NTRK2 neurotrophic tyrosine kinase, receptor, type 2

Activation of PKA through GPCR; Akt Signaling; CDK5 Pathway; CREB Pathway; ERK Signaling; GPCR Pathway; GSK3 Signaling; Intracellular Calcium Signaling; JNK Pathway; Molecular Mechanisms of Cancer; P2Y Receptor Signaling; PAK Pathway; PI3K Signaling; PPAR Pathway; PTEN Pathway; Paxillin Interactions; Rap1 Pathway; Ras Pathway; cAMP Pathway; eIF2 Pathway; p38 Signaling; p70S6K Signaling; 14-3-3 Induced Intracellular Signaling; Actin Nucleation and Branching; Actin Nucleation by ARP-WASP Complex; Actin-Based Motility by Rho Family GTPases; Activation of cAMP-Dependent PKA; Alzheimers Disease Pathway; Apoptotic Pathways in Synovial Fibroblasts; BDNF Pathway; Cellular Apoptosis Pathway; Endothelin-1 Signaling Pathway; Estrogen Pathway; Guidance Cues and Growth Cone Motility; Mitochondrial Apoptosis; NFAT in Immune Response; Neuropathic Pain - Signaling in Dorsal Horn Neurons; Nuclear Receptor Activation by Vitamin-A; Renin-Angiotensin Pathway; Signaling Involved in Cardiac Hypertrophy; Tec Kinases Signaling; Telomerase Components in Cell Signaling; Yersinia Infection; eNOS Signaling;
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Gene and Product Information
NTRK2	neurotrophic tyrosine kinase, receptor, type 2

Properties

Official Symbol

NTRK2

Species

Homo sapiens

Entrez Gene ID

4915

Alternate Symbol

NTRK2; GP145-TRKB; TRKB

Refseq ID(s)

NM_001007097; NM_001018064; NM_001018065; NM_001018066; NM_006180

Other Designations

BDNF/NT-3 growth factors receptor; tyrosine kinase receptor B

Accession No.(s)

AB209118; AF086101; AF400441; AF410898; AF410899; more...

Protein ID(s)

NP_001007098; NP_001018074; NP_001018075; NP_001018076; NP_006171

Homolog(s)

Ntrk2(Mouse); Ntrk2(Rat)

Function(s)

protein kinase; signal transducer; transferase

Pathway(s)

Activation of PKA through GPCR; Akt Signaling; CDK5 Pathway; CREB Pathway; ERK Signaling; more...

Available Product(s)

siRNA, Antibodies, Proteins, MISSION shRNA Panels, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
HPA007637	Anti-NTRK2 antibody produced in rabbit Prestige Antibodies^™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	human
T1941	Anti-TrkB antibody produced in goat affinity isolated antibody, lyophilized powder	human
WH0004915M1	Monoclonal Anti-NTRK2 antibody produced in mouse clone 4D3-F10, purified immunoglobulin, buffered aqueous solution	human

Proteins

Product #	Description
T8694	TrkB/Fc Chimera human >90% (SDS-PAGE), recombinant, expressed in mouse NSO cells, lyophilized powder

MISSION shRNA

Type	Description
SHGLY-NM_006180	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_006180	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_006180	MISSION^® shRNA Plasmid DNA

MISSION shRNA Panels

Product #	Description
SHX001	MISSION^® LentiExpress^™ Human Kinases
SH0111	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock Kinases
SH0121	MISSION^® shRNA Human Gene Family Set, DNA Kinases
SH0131	MISSION^® shRNA Human Gene Family Set, Lentiviral Particles Kinases

MISSION siRNA Panels

Product #	Description
SI00100	MISSION^® siRNA Human Druggable Genome Library 6650 targets
SI14100	MISSION^® siRNA Human Gene Family Panels Cell Surface and Nuclear Receptors Panel, 722 targets
SI02100	MISSION^® siRNA Human Gene Family Panels Kinase Panel, 714 targets

siRNA

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