TP53 tumor protein p53 (Li-Fraumeni syndrome)

Akt Signaling; Apoptosis through Death Receptors; Cyclins and Cell Cycle Regulation; DNA Repair Mechanism; JNK Pathway; Molecular Mechanisms of Cancer; NGF Pathway; PKR Pathway; PTEN Pathway; TRKA Signaling; WNT Signaling; p53 Signaling; ATM Pathway; Apoptotic Pathways Triggered By HIV1; Apoptotic Pathways in Synovial Fibroblasts; Cellular Apoptosis Pathway; Checkpoint Comparative Pathways; Chks in Checkpoint Regulation; DNA Damage Induced 14-3-3Sigma Signaling; G1-S Phase Transition; G2-M Phase Transition; GADD45 Pathway; HIF1Alpha Pathway; Huntington Disease Pathway; Inhibition of Ribosome Biogenesis by p14(ARF); Inhibition of Ribosome Biogenesis by p19(ARF); MIF Regulation of Innate Immune Cells; Mitochondrial Apoptosis; SUMO Pathway; Telomerase Components in Cell Signaling; UVA-Induced MAPK Signaling; UVB-Induced MAPK Signaling; UVC-Induced MAPK Signaling; c-Myc and Apoptosis;
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Gene and Product Information
TP53	tumor protein p53 (Li-Fraumeni syndrome)

Properties

Official Symbol

TP53

Species

Homo sapiens

Entrez Gene ID

7157

Alternate Symbol

TP53; LFS1; P53; TRP53

Other Designations

p53 tumor suppressor; tumor protein p53

Refseq ID(s)

NM_000546

Accession No.(s)

AB082923; AF307851; AK223026; AK225838; AM076970; more...

Protein ID(s)

NP_000537

Homolog(s)

Trp53(Mouse); Tp53(Rat)

Function(s)

apoptosis; protein binding; transcription factor

Pathway(s)

Akt Signaling; Apoptosis through Death Receptors; Cyclins and Cell Cycle Regulation; DNA Repair Mechanism; JNK Pathway; more...

Available Product(s)

siRNA, Antibody Arrays, Antibodies, Kits, MISSION shRNA Panels, shRNA

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
P4235	Anti-p53 antibody produced in sheep fractionated antiserum, buffered aqueous solution	human, mouse, rat
P8982	Anti-phospho-p53 (pSer³⁹²) antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution	human, mouse
WH0007157M1	Monoclonal Anti-TP53 antibody produced in mouse clone 2C3, purified immunoglobulin, buffered aqueous solution	human
P5813	Monoclonal Anti-p53 antibody produced in mouse clone BP53-12, ascites fluid	human
P6874	Monoclonal Anti-p53 antibody produced in mouse ~2 mg/mL, clone DO-1, purified immunoglobulin, buffered aqueous solution	human
P7874	Monoclonal Anti-p53 antibody produced in mouse ~2 mg/mL, clone DO-2, purified immunoglobulin, buffered aqueous solution	human
P8999	Monoclonal Anti-p53 antibody produced in mouse ~2 mg/mL, clone DO-7, purified immunoglobulin, buffered aqueous solution	human
P6749	Monoclonal Anti-p53 antibody produced in mouse ~2 mg/mL, clone PAb1801, purified immunoglobulin, buffered aqueous solution	human
P9249	Monoclonal Anti-p53−Biotin antibody produced in mouse ~1 mg/mL, clone DO-1, ascites fluid, buffered aqueous solution	human
P9124	Monoclonal Anti-p53−Peroxidase antibody produced in mouse 2-4 mg/mL, clone DO-1, purified immunoglobulin, buffered aqueous solution	human

Kits

Product #	Description
CS0070	p53 ELISA human sufficient for 96 multiwell tests
CS0040	phospho-p53 (pSer¹⁵) ELISA human sufficient for 96 multiwell tests

MISSION shRNA