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Gene and Product Information 
PPP2R2B  protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform 
Properties
Official Symbol 
PPP2R2B
 
Species 
Homo sapiens
 
Entrez Gene ID 
5521
 
Alternate Symbol 
PPP2R2B; MGC24888; PP2A-PR55B; PR2AB-BETA; PR2AB55-BETA; PR2APR55-BETA; PR52B; PR55-BETA; SCA12
 
Other Designations 
PP2A, subunit B, B-beta isoform; PP2A, subunit B, B55-beta isoform; PP2A, subunit B, PR55-beta isoform; PP2A, subunit B, R2-beta isoform; PP2A-B55beta; Serine/threonine protein phosphatase 2A, 55 kDa regulatory subunit B, beta isoform; Serine/threonine protein phosphatase 2A, neuronal isoform; beta isoform of regulatory subunit B55, protein phosphatase 2; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform; protein phosphatase 2 regulatory subunit B; spinocerebellar ataxia 12
 
Refseq ID(s) 
NM_004576; NM_181674; NM_181675; NM_181676; NM_181677; NM_181678
 
Accession No.(s) 
AK056192; AL540315; AV726282; BC031790; BI669304; BX647887; CR607404; DQ891785; DQ894969; M64930; NM_004576; NM_181674; NM_181675; NM_181676; NM_181677; NM_181678
 
Protein ID(s) 
NP_004567; NP_858060; NP_858061; NP_858062; NP_858063; NP_858064
 
Homolog(s) 
Ppp2r2b(Mouse); Ppp2r2b(Rat)
 
Function(s) 
protein phosphatase
 
Pathway(s) 
Akt Signaling; Beta-Adrenergic Signaling; CDK5 Pathway; Ceramide Pathway; Cyclins and Cell Cycle Regulation; ERK Signaling; GSK3 Signaling; MAPK Signaling; PKR Pathway; mTOR Pathway; p70S6K Signaling; BAD Phosphorylation; CTLA4 Signaling; Cell Cycle Control by BTG Proteins; Dopamine-DARPP32 Feedback onto cAMP Pathway; Erythropoietin Pathway; IL-6 Pathway; Mitotic Roles of Polo-Like Kinase; Reelin Pathway (Cajal-Retzius cells); Regulation of eIF4 and p70S6K; Renin-Angiotensin Pathway; TGF-Beta Pathway; Telomerase Components in Cell Signaling
 
Replaces Gene ID(s) 
56686; 29759
 
Available Product(s) 
siRNA, Small Molecule - Inhibitor, MISSION shRNA Panels, shRNA, MISSION siRNA Panels
 
Useful External Links 
NCBI Gene Info.
 
 
Compendia Bioscience
 
 
Human Protein Reference Database
 
 
PubMed
 
 
Cytoscape
 
 
Gene Expression Tools
Related Products
Product #
Description
D6908 DL-erythro-Dihydrosphingosine ≥99%, synthetic
C7632 Cantharidin solid
E7649 Endothall

Type
Description
SHGLY-NM_004576 MISSION® shRNA Bacterial Glycerol Stock
SHVRS-NM_004576 MISSION® shRNA Lentiviral Transduction Particles
SHDNA-NM_004576 MISSION® shRNA Plasmid DNA

Product #
Description
SH0411 MISSION® shRNA Human Gene Family Set, Bacterial Glycerol Stock Phosphatases

Product #
Description
SI00100 MISSION® siRNA Human Druggable Genome Library 6650 targets
SI03100 MISSION® siRNA Human Gene Family Panels Phosphatase Panel, 293 targets

 
 siRNA

siRNA ID
RefSeq ID
Approx. siRNA Start
siRNA Type
Ranking
SASI_Hs01_00032759 NM_004576 1896 MISSION® siRNA 1
SASI_Hs01_00032760 NM_004576 1814 MISSION® siRNA 2
SASI_Hs01_00032761 NM_004576 1108 MISSION® siRNA 3