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Image	Product #	Book Title	Description
	Z271500	Quality in the Analytical Chemistry Laboratory	Introduces the whole concept of quality assurance and implementation. Discusses how sampling, method selection, equipment, and taking measurements affects the quality of analytical data.
	Z705640	Quantitative Applications of Mass Spectrometry	This text presents the information needed to design a successful quantitative analysis using mass spectrometric techniques currently available and widely employed. It is devoted to the researchers of different areas, who use mass spectrometry as a detector suitable for the measurements of their interest. An essential book for the practicing mass spectroscopist and a genuine 'how-to' text for the practitioner focusing on quantification rather than instrumental design and techniques. It contains up-to-date structured text describing methods, experimental strategy, capabilities and limitations, with data analysis and interpretation and it brings together material widely dispersed in the pertinent literature into one unique source.
	Q4254	Quantities, Symbols, Units, and Abbreviations in the Life Sciences: A Guide for Authors and Editors	This book provides easy access to universally accepted symbols, units, abbreviations, and measures of quantity for your scientific communications in the life sciences. Drawing on the authority of the various nomenclatural committees of the many international societies in bioscience, as well as on the editors of prestigious scientific journals, and on eminent individuals active in scientific publishing, Arnost Kotyk brings together the most up-to-date recommendations for using units, symbols, abbreviations, and acronyms in the biosciences.
	Z550140	Quantum Dots and Nanowires	Provides coverage on various emerging aspects of quantum dots and nanowires. Covers recent advances in physical and chemical synthetic approaches, processing and fabrication of semiconductor quantum-dot arrays, superlattices, self-assemblies, nanowires, nanotubes and nanobelts, computational modeling approaches, spectroscopic characterization, their unique electrical, optical, magnetic and physical properties associated with size effect, transport phenomena, quantum computing and other potential applications.
	Z705349	Quest for Consciousness: A Neurobiological Approach	Consciousness is the major unsolved problem in biology. How do the elemental feelings and sensations making up conscious experience, the redness of red and the painfulness of pain, arise from the concerted actions of nerve cells and their associated synaptic and molecular processes? Can such feelings be explained by modern science, or is some different kind of explanation needed? And how can this seemingly intractable problem be approached experimentally? Designed as an introduction to the field and drawing upon anatomical, physiological, clinical and psychological observations, this book seeks answers to these questions with a neurobioloigcal framework; that is, how do the operations of the conscious mind emerge out of the specific interactions of myriads of neurons?
	R5152	RNA Editing	This book devotes a chapter to each of the major types of this form of RNA processing. Each chapter offers fundamental principles, as well as up to date information on recent advances. Numerous examples of RNAs known to be edited are provided throughout and the book highlights the mechanistic diversity found among the various types of RNA editing. RNAs are cleaved, ligated, and deaminated on their way to maturation, and in some cases, their sequence is even altered in the brief moment when RNA polymerase stalls. The chemical reactions that allow RNA editing, and the RNA and proteins that direct the process are all described.
	Z703346	RNA Interference in Practice	This hand-on guide to RNA interference makes the power of targeted gene silencing available to any laboratory with a basic equipment for the handling of nucleic acids. In easy to follow step-by-step protocols you will learn: * How RNAi works in plants, flies and mammals * How to design the most efficient RNAi constructs * How to achieve transient, stable and conditional RNAi in cell cultures * How to determine the efficiency of an RNAi experiment * How to use RNAi for gene therapy. All protocols have been thoroughly tested in the author's laboratory. Examples of successful experiments and troubleshooting hints are provided to help in establishing your own successful RNAi experiments.
	Z702730	RNA Interference, Editing, and Modification: Methods and Protocols	A comprehensive collection of cutting-edge methods for elucidating the function of new genes and altering gene expression. These readily reproducible techniques can be used either in transient and stable gene splicing applied to worms, flies, trypanosomes, mammals, and plants, or in studying RNA editing mechanisms in a wide range of organisms, including systems that involve the conversion of one base to another and insertion/deletion editing. Topics of interest include stable and transient RNA interference, gene silencing, RNA editing, bioinformatics, small noncoding RNAs, and RNomics.
	R1025	RNA Isolation and Characterization Protocols	Innovative biological investigators offer a powerful and highly useful collection of up-to-date methods for the isolation of RNA from a variety of sources, including bacterial, plant, and mammalian cells. These fine-tuned protocols take both the experienced and inexperienced investigator through the nuances of RNA manipulation, from extraction to in vitro translation. The book also includes protocols for the analysis and characterization of isolated RNA species and extensive troubleshooting hints and tips to ensure easy reproducibility.
	Z704490	RNA Methodologies: A Laboratory Guide for Isolation and Characterization, 3rd ed.	This laboratory guide represents a growing collection of tried, tested and optimized laboratory protocols for the isolation and characterization of eukaryotic RNA, with lesser emphasis on the characterization of prokaryotic transcripts. Collectively the chapters work together to embellish the RNA story, each presenting clear take-home lessons, liberally incorporating flow charts, tables and graphs to facilitate learning and assist in the planning and implementation phases of a project. This book includes approximately 30% new material, including chapters on the more recent technologies of RNA interference including: RNAi; Microarrays; Bioinformatics. It also includes new sections on: new and improved RT-PCR techniques; innovative 5’ and 3’ RACE techniques; subtractive PCR methods; methods for improving cDNA synthesis.
	Z700207	RNA Motifs and Regulatory Elements, 2nd ed.	This edition alerts the reader to the importance of regulatory RNA elements for the different areas of cellular life. The computational and experimental methods and tools to search for new interesting regulatory RNA structures are explained and compared. The knowledge on regulatory RNA structures and elements already available is concisely summarized. In addition, interesting RNA elements are analyzed in detail regarding their dynamics, regulation, and as a dominant topic of current research in molecular biology, including areas such as RNA mediated regulation of gene-expression, DNA/RNA chip data, and ribozymes, splicing, or telomerases in aging.
	Z704156	RNA Silencing: Methods and Protocols	A collection of readily reproducible methods for the design, preparation, and use of RNAs for silencing gene expression in cells and organisms. The techniques range widely and include methods addressing the biochemical aspects of the silencing machinery, RNA silencing in non-mammalian organisms, and the in vivo delivery of siRNAs and silencing vectors. There are also techniques for designing, preparing, and using RNAs to silence gene expression, for fine-tuning regulation by targeting specific isoforms of a given gene, and for the study and use of microRNAs. Protocols follow the Methods in Molecular Biology series format.
	Z701130	RNAi: A Guide to Gene Silencing Hardcover	The use of double-stranded RNA to silence gene activity has become widely and rapidly adopted. RNA interference is highly specific, remarkably potent, and acts on cells and tissues far removed from the site of introduction. The principles behind RNAi are just being uncovered, but this laboratory technique has been applied effectively in a wide variety of animal and plant species. Variations on RNAi are revolutionizing many approaches to experimental biology, complementing traditional genetic technologies with a quicker and cheaper way of mimicking the effects of mutations in both cell cultures and in living animals. This book presents the principles of RNA interference and reliable protocols for its laboratory use in C. elegans, Drosophila, plants, avian embryos, mammalian cells, mouse oocytes, and more.
	R5277	RT-PCR Protocols	A panel of molecular biologists and clinical researchers describe their novel, useful, and interesting RT-PCR applications. One will find reproducible protocols for highly sensitive detection and quantification of gene expression, the in situ localization of gene expression in tissue, and the cloning of genes, as well as for analyzing T-cell clones and the differential expression of genes. For someone seeking to extend the usefulness of RT-PCR, there are user-friendly applications that complement the latest technological advances, including laser-capture microdissection (LCM), real-time and quantitative PCR, microarray technology, cDNA cloning, and antibody engineering
	R7148	Radical-Mediated Protein Oxidation from Chemistry to Medicine	This unique and comprehensive volume brings together up-to-date information on the oxidation of amino acids, peptides, and proteins by free radicals and discusses the roles of such processes in biological systems. It pulls together aspects of protein oxidation from diverse fields: medicine, chemistry, biochemistry and contains an extensive bibliography drawing together thousands of references.
	Z405418	Radicals, Ion Radicals, and Triplets: The Spin-Bearing Intermediates of Organic Chemistry	This overview of all major types of spin-bearing radicals was written by an internationally acknowledged expert in the field with over two decades' research experience with radicals--important intermediates in organic reactions. While many new synthetic methods involving radicals have been developed and discussed in the past five years, this is the only book focusing on the physical-organic aspects of radical chemistry.
	Z235768	Radioactive And Stable Isotope Tracers In Biomedicine: Principles and Practice of Kinetic Analysis	A detailed, authoritative overview regarding all aspects of the theory and practice involved in utilizing isotopic tracers for the in vivo study of human metabolic function. Presents specific technical information on performing tracer studies including isotope infusion, analysis and interpretation of data.
	Z700975	Radioisotopes in Biology 2nd ed., A Practical Approach	This new edition is completely updated and a reference source for using radioactivity in the bioscience laboratory. It starts with three chapters that provide the reader with a thorough understanding of the issues to be considered in choosing a radioisotope and in its safe use. The key techniques of autoradiography and scintillation counting for the detection and quantitation of radioactivity are then covered in full practical detail. Four other chapters describe methods and approaches for the radiolabelling of nucleic acids and proteins, subcellular localization and identification of macromolecules, immunoassay and pharmacological techniques. Summaries of the legislative requirements for using radioisotopes in the USA and European Union are included.
	Z246166	Reaction Polymers: Polyurethanes, Epoxies, Unsaturated Polyesters, Phenolics, Special Monomers, and Additives Chemistry, Technology, Applications, Markets	The authors present a comprehensive review of the technical developments, research and markets for the major classes of reaction polymers. This book is of value to producers of reaction polymer raw materials, application molders and fabricators, and polymer researchers in industry and education.
	Z704598	Reagent Chemicals: Specifications and Procedures, 10th ed.	American Chemical Society Committee on Analytical Reagents is the only organization in the world that sets requirements and develops validated methods for determining the purity of analytical reagents. For the first time, Reagent Chemicals, 10th Edition includes general physical properties and analytical uses for all reagent chemicals, nearly 500 chemicals. Thirty-two new reagents and three new classes of standard grade reference materials are introduced in this edition. In addition, the use of Inductively Coupled Plasma Mass Spectrometry (ICP-MS), which is recognized as the most powerful and flexible trace element technique, is now accepted as an analytical method in the 10th edition. Other improvements include a CAS number index, a separate index for standard grade reference materials, frequently used mathematical equations, and complete assay calculations with titer values.
	Z730319	Real-Time PCR	With a variety of detection chemistries, an increasing number of platforms, multiple choices for analytical methods and the jargon emerging along with these developments, real-time PCR is facing the risk of becoming an intimidating method, especially for beginners. Real-time PCR provides the basics, explains how they are exploited to run a real-time PCR assay, how the assays are run and where these assays are informative in real life. It addresses the most practical aspects of the techniques with the emphasis on 'how to do it in the laboratory'.
	Z702447	Real-Time PCR: An Essential Guide	Real-time PCR (RT-PCR) is a powerful and rapid technique for nucleic acid amplification. The accumulation of specific products in a reaction is monitored continuously during cycling. This is usually achieved by monitoring changes in fluorescence within the PCR tube. This manual presents a comprehensive guide to the most appropriate and up-to-date technologies and applications. Topics covered include: Real-time PCR instruments and probe chemistries, set-up, controls and validation, quantitative real-time PCR, analysis of mRNA expression, mutation detection, NASBA, application in clinical microbiology and diagnosis of infection
	Z704369	Receptor Binding Techniques, 2nd ed.	A collection of methods for studying receptors in silico, in vitro, and in vivo. These techniques cover mining from curated databases, identifying novel receptors by high throughput screening, molecular methods to identify mRNA encoding receptors, radioligand binding assays and their analysis, quantitative autoradiography, and imaging receptors by positron emission tomography (PET). Highlights include phenotypic characterization of receptors in knockout mice, imaging receptors using green fluorescent protein and fluorescent resonance energy transfer, and quantitative analysis of receptor mRNA by TaqMan PCR. This book equips the researcher with techniques for exploring the unprecedented number of new receptor systems now emerging
	Z379816	Receptor Localization: Laboratory Methods and Procedures	A user-friendly guide to the latest techniques for localizing neurotransmitter receptors, in both the central and peripheral systems. It covers generalized procedures like genes and ligands and in vitro receptors. Additional focus is given to specialized applications like receptor sub-types. Standard laboratory methods and “tricks of the trade” are discussed by leading experts, and are fully illustrated.
	Z702536	Receptor Signal Transduction Protocols, 2nd ed.	This edition contains new key methodologies that have emerged recently for studying G protein-coupled receptors (GPCRs). The methods are focused primarily on events at the receptor level, including ligand binding, the genetic manipulation of receptors, the generation of model cell lines in which to study them, and the interaction and activation of G-proteins. Additional methods concentrate on receptor expression and localization, receptor internalization and post-translational modification, GPCR protein interactions, and the use of knock-out and knock-in strategies for determining the physiological roles of receptors.
	Z700983	Receptors: Structure and Function 2nd ed., A Practical Approach	Given the number of exciting developments across the spectrum of receptor research in recent years, the editors have not restricted themselves to one particular approach or class of receptors. Thus they include studies from G protein-coupled surface receptors to the delivery of antisense DNA inside living cells systems. This is a review of new methods for studying cellular receptors and examines how each technique can be used on different receptor types.
	Z702110	Recognition of Carbohydrates in Biological Systems, Part A: General Procedures, MIE Vol. 362	Recognition of carbohydrates in biological systems has been gaining more and more attention in recent years. Although methodology for studying recognition has been developing, there is no volume that covers the wide area of methodology of carbohydrate recognition. This volume and its companion, Volume 363, present state-of-the-art methodologies, as well as the most recent biological observations in this area. It covers the isolation/synthesis of substances used in studying interactions involving carbohydrates and discusses the methodology for measuring such interactions. Biological roles for such interactions are also covered.
	Z702129	Recognition of Carbohydrates in Biological Systems, Part B: Specific Applications, MIE Vol, 363	Recognition of carbohydrates in biological systems has been gaining more and more attention in recent years. Although methodology for studying recognition has been developing, there is no volume that covers the wide area of methodology of carbohydrate recognition. This volume and its companion, Volume 362, present state-of-the-art methodologies, as well as the most recent biological observations in this area. It covers carbohydrate-binding proteins and discusses glycoproteins and glycolipids. Polysaccharides, enzymes and cells are also covered
	R9261	Recombinant DNA, 2nd Edition	The application of recombinant DNA techniques to biology is bringing about a revolution in our understanding of living organisms. The aim of this edition is to show how recombinant DNA techniques have led to the explosion in our knowledge of fundamental processes.
	Z702854	Recombinant Gene Expression:Reviews and Protocols, 2nd ed.	In this edition, the editors have added critical reviews to a collection of protocols for gene expression in bacteria, fungi, plants, plant cells, animals, and animal cells. The review articles survey new directions in recombinant gene expression research, technique, and application, and point the way to using recombinant gene expression for metabolic engineering and the production of non-protein molecules. The protocols offer new host-vector systems, such as Anarctic bacteria and moderately halophytic bacteria, vectors for chromosomal editing and metabolic engineering, and information to aid in problem solving, strategy planning, and the promotion of protein folding.
	Z375586	Recombinant Protein Protocols: Methods in Molecular Biology, Vol. 63	Offers beginning and experienced researchers a firm foundation in the detection and isolation of a specific gene's recombinant protein. Practical and detailed information indispensable to successful large-scale production of defined gene products.
	Z379980	Recombinant Proteins from Plants: Production and Isolation of Clinically Useful Compounds	A comprehensive and detailed handbook of essential techniques for producing recombinant proteins in plant hosts. Focuses on large-scale, cost-effective production, but includes sufficient detail to permit methods development in single-cell expression systems. The authoritative panel of contributors also discuss techniques they believe will become more important in the future: efficient transformation with Agrobacterium, optimizing stability of plant-expressed proteins, and the immunotherapeutic potential of such proteins.
	R2267	Resin Microscopy And On-Section ImmunoCytoChemistry	This manual describes how fixation, resin embedding and immunocytochemistry are interrelated. This book enables non-microscopists to gain a quick grasp of basic principles.
	Z705632	Reverse Transcriptase Inhibitors in HIV/AIDS Therapy	This is a survey of all aspects of the reverse transcriptase inhibitors (RTIs) used to treat HIV/AIDS, including drug discovery, pharmacology, development of drug resistance, toxicity, and prevention of mother-to-child transmission of HIV/AIDS. The authors synthesize our current understanding of the role of reverse transcriptase in the viral life cycle, describe the discovery and development of eight nucleoside and nucleotide analogs that represent milestones in treatment history, and thoroughly discuss the question of toxicity and resistance to this class of drugs. They also address three non-nucleoside RTIs and their pharmacokinetics and comparative clinical efficacy, new RTIs currently under development, and the impact of approved agents on treatment, in general, and on vertical transmission in the developing world.
	Z375667	Ribozyme Protocols	A comprehensive collection of essential and easily reproducible techniques currently used by leading researchers to manipulate RNA and to inactivate gene expression in vivo. An indispensable volume not only for workers new to the field, but also for experienced researchers who want to expand their area of expertise. Some of the topics covered: • Synthesis of ribozymes in vitro and their application in vivo • Ribozyme design rules and production by transcription • Clinical potential of ribozymes • Computer programs that predict target Rna folding and help select ribozyme cleavage sites
	Z702331	Ribozymes and siRNA Protocols, 2nd ed.	In this edition, hands-on experts take advantage of the latest advances in ribozyme, DNAzyme, and RNA interference technologies to describe in detail the successful methods available for gene inactivation in vitro and in vivo. Their optimized techniques employ hairpin ribozymes, DNAzymes, hammerhead ribozymes and derivatives, group I intron ribozymes, Rnase P ribozymes, and siRNAs, as well as general methods for RNA structure analysis, delivery of oligonucleotides, and gene therapy. Also provided are novel methods for identifying accessible cellular mRNA sites; group I intron and RNAse P ribozymes protocols for effective design, selection, and therapeutic applications; and the latest RNAi methods for sequencing-specific gene silencing in a wide variety of organisms.
	Z705861	Roitt's Essential Immunology 11th ed.	Roitt's Essential Immunology has established itself as the book of choice for students of immunology worldwide. This excellent textbook is commonly regarded as 'the best of the immunology primers' and the eleventh edition remains at the cutting edge of this fascinating area of science. The trademark of this book is its highly readable introduction to the subject, its emphasis on core knowledge and its excellent four-color artwork. The internationally renowned authors have extensively updated all aspects of the book to produce a new edition, which will be an invaluable resource to students of immunology and medicine. Roitt's Essential Immunology is supported by a website at <www.roitt.com> This useful on-line resource includes interactive multiple-choice questions with feedback, key concepts explained with animations, further reading lists with PubMed links, and an archive of images from the book.
	R3401	Role of Catechol Quinone Species in Cellular Toxicity	This book provides in-depth description and analysis of the potential of catecholamine-quinones to destroy nerves in which they are synthesized, mechanisms by which this occurs, sites at which intervention is possible, and role of astroglia. Insight is gleaned from mechanisms of action of several neurotoxins, while analysis of mechanisms of chemically-related tetrahydroisoquinolines provides recognition of the neurotoxic potential of endogenously formed orthoquinones from catecholamines. This book is of value to those investigating catecholamine mechanisms of action, neurotoxins, Parkinson's Disease and other neurodegenerative disorders, carcinogenicity, particularly melanoma, and other cancers like leukemia.
	Z704539	The Ribosome: Protein Manufacturer, An Introduction	This book offers an economically sound resource for those who are interested in ribosomes and translation. It is the first book that integrates the synthetic life work, structural findings, regulation and evolution of ribosomes written from a single voice perspective. The history of ribosomal research and the known translational exceptions of the Genetic Code are included. Moreover, this lecture makes a concerted effort at incorporating newer structural information, so that it actually leads to a further and better understanding of biological translation.

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