Sigma-Aldrich


Gene and Product Information 
ADAM17 
ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme)
 
Properties
Official Symbol 
 
Species 
Homo sapiens
 
Entrez Gene ID 
 
Alternate Symbol 
ADAM17; CD156B; CSVP; MGC71942; TACE
 
Other Designations 
ADAM metallopeptidase domain 17; TNF-alpha converting enzyme; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); snake venom-like protease
 
Refseq ID(s) 
 
Accession No.(s) 
 
Protein ID(s) 
 
Homolog(s) 
Adam17(Mouse); Adam17(Rat)
 
Function(s) 
protease; protein binding
 
Pathway(s) 
Notch Signaling; Alzheimers Disease Pathway; ErbB4 Pathway; Inhibition of Matrix Metalloproteinases
 
Available Product(s) 

 
Related Products
Product #
Description
Species Reactivity
T5442 Anti-ADAM-17 (TACE), C-Terminal antibody produced in rabbit ~0.5 mg/mL, affinity isolated antibody, buffered aqueous solution human, mouse, rat
A3976 Anti-ADAM-17, Activation Site antibody produced in rabbit ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution human, pig, rat
A4351 Anti-ADAM-17, Cytoplasmic Domain antibody produced in rabbit ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution human, pig, rat
A4226 Anti-ADAM-17, Propeptide Domain antibody produced in rabbit ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution human, pig, rat
HPA010738 Anti-ADAM17 antibody produced in rabbit Prestige Antibodies™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution human
WH0006868M1 Monoclonal Anti-ADAM17 antibody produced in mouse clone 1F6, purified immunoglobulin, buffered aqueous solution human

Type
Description
SHGLY-NM_003183 MISSION® shRNA Bacterial Glycerol Stock
SHVRS-NM_003183 MISSION® shRNA Lentiviral Transduction Particles
SHDNA-NM_003183 MISSION® shRNA Plasmid DNA

Product #
Description
SI00100 MISSION® siRNA Human Druggable Genome Library 6650 targets
SI13100 MISSION® siRNA Human Gene Family Panels Protease Panel, 379 targets

Product #
Description
XP725 Panorama® Antibody Microarray - XPRESS Profiler725 Kit

 
 siRNA

siRNA ID
RefSeq ID
Approx. siRNA Start
siRNA Type
Ranking
SASI_Hs01_00027256 NM_003183 1139 MISSION® siRNA 1
SASI_Hs01_00027257 NM_003183 433 MISSION® siRNA 2
SASI_Hs01_00027258 NM_003183 2754 MISSION® siRNA 3
SASI_Hs01_00027259 NM_003183 2119 MISSION® siRNA 4
SASI_Hs01_00027260 NM_003183 380 MISSION® siRNA 5
SASI_Hs01_00027261 NM_003183 302 MISSION® siRNA 6
SASI_Hs01_00027262 NM_003183 369 MISSION® siRNA 7
SASI_Hs01_00027263 NM_003183