PAK1 p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)

CDK5 Pathway; Caspase Cascade; EGF Pathway; ERK Signaling; ErbB Family Pathway; GPCR Pathway; HGF Pathway; Integrin Pathway; JNK Pathway; LPS Stimulated MAPK Signaling; MAPK Family Pathway; MAPK Signaling; PAK Pathway; PDGF Pathway; PI3K Signaling; Paxillin Interactions; Ras Pathway; TCR Signaling; p38 Signaling; Actin Nucleation and Branching; Actin-Based Motility by Rho Family GTPases; Agrin Interaction at Neuromuscular Junction; Angiopoietin-TIE2 Signaling; BCR Pathway; CCR3 Pathway in Eosinophils; CD28 Signaling in T-Helper Cell; CXCR4 Pathway; EphB-EphrinB Signaling; EphrinA-EphR Signaling; FAK1 Signaling; Fas Signaling; GDNF-Family Ligands and Receptor Interactions; GnRH Signaling; Guidance Cues and Growth Cone Motility; H. pylori Activated Signaling; Internalin Pathway; NgRp75(NTR)-Mediated Signaling; Renin-Angiotensin Pathway; RhoGDI Pathway; Semaphorin Signaling; TNFR1 Pathway; Tec Kinases Signaling; Vav Signaling in T-Lymphocyte;
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Gene and Product Information
PAK1	p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)

Properties

Official Symbol

PAK1

Species

Homo sapiens

Entrez Gene ID

5058

Alternate Symbol

PAK1; MGC130000; MGC130001; PAKALPHA

Other Designations

p21-activated kinase 1; p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)

Refseq ID(s)

NM_002576

Accession No.(s)

AF071884; AK055228; BC050377; BC109298; BC109299; more...

Protein ID(s)

NP_002567

Homolog(s)

Pak1(Mouse); Pak1(Rat)

Function(s)

apoptosis; protein binding; protein kinase; transferase

Pathway(s)

CDK5 Pathway; Caspase Cascade; EGF Pathway; ERK Signaling; ErbB Family Pathway; more...

Available Product(s)

siRNA, Antibody Arrays, Antibodies, MISSION shRNA Panels, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
HPA003565	Anti-PAK1 antibody produced in rabbit Prestige Antibodies^™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	human
P7871	Anti-phospho-PAK1/2/3 (pSer¹⁴¹) antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution	human
P7746	Anti-phospho-PAK1/2/3 (pThr⁴²³) antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution	human
WH0005058M1	Monoclonal Anti-PAK1 antibody produced in mouse clone 1E11, purified immunoglobulin, buffered aqueous solution	human
P3237	Monoclonal Anti-phospho-PAK1 (pThr²¹²) antibody produced in mouse ~2 mg/mL, clone PK-18, purified immunoglobulin, buffered aqueous solution	human, rat, mouse

MISSION shRNA

Type	Description
SHGLY-NM_002576	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_002576	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_002576	MISSION^® shRNA Plasmid DNA

MISSION shRNA Panels

Product #	Description
SHX001	MISSION^® LentiExpress^™ Human Kinases
SH1911	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock Apoptosis Pathway
SH0111	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock Kinases
SH1921	MISSION^® shRNA Human Gene Family Set, DNA Apoptosis Pathway
SH0121	MISSION^® shRNA Human Gene Family Set, DNA Kinases
SH1931	MISSION^® shRNA Human Gene Family Set, Lentiviral Particles Apoptosis Pathway
SH0131	MISSION^® shRNA Human Gene Family Set, Lentiviral Particles Kinases

MISSION siRNA Panels

Product #	Description
SI00100	MISSION^® siRNA Human Druggable Genome Library 6650 targets
SI02100	MISSION^® siRNA Human Gene Family Panels Kinase Panel, 714 targets

Antibody Arrays

Product #	Description
CSAA1	Panorama^® Antibod