CXCL12 chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)

Activation of PKA through GPCR; Akt Signaling; CREB Pathway; ERK Signaling; Ephrin-Eph Signaling; GSK3 Signaling; Intracellular Calcium Signaling; Molecular Mechanisms of Cancer; PAK Pathway; PI3K Signaling; PPAR Pathway; PTEN Pathway; Paxillin Interactions; Rap1 Pathway; STAT3 Pathway; cAMP Pathway; eIF2 Pathway; p70S6K Signaling; 14-3-3 Induced Intracellular Signaling; Actin-Based Motility by Rho Family GTPases; Activation of cAMP-Dependent PKA; Airway Pathology in COPD; Apoptotic Pathways in Synovial Fibroblasts; Bacterial Meningitis; CXCR4 Pathway; Cellular Apoptosis Pathway; Cellular Immune Responses to HBV; Chemokine Signaling; EphB-EphrinB Signaling; LT-BetaR Pathway; Mitochondrial Apoptosis; NFAT Signaling and Lymphocyte Interactions; Nuclear Receptor Activation by Vitamin-A; PEDF Induced Signaling; Renin-Angiotensin Pathway; Signaling by Slit; Tec Kinases Signaling; Telomerase Components in Cell Signaling; all-trans-Retinoic Acid Signaling in Brain; eNOS Signaling;
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Gene and Product Information
CXCL12	chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)

Properties

Official Symbol

CXCL12

Species

Homo sapiens

Entrez Gene ID

6387

Alternate Symbol

CXCL12; PBSF; SCYB12; SDF-1A; SDF-1B; SDF1; SDF1A; SDF1B; TLSF-A; TLSF-B; TPAR1

Other Designations

stromal cell-derived factor 1; stromal cell-derived factor 1 delta; stromal cell-derived factor 1 gamma; stromal cell-derived factor 1a

Refseq ID(s)

NM_000609; NM_001033886; NM_199168

Accession No.(s)

AI092156; AK090482; AK124641; AL713778; AW014388; more...

Protein ID(s)

NP_000600; NP_001029058; NP_954637

Homolog(s)

Cxcl12(Mouse); Cxcl12(Rat)

Function(s)

cell adhesion; growth factor/ligand/cytokine/chemokine; signal transducer

Pathway(s)

Activation of PKA through GPCR; Akt Signaling; CREB Pathway; ERK Signaling; Ephrin-Eph Signaling; more...

Available Product(s)

siRNA, Antibodies, Proteins, MISSION shRNA Panels, shRNA

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
S192	Anti-SDF-1/PBSF antibody produced in goat affinity isolated antibody, lyophilized powder	human
S2687	Anti-SDF-1β/PBSF antibody produced in goat affinity isolated antibody, lyophilized powder	human
WH0006387M1	Monoclonal Anti-CXCL12 antibody produced in mouse clone 1E5, purified immunoglobulin, buffered aqueous solution	human

Proteins

Product #	Description
S190	Stromal Cell-Derived Factor 1α/pre-B Cell Growth Stimulating Factor human >97% (SDS-PAGE), recombinant, expressed in Escherichia coli, lyophilized powder, cell culture tested
S8406	Stromal Cell-Derived Factor 1β/pre-B Cell Growth Stimulating Factor human >97% (SDS-PAGE), recombinant, expressed in Escherichia coli, lyophilized powder, cell culture tested

MISSION shRNA

Type	Description
SHGLY-NM_000609	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_000609	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_000609	MISSION^® shRNA Plasmid DNA

MISSION shRNA Panels

Product #	Description
SH2211	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock Cell Adhesion Genes
SH2221	MISSION^® shRNA Human Gene Family Set, DNA Cell Adhesion Genes
SH2231	MISSION^® shRNA Human Gene Family Set, Lentiviral Particles Cell Adhesion Genes

siRNA

Click to view price

siRNA ID	RefSeq ID	Approx. siRNA Start	siRNA Type	Ranking
SASI_Hs01_00073752	NM_000609	615	MISSION® siRNA	1
SASI_Hs01_00073753	NM_000609	516	MISSION® siRNA	2
SASI_Hs01_00073754	NM_000609	798	MISSION® siRNA	3
SASI_Hs01_00073755	NM_000609	595	MISSION® siRNA	4
SASI