Regulation; MIF Regulation of Innate Immune Cells; MSP-RON Signaling; Murine MSP-STK Signaling; NF-KappaB Family Pathway; NFAT Signaling and Lymphocyte Interactions; PEDF Induced Signaling; PGC1Alpha Pathway; Pathogenesis of Helicobacter pylori Infection; Regulation of eIF4 and p70S6K; SUMO Pathway; Shigella Invasion; TGF-Beta Pathway; TRAF Pathway; TREM1 Pathway; Tec Kinases Signaling; Virus-Induced Airway Inflammation; all-trans-Retinoic Acid Signaling in Brain;
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Gene and Product Information
IL1B	interleukin 1, beta

Properties

Official Symbol

IL1B

Species

Homo sapiens

Entrez Gene ID

3553

Alternate Symbol

IL1B; IL-1; IL1-BETA; IL1F2

Other Designations

catabolin; preinterleukin 1 beta; pro-interleukin-1-beta

Refseq ID(s)

NM_000576

Accession No.(s)

AF043335; BC008678; BT007213; CR407679; DQ890673; more...

Protein ID(s)

NP_000567

Homolog(s)

Il1b(Mouse); Il1b(Rat)

Function(s)

apoptosis; signal transducer

Pathway(s)

Akt Signaling; MAPK Family Pathway; MAPK Signaling; PAK Pathway; PI3K Signaling; more...

Available Product(s)

siRNA, Small Molecule - Antagonist, Antibodies, Small Molecule - Inhibitor, Proteins, MISSION shRNA Panels, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
HPA001410	Anti-IL1B antibody produced in rabbit Prestige Antibodies^™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	human
I4893	Anti-Interleukin-1β antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution	human
WH0003553M1	Monoclonal Anti-IL1B antibody produced in mouse clone 2A8, purified immunoglobulin, buffered aqueous solution	human
I3642	Monoclonal Anti-Interleukin-1β antibody produced in mouse clone 8516.311, purified immunoglobulin, lyophilized powder	human

Proteins

Product #	Description
I4638	Interleukin-1β Fragment 163-171 human ≥97% (HPLC), synthetic
I9401	Interleukin-1β human recombinant, expressed in Escherichia coli, cell culture tested

Small Molecule - Inhibitor

Product #	Description
100633	1-(2-Hydroxyphenyl)-3-phenyl-2-propenone 98%
56165	1-(2-Hydroxyphenyl)-3-phenyl-2-propenone purum, ≥98.0% (HPLC)
157465	4′-Methoxychalcone 97%
136123	trans-Chalcone 97%

Small Molecule - Antagonist

Product #	Description
P9672	Probucol
S8307	SB 203580 solid
S0193	SKF-86002 ≥98% (HPLC), solid

MISSION shRNA

Type	Description
SHGLY-NM_000576	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_000576	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_000576	MISSION^® shRNA Plasmid DNA

MISSION shRNA Panels

Product #	Description
SH0811