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Hirudin Fragments
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Description
Biochem/physiol Actions
Product #
Ac-Hirudin Fragment 55-65 non-sulfated ≥97% (HPLC)
H9019
Acetyl-
[Tyr(SO
3
H)
63
]-Hirudin Fragment 54-65 ≥95% (HPLC)
H7144
[Tyr(SO
3
H)
63
]-Hirudin Fragment 54-65 ≥95% (HPLC)
Hirudin fragment that binds to the regulatory exosite I on thrombin and the regulatory proexosite I on prothrombin. The interaction with thrombin prevents the thrombin-induced activation of clotting factor V. The interaction with prothrombin inhibits the formation of thrombin by factor Xa in the presence of factor Va.
H6894
Acetyl-
[Tyr(SO
3
H)
63
]-Hirudin Fragment 55-65 ≥97% (HPLC)
H9144
Hirudin Fragment 54-65 non-sulfated ≥97% (HPLC)
Hirudin fragment that binds to the regulatory exosite I (proexosite I) on prothrombin with lower affinity than the sulfated peptide. It inhibits the activation of prothrombin by factor Xa in the presence of factor Va.
H6769
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