TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

Akt Signaling; Apoptosis through Death Receptors; JNK Pathway; MAPK Family Pathway; PAK Pathway; PI3K Signaling; SOCS Pathway; STAT3 Pathway; p38 Signaling; Airway Pathology in COPD; Bacterial Meningitis; Cellular Apoptosis Pathway; Cellular Immune Responses to HBV; Glucocorticoid Receptor Signaling; IL-6 Pathway; MIF Mediated Glucocorticoid Regulation; MIF Regulation of Innate Immune Cells; NFAT Signaling and Lymphocyte Interactions; PEDF Induced Signaling; PGC1Alpha Pathway; Regulation of eIF4 and p70S6K; TGF-Beta Pathway; TNF Superfamily Pathway; TRAIL Pathway; Tec Kinases Signaling; all-trans-Retinoic Acid Mediated Apoptosis; all-trans-Retinoic Acid Signaling in Brain;
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Gene and Product Information
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10

Properties

Official Symbol

TNFSF10

Species

Homo sapiens

Entrez Gene ID

8743

Alternate Symbol

TNFSF10; APO-2L; APO2L; CD253; TL2; TRAIL

Other Designations

Apo-2 ligand; TNF-related apoptosis inducing ligand TRAIL

Refseq ID(s)

NM_003810

Accession No.(s)

BC009795; BC020220; BC032722; BT019564; CR456895; more...

Protein ID(s)

NP_003801

Homolog(s)

Tnfsf10(Mouse); Tnfsf10(Rat)

Function(s)

apoptosis; signal transducer

Pathway(s)

Akt Signaling; Apoptosis through Death Receptors; JNK Pathway; MAPK Family Pathway; PAK Pathway; more...

Available Product(s)

siRNA, Antibody Arrays, Antibodies, Kits, Proteins, MISSION shRNA Panels, shRNA, MISSION siRNA Panels

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
T9191	Anti-TRAIL antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution	human
WH0008743M1	Monoclonal Anti-TNFSF10 antibody produced in mouse clone 2E1-1B9, purified immunoglobulin, buffered aqueous solution	human
T3067	Monoclonal Anti-TRAIL antibody produced in mouse clone 75411.11, purified immunoglobulin, lyophilized powder	human

Proteins

Product #	Description
K4761	TRAIL human >95% (SDS-PAGE), recombinant, expressed in Escherichia coli, solution
T5694	TRAIL human recombinant, expressed in mouse NSO cells, >97% (SDS-PAGE), lyophilized powder

Kits

Product #	Description
CS0510	TRAIL ELISA human sufficient for 96 determinations

MISSION shRNA

Type	Description
SHGLY-NM_003810	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_003810	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_003810	MISSION^® shRNA Plasmid DNA

MISSION shRNA Panels

Product #	Description
SH1911	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock Apoptosis Pathway
SH0811	MISSION^® shRNA Human Gene Family Set, Bacterial Glycerol Stock Cytokines and Chemokines