EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa

Gene and Product Information
EIF2B5	eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa

Properties

Official Symbol

EIF2B5

Species

Homo sapiens

Entrez Gene ID

8893

Alternate Symbol

EIF2B5; CACH; CLE; EIF-2B; EIF2BEPSILON; LVWM

Other Designations

eIF-2B GDP-GTP exchange factor; eukaryotic translation initiation factor 2B, subunit 5 (epsilon, 82kD)

Refseq ID(s)

NM_003907

Accession No.(s)

AB208821; AK056400; AK091646; AL832179; BC013590; more...

Protein ID(s)

NP_003898

Homolog(s)

Eif2b5(Mouse); Eif2b5(Rat)

Function(s)

guanyl-nucleotide exchange factor; protein binding; transferase; translation factor

Pathway(s)

GSK3 Signaling; IGF1R Signaling; Insulin Receptor Pathway; eIF2 Pathway; Signaling Involved in Cardiac Hypertrophy

Replaces Gene ID(s)

53364

Available Product(s)

siRNA, Antibodies, shRNA

Useful External Links

NCBI Gene Info.

Compendia Bioscience

Human Protein Reference Database

PubMed

Cytoscape

Gene Expression Tools

Related Products

Antibodies

Product #	Description	Species Reactivity
E7655	Anti-phospho-eIF2Bε (pSer⁵³⁹) antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution	human, rat

MISSION shRNA

Type	Description
SHGLY-NM_003907	MISSION^® shRNA Bacterial Glycerol Stock
SHVRS-NM_003907	MISSION^® shRNA Lentiviral Transduction Particles
SHDNA-NM_003907	MISSION^® shRNA Plasmid DNA

siRNA

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siRNA ID	RefSeq ID	Approx. siRNA Start	siRNA Type	Ranking
SASI_Hs01_00068127	NM_003907	1178	MISSION® siRNA	1
SASI_Hs01_00068128	NM_003907	1277	MISSION® siRNA	2
SASI_Hs01_00068129	NM_003907	993	MISSION® siRNA	3
SASI_Hs01_00068130	NM_003907	1941	MISSION® siRNA	4
SASI_Hs01_00068131	NM_003907	1154	MISSION® siRNA	5
SASI_Hs01_00068132	NM_003907	581	MISSION® siRNA	6
SASI_Hs01_00068133	NM_003907	2337	MISSION® siRNA	7
SASI_Hs01_00068134	NM_003907	2431	MISSION® siRNA	8
SASI_Hs01_00068135	NM_003907	715	MISSION® siRNA	9
SASI_Hs01_00068136	NM_003907	2508	MISSION® siRNA	10

Sigma's MISSION^® siRNA have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. Critical rules incorporated into the best-in-class Rosetta siRNA design algorithm lead to siRNA of increased target specificity and knockdown for low abundance messages.

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