TGFBR1 transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)

Activation of PKA through GPCR; CREB Pathway; MAPK Family Pathway; MAPK Signaling; Molecular Mechanisms of Cancer; PAK Pathway; PI3K Signaling; PPAR Pathway; PTEN Pathway; cAMP Pathway; eIF2 Pathway; p38 Signaling; p70S6K Signaling; Actin-Based Motility by Rho Family GTPases; Apoptotic Pathways in Synovial Fibroblasts; Cellular Apoptosis Pathway; Glucocorticoid Receptor Signaling; IL-2 Gene Expression in Activated and Quiescent T-Cells; Inhibition of Angiogenesis by TSP1; Mitochondrial Apoptosis; NTHi-Induced Signaling; Nuclear Receptor Activation by Vitamin-A; Renin-Angiotensin Pathway; SMAD Signaling Network; Signaling Involved in Cardiac Hypertrophy; TGF-Beta Pathway; TOB in T-Cell Signaling; Telomerase Components in Cell Signaling;
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Gene and Product Information
TGFBR1	transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)

Properties

Official Symbol

TGFBR1

Species

Homo sapiens

Entrez Gene ID

7046

Alternate Symbol

TGFBR1; AAT5; ACVRLK4; ALK-5; ALK5; SKR4; TGFR-1

Other Designations

activin A receptor type II-like kinase, 53kD; activin receptor-like kinase 5; serine/threonine-protein kinase receptor R4; transforming growth factor beta receptor I; transforming growth factor, beta receptor I; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD)

Refseq ID(s)

NM_004612

Accession No.(s)

AJ619019; AJ619020; BC071181; L11695; NM_004612

Protein ID(s)

NP_004603

Homolog(s)

Tgfbr1(Mouse); Tgfbr1(Rat)

Function(s)

growth factor/ligand/cytokine/chemokine receptor; signal transducer; transferase

Pathway(s)

Activation of PKA through GPCR; CREB Pathway; MAPK Family Pathway; MAPK Signaling; Molecular Mechanisms of Cancer; more...

Available Product(s)

siRNA, Small Molecule - Inhibitor, MISSION shRNA Panels, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Small Molecule - Inhibitor

Product #	Description
L6293	LY-364947 ≥98% (HPLC), solid

MISSION shRNA

Type	Description
SHGLY-NM_004612	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_004612	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_004612	MISSION^® shRNA Plasmid DNA

MISSION shRNA Panels

Product #	Description
SHX001	MISSION^® LentiExpress^™ Human Kinases
SH1311	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock Cytokine and Chemokine Receptors
SH0111	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock Kinases
SH1321	MISSION^® shRNA Human Gene Family Set, DNA Cytokine and Chemokine Receptors
SH0121	MISSION^® shRNA Human Gene Family Set, DNA Kinases
SH1331	MISSION^® shRNA Human Gene Family Set, Lentiviral Particles Cytokine and Chemokine Receptors
SH0131	MISSION^® shRNA Human Gene Family Set, Lentiviral Particles Kinases

MISSION siRNA Panels

Product #	Description
SI00100	MISSION^® siRNA Human Druggable Genome Library 6650 targets
SI02100	MISSION^® siRNA Human Gene Family Panels Kinase Panel, 714 targets

siRNA

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siRNA ID	RefSeq ID	Approx. siRNA Start	siRNA Type	Ranking
SASI_Hs01_00181141	NM_004612	1453	MISSION® siRNA	1
SASI_Hs01_00181142	NM_004612	1520	Validated MISSION® siRNA	2
SASI_Hs01_00181143	NM_004612	1171	MISSION® siRNA	3
SASI_Hs01_00181144	NM_004612	383	MISSION® siRNA	4
SASI_Hs01_00181145	NM_004612	1618	MISSION® siRNA	5
SASI_Hs01_00181146	NM_004612	1164	MISSION® siRNA	6
SASI_Hs01_00181147	NM_004612	1362	MISSION® siRNA	7
SASI_Hs01_00181148	NM_004612	656	MISSION® siRNA