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Immunology books

Best Books for the Best Minds

Our Immunology books are the perfect complementary resource to the Antibody Explorer.

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Image	Product #	Book Title	Description
	A0347	Advanced Methods In Cellular Immunology	Immunologists often use protocols involving isolation, culture and characterization of different types of leukocytes. In this collection of techniques, each chapter contains a step-by-step description of the methodology, alternative techniques, pertinent references, and information about commercial sources for materials and reagents. It also includes processes of cell culture as well as inflammation and autoimmunity in animal models. Covering PCR and apoptosis, this book is a guide to common procedures in cellular immunology while utilizing both human and murine models.
	Z374164	Advances in Immunology: Volume 63	The next volume in a series which all immunologists need. This edition features sections on the role of CD40 and its ligand gp39, as central players, in the regulation of Bcell growth and differentiation. A section on prolactin, growth hormone and insulin-like growth factor-I as full-fledged immunological growth and differentiation factors can also be found, as well as many other sections on new and stimulating ideas for immunology.
	Z702579	Antibodies Volume 1: Production and Purification	This book presents an overview of the current advances applied in the manufacture of monoclonal antibodies including concepts in development of manufacturing strategies; importance of antibody fragments; application of chromatography method development; quality control; effect of expression on antibody properties; virus removal and safety; pharmacokinetics; regulatory aspects. Together with Volume 2 (Z70,258-7), these books present a comprehensive account of the current state-of-the-art in the manufacture and application of monoclonal antibodies, and provide an insight into future possibilities.
	A2926	Antibodies: A Laboratory Manual	This book places the production and use of polyclonal and monoclonal antibodies within the reach of every biologist. All of the techniques described are supplemented with extensive notes and two-color illustrations.
	Z368709	Antibody Engineering Protocols	This collection of recently developed methods for producing new antibody reagents by immunization and recombinant DNA techniques contains ready-to-use protocols that illuminate current areas of research on antibody structure, functions and applications. They offer insight into new ways of developing clinically useful antibody reagents.
	Z701858	Antibody Engineering: Methods and Protocols	A collection of techniques for the generation, expression, optimization, and characterization of recombinant antibodies. Reproducible protocols for lead generation range from the cloning of human immunoglobulin genes to the selection and generation of human recombinant antibodies by humanization approaches, molecular display technologies and transgenic animals. Included are procedures on restructuring antibody leads into monovalent, multivalent, and bispecific binding fragments for a variety of in vivo applications. Technologies are described for the characterization of antigen-binding affinity and specificity.
	Z705837	Antigen Presenting Cells: From Mechanisms to Drug Development	This novel, multidisciplinary handbook highlights recent evidence that antigen presenting cells (APCs) are not only key players in the initiation or prevention of an antigen-specific T lymphocyte-mediated adaptive immune response, but also critical regulators and integrators in the interplay between our innate and adaptive immune system. Structured in a clear way to allow access to a very broad readership, the book is written from the viewpoint of a biochemist, immunologist, and scientist with experience in drug development. It covers all cell types involved in antigen presentation, providing the latest immunological facts with a focus on drug development. This short but comprehensive reference covers basic introductory aspects right up to details for advanced specialists.
	A6346	Antigen Processing and Presentation Protocols	Drawing on expertise, investigators describe step-by-step methods designed to question how major histocompatibility complex-binding peptides are generated, to test how peptides are delivered to MHC molecules, to analyze MHC peptide-binding patterns, and to assay the T-cell response to the MHC/peptide complex. Emphasis is given those technical steps critical for experimental success that are often omitted from methods published in the primary literature.
	Z700711	Apoptosis and Autoimmunity: From Mechanisms to Treatments	This is the first comprehensive book about the relationship between apoptosis and autoimmune diseases. It offers a unique up-to-date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies.
	Z703834	Atlas of Immunology, 2nd ed.	With more than 1100 computer-generated figures, line drawings, and photographs, this book clearly demonstrates that "a picture is worth a thousand words." Written for students, basic scientists, and clinicians, this second edition provides a thorough and up-to-date treatment of all the concepts needed to comprehend contemporary immunology. The coverage ranges from photographs of historical figures to molecular structures of recently characterized cytokines, major histocompatibility complex molecules, immunoglobulins, and molecules of related interest. It presents new topics in immunology, molecular structures, and mechanics of molecular and cellular interactions and serves as a valuable aid for surgical pathology through diagnostic immunohistochemistry while including all autoantibodies of significance in diagnostic immunopathology
	B4931	Basic Methods in Antibody Production and Characterization	This manual uses a cookbook approach to presenting the methods for the production, characterization, and use of antibodies. Antibodies described include polyclonal and monoclonal and those made by the phage display. It focuses on specific aspects of antibodies and takes readers on a step-by-step process from antigen preparation to immunizations, adjuvants, screening, purification, storage, and applications. Ample references provide researchers with many applications pertaining to the technology.
	Z703389	Catalytic Antibodies	Exploiting the inherent combinatorial mechanism in the biosynthesis of antibodies, an almost limitless variety of biocatalysts may be generated. Catalytic antibodies are capable of performing almost any type of reaction with high selectivity and stereospecificity. Here, the pioneers in the use of catalytic antibodies review the entire scope of this interdisciplinary field, covering such topics as: theoretical aspects of structure, mechanism and kinetics; practical considerations, from immunization techniques to screening methods; in vitro evolution and other modern approaches; applications from organic synthesis to medical uses. This is the first book to provide such comprehensive coverage and will be the prime reference for biochemists, organic chemists, biotechnologists and biomedical researchers.
	Z730998	Cellular and Molecular Immunology 6th ed.	An exceptionally lucid guide to the latest immunology concepts! Through five best-selling editions, readers worldwide have appreciated this book's in-depth yet straightforward, richly illustrated approach to this complex subject. Now, sweeping updates incorporate the latest discoveries about innate immunity, the organization of lymphoid organs, and many other cutting-edge topics. Plus, online access via STUDENT CONSULT makes this an even more powerful learning resource!
	Z369365	Clinical Immunology: An Illustrated Outline	A succinct review of clinical immunology covering the mechanisms behind disease. It includes examples of diagnostic tests so the reader can find the underlying immunological proceses. The book is organized by key term headings followed by a concise definition. It serves as an illustrated dictionary as well as a review tool.
	C1979	Complement Methods and Protocols	A set of readily reproducible methods and cutting-edge techniques is directed to those interested in understanding complement’s mechanisms of activation and to those wishing to quantify its activation, and range from the purification of its components to generating complement-deficient mice by gene deletion. Additional techniques include procedures for the analysis of its function, for the study of its regulators, for detection of its activation in vivo, and for the identification of its autoantibodies.
	Z700436	Cytokine Factsbook and Webfacts, 2nd ed.	This second edition is the most up-to-date reference manual available for all well-characterized interleukins, cytokines, and their receptors. An additional 52 cytokines are included, doubling the number of entries from the previous edition. The key properties of each cytokine are described and presented in a very accessible format with diagrams for each of the receptors. It includes free online access to Cytokine Webfacts. Cytokine Webfacts is a web-based compendium of facts about cytokines and their receptors that includes a variety of data representations, such as text, signal pathway diagrams and 3D images.
	Z701629	Cytokine Handbook, 4th ed. 2 volume set	The fourth edition provides encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes with contributions from more than 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for anyone interested in cytokines and working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics.
	C2606	Cytokine Molecular Biology: A Practical Approach	This manual concentrates on molecular biology techniques for the study of cytokines, cytokine receptors, and cytokine driven processes. Topics include the cloning and expressing of cytokine genes, the analysis of cytokine mRNA by RT-PCR, cDNA array systems and in situ hybridization, the study of cytokine gene polymorphisms, the analysis of cytokine signaling via PC-specific phospholipase C and sphingomyelinases, the Jak/STAT and MAPK signaling pathways, and gene modification in transgenic and mutant mice.
	C2479	Cytokine Network	Cytokines act in a complex network where one cytokine can influence production of, and response to other cytokines. This book covers the study of cytokine and cytokine receptor structure, elucidation of convergent intracellular signaling pathways, molecular genetics, and targeted gene disruption to 'knock-out' production of individual cytokines in mice. It is not a survey of individual cytokines, but a guide to the cytokine network covering genomics, signaling pathways, control of the immune response, and therapeutics.
	Z730637	Diagnostic Immunohistochemistry 2nd ed.	The New Edition of this popular text features world-renowned experts who offer the most current information and reliable guidance on immunohistochemical diagnoses in surgical pathology and cytopathology. The book is organized in a consistent format of organ systems, specifically designed to target diagnostic dilemmas in surgical pathology. Each chapter features an introduction and a systematic approach to the diagnostic entities of that organ system. Readers will also find easy-to-understand diagnostic algorithms and "immunohistograms" that depict immunostaining patterns of tumors, as well as charts, tables, and high-quality color histologic images that assist in making a definitive diagnosis
	E2027	ELISA Guidebook	This is today's premier practical guide to the understanding and application of ELISA. Updating Crowther's publication, ELISA Theory and Practice (1995), this book introduces chapters on such major new topics as checkerboard titrations, quality control of testing, kit production and control, novel monoclonal antibodies, validation of assays, statistical requirements for data examination, and epidemiological considerations. It contains numerous worked examples, detailed instructions, and extensive illustrations.
	Z370258	Enzyme Immunoassays: From Concept to Product Development	A vertical exposition of enzyme immunoassays; the intended audience is product designers and R&Dgroups who aim to commercialize EIA technology. From concepts of antibody and antigen through laboratory development, all the way to manufacturing, marketing, and regulatory compliance, the book is a practical resource for the diagnostic field.
	Z373990	Epitope Mapping Protocols: Methods in Molecular Biology, Vol. 66	This manual offers more than thirty protocols for antibody production and mapping. Methods range from those that use (or can use) whole, native antigens to those that require antigen expressed from recombinant DNA. Methods for T-cell epitopes and techniques for producing panels of antibodies for epitope mapping are also included.
	E4527	Epitope Mapping: A Practical Approach	This book covers major methods for identification and definition of epitopes. Pepscan assay is used to define B cell epitopes and makes use of synthetic peptides. Site directed mutagenesis is a powerful tool and can be used to evaluate the role of single amino acids in immune complex formation. Protein footprinting relies on the fact that the epitope is protected from cleavage when bound as an antibody-antigen complex. Random phage display libraries can be screened with antibody and resulting DNA sequenced to confirm the amino acid sequence of a specific epitope.
	E4152	Essential Immunology, 10th ed.	Roitt's Essential Immunology is regarded as 'the best of the immunology primers' and the tenth edition text remains at the cutting edge. Investigators find Roitt's book a lifeline to prevent drowning in an ocean of immunological jargon. This edition is completely updated throughout and places greater emphasis on core knowledge & ease of use. It highlights cell signaling pathways, chemokines and their receptors, activation-induced cell death, DNA vaccines, and molecular understanding of immunodeficiency. The book is supported by a web site at www.roitt.com.
	Z702862	Flow Cytometry Protocols 2nd ed.	These reproducible methods deploy emerging flow cytometry technologies in many applications. Here, the aspiring investigator will find methods for the characterization of stem/progenitor cells by monitoring the efflux of fluorescent dyes and the elucidation of signal transduction pathways using phospho-specific antibodies. There are also techniques for monitoring gene transfer and expression using fluorescent protein technology, high throughput screening for discovery of novel protein interactions, phenotypic and functional characterization of T cell subsets and precursors, and microbial flow cytometry.
	F1049	Flow Cytometry: A Practical Approach, 3rd ed.	This is a handbook for every laboratory that has a bench-top flow cytometer or a fluorescence activated cell sorter. It is a guide for those new to the field and a first point of reference for experienced practitioners who want to investigate a new technique. Flow cytometry has found increasing application in the field of apoptosis research, and a new chapter has been added to cover this important topic.
	F0178	Flow Cytometry: First Principles, 2nd ed.	With advances in flow cytometry, this edition provides an update, reflecting innovations while outlining the fundamental elements of instrumentation, sample preparation, and data analysis. It explains the basic principles of flow cytometry, surveys scientific and clinical applications and highlights state-of-the-art techniques. This edition contains revisions of all chapters with new discussions on fluorochrome and laser options for multicolor analysis, an additional section on apoptosis in the chapter on DNA, and new chapters on intracellular protein staining and cell sorting, including high-speed sorting and alternative sorting methods, as well as traditional technology.
	G2793	Gold and Silver Staining: Techniques in Molecular Morphology	Immunogold silver staining is one of the most sensitive techniques for visualizing the location of antibodies and nucleotide probes. Contributors cover the latest developments and a range of applications from highly sensitive detection of antigens to single copy detection of DNA and RNA. This book presents descriptions that allow visualization of molecules never localized before. It also provides a selection of protocols with high sensitivity; presents techniques for cytochemistry, histochemistry, in situ hybridization, and immunoblotting applications; discusses the applications to cancer research; offers suggestions, tips, and guidelines to avoid unspecific precipitations; analyzes advantages and drawbacks of staining methods.
	Z704164	Handbook of ELISPOT: Methods and Protocols	In this book on ELISPOT, a critical enzyme-linked immunospot assay, experts detail how to design, perform, and analyze these assays. The techniques cover a wide variety of topics, including the use of membrane-backed plates, the standardization and validation procedures, the removal of cells from ELISPOT plates, cell separation techniques, and the quantification of ELISPOT data. There are also numerous ELISPOT applications involving animal models, human cells, measles, multiple sclerosis, immune responses, multicytokine detection systems, and immunocytochemistry. Highlights include dual-color and multiplex ELISPOT assays, use of the ELISPOT assay on feline lymphocytes, standardization of the ELISPOT procedure, and combining the ELISPOT assay with immunohistochemistry.
	Z375632	Handbook of Human Immunology	This book provides a complete guide to molecular immunology. The basic principles underlying assays of the immune system are discussed as are the application and interpretation of immune tests. It emphasizes the molecular basis for induction and regulation of immune responses; discusses cell receptors and accessory molecules, cytokines, growth factors and interleukins and their application in the diagnosis of various diseases; reviews serological testing for infectious diseases and the application of molecular biological techniques; and 115 tables summarize textual information.
	Z704059	Illustrated Dictionary of Immunology, 2nd ed.	Immunologists have always maintained a unique nomenclature that has mystified and even baffled their colleagues in other fields, causing them to liken immunology to a "black box." With more than 1,200 illustrations that depict every concept of importance, this second edition provides immunologists and nonimmunologists alike a single-volume resource for the many terms encountered in contemporary immunological literature. Encyclopedic in scope, the content ranges from photographs of historical figures to molecular structures of recently characterized cytokines, the major histocompatibility complex molecules, immunoglobulins, and molecules of related interest to immunologists. Since the first edition, there has been an exponential increase in immunological information and this text represents these advances.
	Z705713	Immune Response: Basic and Clinical Principles	The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences. Includes a CD-ROM containing all the figures and plates appearing in the book.
	Z373672	Immunoassay	An indispensable guide to information on the theory and practice of immunoassays. This book balances the content among theory, practical issues, quality control, automation, and subspecialty areas. Protocols for specific assays are included.
	Z704040	Immunoassay Handbook, 3rd ed.	This third edition offers a balanced review of practical information and clinical applications in the field of immunoassay technology. Comprehensive and expertly written, this handbook will be invaluable for a wide range of users from researchers developing immunoassay systems to developmental and marketing staff who need an excellent overview of how immunoassay principles, systems and applications work. With 68 chapters covering a wide range of topics, and new chapters looking at: surface plasmon resonance in kinetic, concentration and binding site analyses, and the foundations of immunochemistry, this handbook is a must read for all laboratory researchers and academics who use immunoassay as a tool.
	I7893	Immunoassays: A Practical Approach	This is designed to help biologists develop an immunoassay of any common format for any suitable analyte. The basic principles are described and the choices of assay types and formats listed. Methods for raising and for characterizing antibodies, for preparing radioactive, enzymatic, fluorescent and other labels, are described. Solid-phase reagents, standards and immunogens are explained, with procedures for their preparation. Most components can now be obtained commercially.
	Z702765	Immunobiology:The Immune System in Health and Disease, 6th ed.	This text guides the reader through the immune system from the first engagement of innate immunity to the generation of the adaptive immune response and its clinical consequences. The order of topics has been altered to place related material together. Each chapter has been updated to incorporate new observations that extend our knowledge and understanding of the immune system. Immunobiology 6 Interactive, a CD-ROM packaged with the book, contains every figure in the text, and animations and videos with voiceover narration.
	Z703281	Immunochemical Protocols, 3rd ed.	This new edition of a much praised classic includes both basic method for producing and using antibodies and advanced techniques required by today's state-of-the art investigators. The basic sections of the book stress the first principles of antibody production and guide the reader through the processes and pitfalls of immunochemistry. The advanced sections focus on specific applications and cover the immunochemical techniques now used in laboratories. New material includes techniques for making new monoclonal cell lines, for producing good quality monoclonal antibodies, immunocapture PCR, immunoaffinity purification, and immunoelectron microscopy in plant virus diagnosis.
	I5653	Immunocytochemical Methods and Protocols, 2nd Edition	This 2nd edition revises and updates the previous collection of step-by-step immunocytochemical methods now used in many biological and biomedical research programs. The methods are designed for researchers and clinicians that wish to visualize molecules in plant or animal embryos, tissue sections, cells, or organelles. In addition to cutting-edge protocols for purifying and preparing antibodies, light microscopic analysis, confocal microscopy, FACS, and electron microscopy are also covered.