CCL21 chemokine (C-C motif) ligand 21

Akt Signaling; JNK Pathway; MAPK Family Pathway; PAK Pathway; PI3K Signaling; SOCS Pathway; STAT3 Pathway; p38 Signaling; Airway Pathology in COPD; Bacterial Meningitis; Cellular Immune Responses to HBV; Chemokine Signaling; Glucocorticoid Receptor Signaling; IL-6 Pathway; LT-BetaR Pathway; MIF Mediated Glucocorticoid Regulation; MIF Regulation of Innate Immune Cells; NFAT Signaling and Lymphocyte Interactions; PEDF Induced Signaling; PGC1Alpha Pathway; Regulation of eIF4 and p70S6K; TGF-Beta Pathway; Tec Kinases Signaling; all-trans-Retinoic Acid Signaling in Brain;
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Gene and Product Information
CCL21	chemokine (C-C motif) ligand 21

Properties

Official Symbol

CCL21

Species

Homo sapiens

Entrez Gene ID

6366

Alternate Symbol

CCL21; 6CKINE; CKB9; ECL; MGC34555; SCYA21; SLC; TCA4

Other Designations

Efficient Chemoattractant for Lymphocytes; OTTHUMP00000000526; OTTHUMP00000000527; beta chemokine exodus-2; exodus-2; secondary lymphoid tissue chemokine; small inducible cytokine A21; small inducible cytokine subfamily A (Cys-Cys), member 21

Refseq ID(s)

NM_002989

Accession No.(s)

AB002409; AF001979; AY358887; BC027918; BI833188; more...

Protein ID(s)

NP_002980

Homolog(s)

Ccl21b(Mouse); Ccl21c(Mouse); Ccl21a(Mouse); Ccl21b(Rat)

Function(s)

growth factor/ligand/cytokine/chemokine

Pathway(s)

Akt Signaling; JNK Pathway; MAPK Family Pathway; PAK Pathway; PI3K Signaling; more...

Available Product(s)

siRNA, Antibodies, Proteins, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
C6104	Anti-6Ckine antibody produced in goat affinity isolated antibody, lyophilized powder	human

Proteins

Product #	Description
C0720	6Ckine human ≥97% (SDS-PAGE), recombinant, expressed in Escherichia coli, lyophilized powder

MISSION shRNA

Type	Description
SHGLY-NM_002989	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_002989	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_002989	MISSION^® shRNA Plasmid DNA

MISSION siRNA Panels

Product #	Description
SI00100	MISSION^® siRNA Human Druggable Genome Library 6650 targets
SI04100	MISSION^® siRNA Human Gene Family Panels Human Growth Factors/Receptors Panel, 375 targets

siRNA

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siRNA ID	RefSeq ID	Approx. siRNA Start	siRNA Type	Ranking
SASI_Hs01_00127115	NM_002989	538	MISSION® siRNA	1
SASI_Hs01_00127116	NM_002989	543	MISSION® siRNA	2
SASI_Hs01_00127117	NM_002989	415	MISSION® siRNA	3
SASI_Hs01_00127118	NM_002989	204	MISSION® siRNA	4
SASI_Hs01_00127119	NM_002989	407	MISSION® siRNA	5
SASI_Hs01_00127120	NM_002989	543	MISSION® siRNA	6
SASI_Hs01_00127121	NM_002989	215	MISSION® siRNA	7
SASI_Hs01_00127122	NM_002989	422	MISSION® siRNA	8
SASI_Hs01_00127123	NM_002989	232	MISSION® siRNA	9
SASI_Hs01_00127124	NM_002989	433	MISSION® siRNA	10

Sigma's MISSION^® siRNA have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. Critical rules incorporated into the best-in-class Rosetta siRNA design algorithm lead to siRNA of increased target specificity and knockdown for low abundance messages.