KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Activation of PKA through GPCR; Akt Signaling; CREB Pathway; ERK Signaling; GPCR Pathway; GSK3 Signaling; Intracellular Calcium Signaling; JNK Pathway; Molecular Mechanisms of Cancer; P2Y Receptor Signaling; PAK Pathway; PI3K Signaling; PPAR Pathway; PTEN Pathway; Paxillin Interactions; Ras Pathway; cAMP Pathway; eIF2 Pathway; p38 Signaling; p70S6K Signaling; 14-3-3 Induced Intracellular Signaling; Actin Nucleation and Branching; Actin Nucleation by ARP-WASP Complex; Actin-Based Motility by Rho Family GTPases; Activation of cAMP-Dependent PKA; Apoptotic Pathways in Synovial Fibroblasts; Cellular Apoptosis Pathway; Endothelin-1 Signaling Pathway; Estrogen Pathway; Melanocyte Development and Pigmentation; Mitochondrial Apoptosis; NFAT in Immune Response; Nuclear Receptor Activation by Vitamin-A; Renin-Angiotensin Pathway; Telomerase Components in Cell Signaling; Yersinia Infection; eNOS Signaling;
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Gene and Product Information
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Properties

Official Symbol

KIT

Species

Homo sapiens

Entrez Gene ID

3815

Alternate Symbol

KIT; C-KIT; CD117; SCFR

Refseq ID(s)

NM_000222

Other Designations

mast/stem cell growth factor receptor; proto-oncogene tyrosine-protein kinase Kit

Accession No.(s)

AC006552; AC092545; AJ438313; BC071593; CN414753; more...

Protein ID(s)

NP_000213

Homolog(s)

Kit(Mouse); Kit(Rat)

Function(s)

growth factor/ligand/cytokine/chemokine receptor; signal transducer; transferase

Pathway(s)

Activation of PKA through GPCR; Akt Signaling; CREB Pathway; ERK Signaling; GPCR Pathway; more...

Replaces Gene ID(s)

5086

Available Product(s)

siRNA, Antibodies, Small Molecule - Inhibitor, Proteins, MISSION shRNA Panels, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
HPA004471	Anti-KIT antibody produced in rabbit Prestige Antibodies^™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	human
S2562	Anti-Stem Cell Factor Receptor (SCF R) antibody produced in goat affinity isolated antibody, lyophilized powder	human
C6740	Anti-phospho-c-Kit (SCFR) (pTyr⁷⁰³) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution	human, mouse, rat
C6615	Anti-phospho-c-Kit (SCFR) (pTyr⁷³⁰) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution	human, mouse, rat
C6490	Anti-phospho-c-Kit (SCFR) (pTyr⁸²³) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution	human, canine, mouse, rat
C6365	Anti-phospho-c-Kit (SCFR) (pTyr⁹³⁶) antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution	human, canine, mouse, rat
WH0003815M2	Monoclonal Anti-KIT antibody produced in mouse clone 6F2, purified immunoglobulin, buffered aqueous solution	human

Proteins

Product #	Description
S2437	SCF Soluble Receptor human >95% (SDS-PAGE), recombinant, expressed in Sf21 cells, lyophilized powder

Small Molecule - Inhibitor

Product #	Description
E3380	Ellipticine synthetic

MISSION shRNA

Type	Description
SHGLY-NM_000222	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_000222	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_000222	MISSION^® shRNA Plasmid DNA

MISSION shRNA Panels

Product #	Description
SHX001	MISSION^® LentiExpress^™ Human Kinases
SH0111	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock Kinases
SH0121	MISSION^® shRNA Human Gene Family Set, DNA Kinases
SH0131	MISSION^® shRNA Human Gene Family Set, Lentiviral Particles Kinases

MISSION siRNA Panels

Product #