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Gene and Product Information 
PPP2R1A  protein phosphatase 2 (formerly 2A), regulatory subunit A , alpha isoform 
Properties
Official Symbol 
PPP2R1A
 
Species 
Homo sapiens
 
Entrez Gene ID 
5518
 
Alternate Symbol 
PPP2R1A; MGC786; PR65A
 
Other Designations 
PP2A, subunit A, PR65-alpha isoform; PP2A, subunit A, R1-alpha isoform; Serine/threonine protein phosphatase 2A, 65 KDA regulatory subunit A, alpha isoform; alpha isoform of regulatory subunit A, protein phosphatase 2; medium tumor antigen-associated 61 KDA protein; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
 
Refseq ID(s) 
NM_014225
 
Accession No.(s) 
AK090488; AK091387; AK130000; AU128747; BC001537; BC026733; BT008074; CR450340; CR604449; CR623106; DQ892756; DQ896000; J02902; NM_014225
 
Protein ID(s) 
NP_055040
 
Homolog(s) 
Ppp2r1a(Mouse); Ppp2r1a(Rat)
 
Function(s) 
apoptosis; protein binding; protein phosphatase; transcription factor; translation factor
 
Pathway(s) 
Akt Signaling; Beta-Adrenergic Signaling; CDK5 Pathway; Ceramide Pathway; Cyclins and Cell Cycle Regulation; ERK Signaling; GSK3 Signaling; MAPK Signaling; PKR Pathway; mTOR Pathway; p70S6K Signaling; BAD Phosphorylation; CTLA4 Signaling; Cell Cycle Control by BTG Proteins; ChREBP Regulation in Rattus norvegicus; Dopamine-DARPP32 Feedback onto cAMP Pathway; Erythropoietin Pathway; IL-6 Pathway; Mitotic Roles of Polo-Like Kinase; Reelin Pathway (Cajal-Retzius cells); Regulation of eIF4 and p70S6K; Renin-Angiotensin Pathway; TGF-Beta Pathway; Telomerase Components in Cell Signaling
 
Available Product(s) 
siRNA, Small Molecule - Inhibitor, MISSION shRNA Panels, shRNA, MISSION siRNA Panels
 
Useful External Links 
NCBI Gene Info.
 
 
Compendia Bioscience
 
 
Human Protein Reference Database
 
 
PubMed
 
 
Cytoscape
 
 
Gene Expression Tools
Related Products
Product #
Description
D6908 DL-erythro-Dihydrosphingosine ≥99%, synthetic
C7632 Cantharidin solid
E7649 Endothall

Type
Description
SHGLY-NM_014225 MISSION® shRNA Bacterial Glycerol Stock
SHVRS-NM_014225 MISSION® shRNA Lentiviral Transduction Particles
SHDNA-NM_014225 MISSION® shRNA Plasmid DNA

Product #
Description
SH0411 MISSION® shRNA Human Gene Family Set, Bacterial Glycerol Stock Phosphatases

Product #
Description
SI00100 MISSION® siRNA Human Druggable Genome Library 6650 targets
SI03100 MISSION® siRNA Human Gene Family Panels Phosphatase Panel, 293 targets

 
 siRNA

siRNA ID
RefSeq ID
Approx. siRNA Start
siRNA Type
Ranking
SASI_Hs01_00232387 NM_014225 938 MISSION® siRNA 1
SASI_Hs01_00232388 NM_014225 1064 MISSION® siRNA 2
SASI_Hs01_00232389 NM_014225 1081 Validated MISSION® siRNA 3
SASI_Hs01_00232390 NM_014225 1737 MISSION® siRNA 4
SASI_Hs01_00232391 NM_014225 1282 MISSION® siRNA 5