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Z718602 A to Z of DNA Science: What Scientists Mean When They Talk about Genes and Genomes Medical science constantly demands our attention, as patients or relatives, concerned citizens, voters, investors, or simply curious individuals. But for those without training, the language of science is often hard to follow. The A to Z of DNA Science book series defines and illustrates specialized terms in ways that non-specialists can appreciate and enjoy. This volume focuses on the language of genes, genomes, DNA, biotechnology, and heredity, defining, explaining, and illustrating over 200 terms used in books, broadcasting, websites, and newspaper and magazine articles
Z718769 A to Z of DNA Science: What Scientists Mean When They Talk about Genes and Genomes Medical science constantly demands our attention, as patients or relatives, concerned citizens, voters, investors, or simply curious individuals. But for those without training, the language of science is often hard to follow. The A to Z of DNA Science book series defines and illustrates specialized terms in ways that non-specialists can appreciate and enjoy. This volume focuses on the language of genes, genomes, DNA, biotechnology, and heredity, defining, explaining, and illustrating over 200 terms used in books, broadcasting, websites, and newspaper and magazine articles.
Z702439 A-Z of Quantitative PCR This is not just a cookbook for real-time quantitative PCR (qPCR). Admittedly, there are lots of recipes from distinguished contributors and Bustin has attempted to collect, sift through and rationalize the vast amount of information that is available on this subject. And yes, this book was conceived as a comprehensive hands-on manual to allow both the novice researcher and the expert to set up and carry out qPCR assays from scratch. However, this book also sets out to explain as many features of qPCR as possible, provide alternative viewpoints and methods and, perhaps most importantly, aims to stimulate the researcher into generating, interpreting and publishing data that are reproducible, reliable and biologically meaningful.
Z702595 A-β Metabolism and Alzheimer’s Disease This book explores the aggregation of amyloid-β peptide in the brain which plays a primary role in the pathogenesis of Alzheimer’s disease. It provides current information regarding generation, degradation within the brain, and transport out of the brain.
Z541923 ACD/Boiling Point Pro Academic ACD/Boiling Point Pro allows you to predict the boiling point for a compound over a wide range of pressures. You can also calculate vapor pressure as a function of temperature, the enthalpy of vaporization, and the flash point.
Z536539 ACD/NMR Processor Commercial ACD/NMR Processor enables you to take raw NMR data directly from the spectrometer, using any of the key spectrometer formats and process it using a wide range of tools, including peak fitting and automatic Jcoupling analysis.
• Import a wide variety of NMR data formats (including ACD spectrum, Galactic, JCAMP, JEOL, Lybrics, Nicolet ®, Nuts32, TECMAG, UX_NMR, VNMR, and WinNmr)
• JCAMP export of structure, spectra, and tables of assignment and peaks
• Full audit trail feature (History) tracks every applied processing command
• Zero filling, weighting functions, FID shift, Fourier transform
• Zoom, phase correction, baseline correction, peak picking, and spectrum integration functions
• Construction of table of multiplets and coupling constants
• Various spectral editing tools
• Addition and subtraction of two spectra
• Ability to attach chemical structures to a spectrum
• Text annotation of peaks and regions of interest in spectrum
• Preparation of high quality reports including spectra, structures, annotations and tables using full integration with ACD/ChemSketch

Z730076 ACS Style Guide: Effective Communication of Scientific Information, 3rd ed. This extensive revision of The ACS Style Guide thoroughly examines electronic tools now available to assist STM writers in preparing manuscripts and communicating with publishers. Valuable updates include discussions of markup languages, citation of electronic sources, online submission of manuscripts, and preparation of figures, tables, and structures. This edition also contains references to many resources on the internet. With this wealth of new information, this edition continues its long tradition of providing invaluable insight on ethics in scientific communication, the editorial process, copyright, conventions in chemistry, grammar, punctuation, spelling, and writing style for any STM author, reviewer, or editor. This is the definitive source for all information needed to write, review, submit, and edit scholarly and scientific manuscripts.
Z369926 ASM Pocket Guide to Clinical Microbiology, 2nd ed. Completely revised, updated, and expanded, the Pocket Guide to Clinical Microbiology, 2nd Edition will help you and your busy
laboratory associates quickly locate answers to the most commonly asked questions you encounter in your daily interactions with physicians and other members of the health care team. As an added feature, the Pocket Guide presents a uniform approach to the taxonomy of the organisms, clearly showing the relationships among the many clinically relevant microbes. Data are presented in clear charts, diagrams and figures.
Z718831 Abraham Lincoln’s DNA and Other Adventures in Genetics Twenty-four true, wide-ranging tales of crime, history, human behavior, illness, and ethics, told from the personal perspective of the author, an eminent physician-lawyer who uses the stories to illustrate the principles of human genetics and to discuss the broader issues.
Z552178 Absorbable and Biodegradable Polymers Interest in biodegradable and absorbable polymers is growing rapidly in large part because of their biomedical implant and drug delivery applications. This text illustrates creative approaches to custom designing unique, fiber-forming materials for equally unique applications. It includes an example of the development and application of a new absorbable system, a condensed encyclopedia on novel PEG-based copolyesters, and the first comprehensive discussion of a novel class of absorbable tissue adhesives. The book also provides up-to-date information on important tissue engineering technologies and approaches to utilizing these technologies for long awaited practical applications.
Z701386 Absorption and Drug Development: Solubility, Permeability, and Charge State Many times drugs work fine when tested outside the body, but in the body they fail. One of the major reasons is that the drug cannot be absorbed. This book shows readers how to examine a compound's pharmaceutical properties, emphasizing oral absorption. It explains the different physicochemical methods used to analyze drug candidates and how to interpret these methods. This book also helps drug discovery professionals to eliminate poorly absorbable molecules early in the drug discovery process, which can save drug companies millions of dollars. Also included are physicochemical data for over 200 commercial drugs.
A9718 Actin This book describes actins as highly conserved proteins found in virtually all eukaryotic cells. They have prolific roles in cell motility, from the contraction of striated muscle to the movement of organelles within cells, and are known to interact with a diverse number of proteins. This edition gives a comprehensive account of actin sequence, mutation, and structure as well as providing insight into ligand-binding sites and drug and toxin binding.
A7226 Adenoviral Vectors for Gene Therapy This book provides detailed, comprehensive coverage of the gene delivery vehicles based on the adenovirus, which are important tools for gene therapy. These new therapeutic agents have great potential in the treatment of disease. The topics covered in this book range from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology and the use of adenoviral vectors in preclinical animal models, to regulatory issues which must be considered prior to the initiation of human clinical gene therapy trials. The broad scope provides a complete understanding of the development and use of adenoviral vectors.
A2594 Adenovirus: Methods and Protocols A cutting-edge collection of readily reproducible methods for conducting research with adenoviruses, the premier and most widely used model in cell and molecular biology. The methods range from how to grow and titer adenoviruses and how to construct specific alterations in the adenovirus genome, to how to measure apoptosis induced by cells of the immune system, cytokines, and intrinsic apoptosis effectors. In addition, there are methods to study transcription and splicing with in vitro systems and for the adenovirus-mediated transformation of cells to a malignant state.
A9721 Adhesion Molecule Factsbook, 2nd ed. Second Edition is completely updated, and expanded to reflect new advances. It contains over 80 entries on all currently cloned and characterized cell adhesion molecules, including the families of integrins, cadherins, selectins, members of the immunoglobulin superfamily, and other relevant receptors. It provides information on amino acid sequence of the most commonly studied organisms; gene organization and chromosomal location; alternative nomenclature; biological function; tissue distribution; disease association; database accession numbers.
A2719 Adhesion Protein Protocols The cutting edge methods in this title will enable both novice and experienced researchers readily to identify and clone new adhesion proteins, to successfully produce inhibitors of the adhesive activity, to develop biological models for the assay of cell-to-matrix and cell-to-cell adhesion in vitro, and to measure the signaling activities of adhesion proteins. By illuminating these adhesive molecules and the possibilities for manipulating them, the new experimental strategies collected here will have considerable clinical potential for the regulation of immunity, inflammation, tissue remodeling, and embryonic development.
Z705187 Adrenergic Receptors in the 21st Century An authoritative review of the current state-of-the-art understanding of the structure and function of the adrenergic receptor subtypes, as well as of the role played by these receptors in physiological and pathophysiological settings. Topics range from structure-function studies and the imaging of adrenergic receptors to the use of genetically altered mouse models and pharmacogenomics. Highlights include a survey of the knockout and overexpressed mouse models, a review of the new ways that adrenergic receptors can signal, and the effects of polymorphisms on clinical outcomes and on potential gene therapy applications. The side-by-side comparison of all the adrenergic receptors (a1, a2, and b) provides the reader with an excellent survey of the field, including the rationale for designing better drugs to control blood pressure and heart function.
Z555789 Adsorbents: Fundamentals and Applications Covers the explosion in the development of new nanoporous materials thoroughly, as the adsorption properties of some of these materials have remained largely unexplored. The whole of the text benefits from the new adsorbent designs made possible by the increase in desktop computing and molecular simulation, making Adsorbents useful to both practicing laboratories and graduate programs.
Z703036 Adult Stem Cells This comprehensive review of our current understanding of adult stem cell types and their regulation examines the derivation, characterization, and utility of adult stem cells found in skeletal muscle, dental pulp, prostate, kidney, the eye, inner ear, and other tissues. The authors pay special attention to adult stem cell plasticity and their utility in normal tissue homeostasis, as well as their applications in regenerative medicine.
Z282626 Advanced Asymmetric Synthesis Asymmetric synthesis is one of the most critical strategic subjects in organic chemistry, and this book describes advanced techniques and their applications to the industrial and laboratory synthesis of important chiral molecules. The international team of highly respected authors provide rigorous and concise reviews of their areas of expertise.
Z286354 Advanced Catalysts and Nanostructured Materials: Modern Synthetic Methods This book seeks to provide a modern, materials science account of the best and most current techniques for the synthesis of advanced catalytic materials. Until now, there has been no single book which contains a definitive and comprehensive description of the important technologies for catalyst synthesis within the context of modern materials science. Although the emphasis is on new synthetic techniques for catalytic applications, the book presents all of the important technologies for the fabrication of electronic and structural ceramics, and superconductors.
Z412457 Advanced Inorganic Chemistry, 6th ed. For more than a quarter century, Cotton and Wilkinson's Advanced Inorganic Chemistry has been the source that students and professional chemists have turned to for the background needed to understand current research literature in inorganic chemistry and aspects of organometallic chemistry. Like its predecessors, this updated Sixth Edition is organized around the periodic table of elements and provides a systematic treatment of the chemistry of all chemical elements and their compounds. It incorporates important recent developments with an emphasis on advances in the interpretation of structure, bonding, and reactivity.
A0347 Advanced Methods In Cellular Immunology Immunologists often use protocols involving isolation, culture and characterization of different types of leukocytes. In this collection of techniques, each chapter contains a step-by-step description of the methodology, alternative techniques, pertinent references, and information about commercial sources for materials and reagents. It also includes processes of cell culture as well as inflammation and autoimmunity in animal models. Covering PCR and apoptosis, this book is a guide to common procedures in cellular immunology while utilizing both human and murine models.
Z536741 Advanced Organic Chemistry, 4th ed. Part A: Structure and Mechanisms Part A emphasizes quantitative and qualitative description of structural effects on reactivity and mechanism.
The Fourth Edition provides updated material but continues the essential elements of the previous edition. The material in Part A is organized on the basis of fundamental structural topics such as structure, stereochemistry, conformation and aromaticity and basic mechanistic types. The material in Part B is organized on the basis of reaction type with emphasis on reactions of importance in laboratory synthesis. The two parts stand alone, although there is considerable cross-referencing. This edition updates certain topics that have advanced rapidly in the decade, including computational chemistry, structural manifestations of aromaticity, enantioselective reactions and lanthanide catalysis.
Z528935 Advanced Organic Chemistry, 4th ed. Part B: Reaction and Synthesis Part B emphasizes the most general and useful synthetic reactions. The focus is on the core of organic chemistry, but the information provided forms the foundation for future study and research in medicinal and pharmaceutical chemistry, biological chemistry and physical properties of organic compounds.
The Fourth Edition provides updated material but continues the essential elements of the previous edition. The material in Part A is organized on the basis of fundamental structural topics such as structure, stereochemistry, conformation and aromaticity and basic mechanistic types. The material in Part B is organized on the basis of reaction type with emphasis on reactions of importance in laboratory synthesis. The two parts stand alone, although there is considerable cross-referencing. This edition updates certain topics that have advanced rapidly in the decade, including computational chemistry, structural manifestations of aromaticity, enantioselective reactions and lanthanide catalysis.
Z513725 Advanced Organic Chemistry: Reaction Mechanisms A best-selling mechanistic organic chemistry text in Germany, this text's translation into English fills a long-existing need for a modern, thorough and accessible treatment of reaction mechanisms for students of organic chemistry at the advanced undergraduate and graduate level.
Z730394 Advanced Technologies in Biopharmaceutical Processing An increasing number of pharmaceuticals in human and veterinary medicine are being developed using advanced genetic and other methods that focus on modification of somatic and embryonic cells. These methods call for new processes that go beyond the traditional unit processes of chemical and biological production. This book is the first to describe these advanced biological processes and show how they are applied to the production of biopharmaceuticals, from product generation and purification to fill-finish operations. The work explains how these technologies function similarly to unit operations for producing advanced biopharmaceuticals, such as hormones, modified proteins, etc. From large-scale animal cell bioreactors to patient-customized products, this volume guides users on how to apply new technologies in process development.
Z555681 Advances in Controlled/ Living Radical Polymerization Presents new developments in controlled/living radical polymerization in three areas: atom transfer radical polymerization (ATRP), nitroxide mediated polymerization (NMP), and reversible addition-fragmentation transfer (RAFT). This book also includes synthesis and characterization of many new materials.
Z374105 Advances in Genetics: Volume 34 This volume focuses on the polytene chromosome in three parts: morphology and structure, organization and function, and transcription patterns and replication. Includes more than 100 figures and 2900 references.
Z374164 Advances in Immunology: Volume 63 The next volume in a series which all immunologists need. This edition features sections on the role of CD40 and its ligand gp39, as central players, in the regulation of Bcell growth and differentiation. A section on prolactin, growth hormone and insulin-like growth factor-I as full-fledged immunological growth and differentiation factors can also be found, as well as many other sections on new and stimulating ideas for immunology.
Z702226 Affinity Capillary Electrophoresis in Pharmaceutics and Biopharmaceutics This reference presents recent breakthroughs and techniques in affinity capillary electrophoresis (ACE) to measure and determine the physicochemical and thermodynamic parameters of drug compounds—offering strategies to explore and characterize interactions between drugs, drug vehicles, and biological membranes to facilitate developments in controlled drug delivery and targeting. This book contains current applications and procedures to identify binding constants between drugs, biological structures, proteins, nucleic acids, and plasmids; increase drug bioavailability; enhance the permeability, solubility, strength, and function of drug formulations; examine protein-protein exchanges and reactions; calculate pKa values.
A9595 Affinity Chromatography: Methods and Protocols The methods detailed range from immunoaffinity chromatography to state-of-the-art phage-display technology in the discovery of affinity ligands and drugs. Included are reproducible separations of such small molecules as haptens, protein ligands, and supramolecular structures. Each chapter is devoted to a specific technique and includes step-by-step instructions. Practical notes suggest alternative procedures and describe how to overcome problems that may occur.
Z378127 Affinity Separations: A Practical Approach This small, accessible volume covers a remarkable range of techniques for affinity-based purification. Separate chapters are devoted to purification of proteins, nucleic acids, and oligosaccharides. Immunoaffinity applications and the use of affinity tags for recovering recombinant proteins are also thoroughly covered. Even affinity-based cell sorting receives a chapter. This is a practical reference for everyday use.
A5847 Affinity and Immunoaffinity Purification Techniques Application of affinity and immunoaffinity ligands is an essential aid in the selective isolation of specific analytes. Techniques have nuances, such as ligand orientation, ligand stability, and bound analyte recovery, that can hinder successful isolation of the desired material and result in suboptimal or nonrecovery. Other reasons for failure are that separation science approaches an art form, and that tricks essential for success are lost in the text or missing from published articles. This is a sound guide for those wishing to use these techniques in their experimental designs.
Z730467 Alcamo's Fundamentals of Microbiology, 8th ed. The eighth edition provides a firm foundation in microbiology with an emphasis on human disease. It is written for students in nursing and allied health programs. This edition revised by award winning educator Jeffrey Pommerville, retains the late Ed Alcamo’s student friendly style. Microbiology is a rapidly advancing and dynamic discipline. Dr. Pommerville presents new content on recent discoveries, such as information on the avian flu and the 2006 Midwest mumps outbreak, in a manner that is directly applicable to students. Dr. Pommerville also integrates new teaching pedagogies, based on his years of teaching experience, to promote problem-based learning and facilitate mastery of concepts.
Z406716 Aldrich® CH109™ Chemical Calculator on 31/2 in. diskette This program functions not only as an advanced scientific calculator, but also calculates molecular weights, % C, % H, % isotope, and many other calculations. It handles complex expressions, chemical and biochemical abbreviations, and offers users the benefit of speed and accuracy in chemical, peptide, and isotope calculations.
Z547522 Aldrich® FT-IR library, single user Galactic format Contains 11,000 FT-IR spectra of pure compounds.
Z231037 Aldrich® Library of 13C and 1H FT-NMR Spectra This three volume set of 12,000 high-resolution 75MHz 13C and 300MHz 1H FT-NMR spectra is arranged according to functionality.
Z286001 Aldrich® Library of FT-IR Spectra, 2nd ed., 3-volume set This three volume set includes over 18,000 spectra categorized by chemical functionality and arranged in order of increasing structural complexity. All spectra were run in the Aldrich quality control laboratories and confirmed by other spectroscopic and chromatographic analyses. The library includes extensive cross-references by chemical name, molecular formula, CAS number, and Aldrich catalog number.
Z180009 Aldrich® Library of FT-IR Spectra: Vapor Phase, Volume 3 This volume features 6,550 vapor phase spectra.
Z107506 Aldrich® Library of Infrared Spectra, 3rd Ed.