BMP2 bone morphogenetic protein 2

Activation of PKA through GPCR; Akt Signaling; CREB Pathway; ERK Signaling; GSK3 Signaling; Intracellular Calcium Signaling; JNK Pathway; MAPK Family Pathway; Molecular Mechanisms of Cancer; PAK Pathway; PI3K Signaling; PPAR Pathway; PTEN Pathway; Paxillin Interactions; Rap1 Pathway; SOCS Pathway; STAT3 Pathway; cAMP Pathway; eIF2 Pathway; p38 Signaling; p70S6K Signaling; 14-3-3 Induced Intracellular Signaling; Actin-Based Motility by Rho Family GTPases; Activation of cAMP-Dependent PKA; Airway Pathology in COPD; Apoptotic Pathways in Synovial Fibroblasts; BMP Pathway; Bacterial Meningitis; Cardiomyocyte Differentiation through BMP Receptors; Cellular Apoptosis Pathway; Cellular Immune Responses to HBV; Glucocorticoid Receptor Signaling; Hedgehog Signaling in Mammals; IL-6 Pathway; MIF Mediated Glucocorticoid Regulation; MIF Regulation of Innate Immune Cells; Mitochondrial Apoptosis; NFAT Signaling and Lymphocyte Interactions; Nuclear Receptor Activation by Vitamin-A; PEDF Induced Signaling; PGC1Alpha Pathway; Regulation of eIF4 and p70S6K; Renin-Angiotensin Pathway; SMAD Signaling Network; TGF-Beta Pathway; TOB in Osteoblast Signaling; Tec Kinases Signaling; Telomerase Components in Cell Signaling; all-trans-Retinoic Acid Signaling in Brain; eNOS Signaling;
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Gene and Product Information
BMP2	bone morphogenetic protein 2

Properties

Official Symbol

BMP2

Species

Homo sapiens

Entrez Gene ID

650

Alternate Symbol

BMP2; BMP2A

Refseq ID(s)

NM_001200

Accession No.(s)

BC069214; CR618407; M22489; NM_001200

Protein ID(s)

NP_001191

Homolog(s)

Bmp2(Mouse); Bmp2(Rat)

Function(s)

growth factor/ligand/cytokine/chemokine

Pathway(s)

Activation of PKA through GPCR; Akt Signaling; CREB Pathway; ERK Signaling; GSK3 Signaling; more...

Available Product(s)

siRNA, Antibodies, Proteins, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
WH0000650M2	Monoclonal Anti-BMP2 antibody produced in mouse clone 1A11, purified immunoglobulin, buffered aqueous solution	human
B9553	Monoclonal Anti-Bone Morphogenetic Protein 2 antibody produced in mouse clone 65529.111, purified immunoglobulin, lyophilized powder	human

Proteins

Product #	Description
B3555	Bone Morphogenetic Protein 2 human ≥98% (SDS-PAGE and HPLC), recombinant, expressed in Escherichia coli, lyophilized powder, cell culture tested

MISSION shRNA

Type	Description
SHGLY-NM_001200	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_001200	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_001200	MISSION^® shRNA Plasmid DNA

MISSION siRNA Panels

Product #	Description
SI00100	MISSION^® siRNA Human Druggable Genome Library 6650 targets
SI04100	MISSION^® siRNA Human Gene Family Panels Human Growth Factors/Receptors Panel, 375 targets

siRNA

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siRNA ID	RefSeq ID	Approx. siRNA Start	siRNA Type	Ranking
SASI_Hs01_00016027	NM_001200	1256	MISSION® siRNA	1
SASI_Hs01_00016028	NM_001200	1565	MISSION® siRNA	2
SASI_Hs01_00016029	NM_001200	1317	MISSION® siRNA	3
SASI_Hs01_00016030	NM_001200	1494	MISSION® siRNA	4
SASI_Hs01_00016031	NM_001200	1508	MISSION® siRNA	5
SASI_Hs01_00016032	NM_001200	1178	MISSION® siRNA	6
SASI_Hs01_00016033	NM_001200	917	MISSION® siRNA	7
SASI_Hs01_00016034	NM_001200	1645	MISSION® siRNA	8
SASI_Hs01_00016035	NM_001200	1375	MISSION® siRNA	9
SASI_Hs01_00016036	NM_001200	1645	MISSION® siRNA	10

Sigma's MISSION^® siRNA have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. Critical rules incorporated into the best-in-class Rosetta siRNA design algorithm lead to siRNA of increased target specificity and knockdown for low abundance messages.