CCL3 chemokine (C-C motif) ligand 3

Akt Signaling; JNK Pathway; MAPK Family Pathway; PAK Pathway; PI3K Signaling; Pathogenesis of Multiple Sclerosis; SOCS Pathway; STAT3 Pathway; p38 Signaling; Airway Pathology in COPD; Bacterial Meningitis; C. pneumoniae Infection in Atherosclerosis; CCR5 Pathway in Macrophages; Cellular Immune Responses to HBV; Chemokine Signaling; Glucocorticoid Receptor Signaling; IL-6 Pathway; LDL Oxidation in Atherogenesis; MIF Mediated Glucocorticoid Regulation; MIF Regulation of Innate Immune Cells; NFAT Signaling and Lymphocyte Interactions; PEDF Induced Signaling; PGC1Alpha Pathway; Regulation of eIF4 and p70S6K; TGF-Beta Pathway; Tec Kinases Signaling; all-trans-Retinoic Acid Signaling in Brain;
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Gene and Product Information
CCL3	chemokine (C-C motif) ligand 3

Properties

Official Symbol

CCL3

Species

Homo sapiens

Entrez Gene ID

6348

Alternate Symbol

CCL3; G0S19-1; LD78ALPHA; MIP-1-ALPHA; MIP1A; SCYA3

Refseq ID(s)

NM_002983

Other Designations

LD78 alpha beta; Small inducible cytokine A3; small inducible cytokine A3 (homologous to mouse Mip-1a)

Accession No.(s)

AF043339; BC071834; BX103455; D00044; D63785; more...

Protein ID(s)

NP_002974

Function(s)

cytoskeleton; growth factor/ligand/cytokine/chemokine; signal transducer; vesicle-mediated transport

Pathway(s)

Akt Signaling; JNK Pathway; MAPK Family Pathway; PAK Pathway; PI3K Signaling; more...

Available Product(s)

siRNA, Antibodies, MISSION shRNA Panels, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
M6042	Anti-Macrophage Inflammatory Protein-1α antibody produced in goat IgG fraction of antiserum, lyophilized powder	human
M256	Anti-Macrophage Inflammatory Protein-1α antibody produced in goat affinity isolated antibody, lyophilized powder	human
WH0006348M1	Monoclonal Anti-CCL3 antibody produced in mouse clone 4E7, purified immunoglobulin, buffered aqueous solution	human

MISSION shRNA

Type	Description
SHGLY-NM_002983	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_002983	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_002983	MISSION^® shRNA Plasmid DNA

MISSION shRNA Panels

Product #	Description
SH2811	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock T-Cell Activation
SH2821	MISSION^® shRNA Human Gene Family Set, DNA T-Cell Activation
SH2831	MISSION^® shRNA Human Gene Family Set, Lentiviral Particles T-Cell Activation

MISSION siRNA Panels

Product #	Description
SI00100	MISSION^® siRNA Human Druggable Genome Library 6650 targets
SI04100	MISSION^® siRNA Human Gene Family Panels Human Growth Factors/Receptors Panel, 375 targets

siRNA

Click to view price

siRNA ID	RefSeq ID	Approx. siRNA Start	siRNA Type	Ranking
SASI_Hs01_00079749	NM_002983	281	MISSION® siRNA	1
SASI_Hs01_00079750	NM_002983	272	MISSION® siRNA	2
SASI_Hs01_00079751	NM_002983	618	MISSION® siRNA	3
SASI_Hs01_00079752	NM_002983	144	MISSION® siRNA	4
SASI_Hs01_00079753	NM_002983	135	MISSION® siRNA	5

Sigma's MISSION^® siRNA have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. Critical rules incorporated into the best-in-class Rosetta siRNA design algorithm lead to siRNA of increased target specificity and knockdown for low abundance messages.

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