BMP5 bone morphogenetic protein 5

Activation of PKA through GPCR; Akt Signaling; CREB Pathway; ERK Signaling; GSK3 Signaling; Intracellular Calcium Signaling; JNK Pathway; MAPK Family Pathway; Molecular Mechanisms of Cancer; PAK Pathway; PI3K Signaling; PPAR Pathway; PTEN Pathway; Paxillin Interactions; Rap1 Pathway; SOCS Pathway; STAT3 Pathway; cAMP Pathway; eIF2 Pathway; p38 Signaling; p70S6K Signaling; 14-3-3 Induced Intracellular Signaling; Actin-Based Motility by Rho Family GTPases; Activation of cAMP-Dependent PKA; Airway Pathology in COPD; Apoptotic Pathways in Synovial Fibroblasts; Bacterial Meningitis; Cardiomyocyte Differentiation through BMP Receptors; Cellular Apoptosis Pathway; Cellular Immune Responses to HBV; Glucocorticoid Receptor Signaling; Hedgehog Signaling in Mammals; IL-6 Pathway; MIF Mediated Glucocorticoid Regulation; MIF Regulation of Innate Immune Cells; Mitochondrial Apoptosis; NFAT Signaling and Lymphocyte Interactions; Nuclear Receptor Activation by Vitamin-A; PEDF Induced Signaling; PGC1Alpha Pathway; Regulation of eIF4 and p70S6K; Renin-Angiotensin Pathway; SMAD Signaling Network; TGF-Beta Pathway; Tec Kinases Signaling; Telomerase Components in Cell Signaling; all-trans-Retinoic Acid Signaling in Brain; eNOS Signaling;
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Gene and Product Information
BMP5	bone morphogenetic protein 5

Properties

Official Symbol

BMP5

Species

Homo sapiens

Entrez Gene ID

653

Alternate Symbol

BMP5; MGC34244

Refseq ID(s)

NM_021073

Accession No.(s)

BC027958; CR605366; M60314; NM_021073

Protein ID(s)

NP_066551

Homolog(s)

Bmp5(Mouse); Bmp5_predicted(Rat)

Function(s)

growth factor/ligand/cytokine/chemokine

Pathway(s)

Activation of PKA through GPCR; Akt Signaling; CREB Pathway; ERK Signaling; GSK3 Signaling; more...

Available Product(s)

siRNA, Antibodies, Proteins, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
B3805	Anti-Bone Morphogenetic Protein 5 antibody produced in goat affinity isolated antibody, lyophilized powder	human
WH0000653M2	Monoclonal Anti-BMP5 antibody produced in mouse clone 1C1, purified immunoglobulin, buffered aqueous solution	human

Proteins

Product #	Description
B9803	Bone Morphogenetic Protein 5 human >95% (SDS-PAGE), recombinant, expressed in mouse NSO cells, lyophilized powder, cell culture tested

MISSION shRNA

Type	Description
SHGLY-NM_021073	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_021073	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_021073	MISSION^® shRNA Plasmid DNA

MISSION siRNA Panels

Product #	Description
SI00100	MISSION^® siRNA Human Druggable Genome Library 6650 targets
SI04100	MISSION^® siRNA Human Gene Family Panels Human Growth Factors/Receptors Panel, 375 targets

siRNA

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siRNA ID	RefSeq ID	Approx. siRNA Start	siRNA Type	Ranking
SASI_Hs01_00133810	NM_021073	1475	MISSION® siRNA	1
SASI_Hs01_00133811	NM_021073	1251	MISSION® siRNA	2
SASI_Hs01_00133812	NM_021073	1256	MISSION® siRNA	3
SASI_Hs01_00133813	NM_021073	1480	MISSION® siRNA	4
SASI_Hs01_00133814	NM_021073	1255	MISSION® siRNA	5
SASI_Hs01_00133815	NM_021073	1418	MISSION® siRNA	6
SASI_Hs01_00133816	NM_021073	1404	MISSION® siRNA	7
SASI_Hs01_00133817	NM_021073	1383	MISSION® siRNA	8
SASI_Hs01_00133818	NM_021073	1240	MISSION® siRNA	9
SASI_Hs01_00133819	NM_021073	1379	MISSION® siRNA	10

Sigma's MISSION^® siRNA have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. Critical rules incorporated into the best-in-class Rosetta siRNA design algorithm lead to siRNA of increased target specificity and knockdown for low abundance messages.