BDNF brain-derived neurotrophic factor

Activation of PKA through GPCR; Akt Signaling; CDK5 Pathway; CREB Pathway; ERK Signaling; GSK3 Signaling; Intracellular Calcium Signaling; Molecular Mechanisms of Cancer; PAK Pathway; PI3K Signaling; PPAR Pathway; PTEN Pathway; Paxillin Interactions; Rap1 Pathway; cAMP Pathway; eIF2 Pathway; p70S6K Signaling; 14-3-3 Induced Intracellular Signaling; Actin-Based Motility by Rho Family GTPases; Activation of cAMP-Dependent PKA; Apoptotic Pathways in Synovial Fibroblasts; BDNF Pathway; CRHR Pathway; Cellular Apoptosis Pathway; Guidance Cues and Growth Cone Motility; Mitochondrial Apoptosis; Neuropathic Pain - Signaling in Dorsal Horn Neurons; Nuclear Receptor Activation by Vitamin-A; PEDF Induced Signaling; Renin-Angiotensin Pathway; Tec Kinases Signaling; Telomerase Components in Cell Signaling; eNOS Signaling;
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Gene and Product Information
BDNF	brain-derived neurotrophic factor

Properties

Official Symbol

BDNF

Species

Homo sapiens

Entrez Gene ID

627

Alternate Symbol

BDNF; MGC34632

Other Designations

neurotrophin

Refseq ID(s)

NM_001709; NM_170731; NM_170732; NM_170733; NM_170734; NM_170735

Accession No.(s)

AB038670; AB038671; AB038672; AB038673; AB038674; more...

Protein ID(s)

NP_001700; NP_733927; NP_733928; NP_733929; NP_733930; NP_733931

Homolog(s)

Bdnf(Mouse); Bdnf(Rat)

Function(s)

growth factor/ligand/cytokine/chemokine

Pathway(s)

Activation of PKA through GPCR; Akt Signaling; CDK5 Pathway; CREB Pathway; ERK Signaling; more...

Replaces Gene ID(s)

4949

Available Product(s)

siRNA, Antibodies, Proteins, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
B9186	Anti-Brain-derived Neurotrophic Factor antibody produced in chicken affinity isolated antibody, lyophilized powder	human
P1374	Anti-Pro-BDNF antibody produced in rabbit affinity isolated antibody, lyophilized powder	human, mouse, rat
B9561	Monoclonal Anti-Brain-derived Neurotrophic Factor antibody produced in mouse clone 35909, purified immunoglobulin, lyophilized powder	human
B5050	Monoclonal Anti-Brain-derived Neurotrophic Factor antibody produced in mouse clone 35928.11, purified immunoglobulin, lyophilized powder	human
B9686	Monoclonal Anti-Brain-derived Neurotrophic Factor antibody produced in mouse clone 37129, purified immunoglobulin, lyophilized powder	human
B9436	Monoclonal Anti-Brain-derived Neurotrophic Factor antibody produced in mouse clone 37141, purified immunoglobulin, lyophilized powder	human

Proteins

Product #	Description
B3795	Brain-derived neurotrophic factor human recombinant, expressed in Escherichia coli, cell culture tested

MISSION shRNA

Type	Description
SHGLY-NM_001709	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_001709	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_001709	MISSION^® shRNA Plasmid DNA

MISSION siRNA Panels

Product #	Description
SI00100	MISSION^® siRNA Human Druggable Genome Library 6650 targets
SI04100	MISSION^® siRNA Human Gene Family Panels Human Growth Factors/Receptors Panel, 375 targets

siRNA

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siRNA ID	RefSeq ID	Approx. siRNA Start	siRNA Type	Ranking
SASI_Hs01_00111694	NM_001709	808	MISSION® siRNA	1