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Gene and Product Information 
PPP2CA  protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform 
Properties
Official Symbol 
PPP2CA
 
Species 
Homo sapiens
 
Entrez Gene ID 
5515
 
Alternate Symbol 
PPP2CA; PP2AC; PP2CA; RP-C
 
Other Designations 
PP2A-alpha; protein phosphatase 2, catalytic subunit, alpha isoform; replication protein C; serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform
 
Refseq ID(s) 
NM_002715
 
Accession No.(s) 
AK057424; AK097599; AV705728; BC000400; BC002657; BC019275; BC031696; BM786995; CR457417; CR594899; CR596427; CR601999; CR619537; CR624778; J03804; NM_002715; X12646
 
Protein ID(s) 
NP_002706
 
Homolog(s) 
Ppp2ca(Mouse); Ppp2ca(Rat)
 
Function(s) 
apoptosis; hydrolase; protein phosphatase; transcription factor; translation factor
 
Pathway(s) 
Akt Signaling; Beta-Adrenergic Signaling; CDK5 Pathway; Ceramide Pathway; Cyclins and Cell Cycle Regulation; ERK Signaling; GSK3 Signaling; MAPK Signaling; PKR Pathway; mTOR Pathway; p70S6K Signaling; AMPK Enzyme Complex Pathway; BAD Phosphorylation; CTLA4 Signaling; Cell Cycle Control by BTG Proteins; ChREBP Regulation in Rattus norvegicus; Dopamine-DARPP32 Feedback onto cAMP Pathway; Erythropoietin Pathway; IL-6 Pathway; Mitotic Roles of Polo-Like Kinase; Reelin Pathway (Cajal-Retzius cells); Regulation of eIF4 and p70S6K; Renin-Angiotensin Pathway; TGF-Beta Pathway
 
Available Product(s) 
siRNA, Antibody Arrays, Antibodies, Small Molecule - Inhibitor, MISSION shRNA Panels, shRNA, MISSION siRNA Panels
 
Useful External Links 
NCBI Gene Info.
 
 
Compendia Bioscience
 
 
Human Protein Reference Database
 
 
PubMed
 
 
Cytoscape
 
 
Gene Expression Tools
Related Products
Product #
Description
Species Reactivity
P8109 Anti-Serine/Threonine Protein Phosphatase 2 A/A antibody produced in rabbit ~1 mg/mL, IgG fraction of antiserum, buffered aqueous solution mouse, rat, bovine, human
P8484 Anti-Serine/Threonine Protein Phosphatase 2 A/C antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution human, mouse, rat, bovine
P8998 Monoclonal Anti-Protein Phosphatase 2Aα (PP2Aα) antibody produced in rat clone 5H4, tissue culture supernatant, buffered aqueous solution human, Xenopus, mouse
P6498 Monoclonal Anti-Protein Phosphatase 2Aα (PP2Aα) antibody produced in rat ~1.5 mg/mL, clone 6F9, purified immunoglobulin, buffered aqueous solution human, frog, mouse, rat

Product #
Description
D6908 DL-erythro-Dihydrosphingosine ≥99%, synthetic
C7632 Cantharidin solid
E7649 Endothall

Type
Description
SHGLY-NM_002715 MISSION® shRNA Bacterial Glycerol Stock
SHVRS-NM_002715 MISSION® shRNA Lentiviral Transduction Particles
SHDNA-NM_002715 MISSION® shRNA Plasmid DNA

Product #
Description
SH2711 MISSION® shRNA Human Gene Family Set, Bacterial Glycerol Stock JAK-STAT Pathway
SH0411 MISSION® shRNA Human Gene Family Set, Bacterial Glycerol Stock Phosphatases
SH2411 MISSION® shRNA Human Gene Family Set, Bacterial Glycerol Stock p53 Pathway
SH2721 MISSION® shRNA Human Gene Family Set, DNA JAK-STAT Pathway
SH0421