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Chromatography books
Best Books for the Best Minds
Our Chromatography books offers a variety of titles on HPLC, GC, TLC and Affinity chromatography
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Book Title
Description
23499
AFFINITY CHROMATOGRAPHY PRINCIPLES/METHODS
A9595
Affinity Chromatography: Methods and Protocols
The methods detailed range from immunoaffinity chromatography to state-of-the-art phage-display technology in the discovery of affinity ligands and drugs. Included are reproducible separations of such small molecules as haptens, protein ligands, and supramolecular structures. Each chapter is devoted to a specific technique and includes step-by-step instructions. Practical notes suggest alternative procedures and describe how to overcome problems that may occur.
Z378127
Affinity Separations: A Practical Approach
This small, accessible volume covers a remarkable range of techniques for affinity-based purification. Separate chapters are devoted to purification of proteins, nucleic acids, and oligosaccharides. Immunoaffinity applications and the use of affinity tags for recovering recombinant proteins are also thoroughly covered. Even affinity-based cell sorting receives a chapter. This is a practical reference for everyday use.
A5847
Affinity and Immunoaffinity Purification Techniques
Application of affinity and immunoaffinity ligands is an essential aid in the selective isolation of specific analytes. Techniques have nuances, such as ligand orientation, ligand stability, and bound analyte recovery, that can hinder successful isolation of the desired material and result in suboptimal or nonrecovery. Other reasons for failure are that separation science approaches an art form, and that tricks essential for success are lost in the text or missing from published articles. This is a sound guide for those wishing to use these techniques in their experimental designs.
Z507814
Applied Thin-Layer Chromatography: Best Practice and Avoidance of Mistakes
Thin layer chromatography (TLC) is a powerful, fast and inexpensive analytical method. It has proven its usefulness in pharmaceutical, food and environmental analysis. This book explains how to best utilize this technique and avoid costly, time-wasting mistakes.
500003
Basic Gas Chromatography
This book is a product of three basic gas chromatographic courses that Varian Aerograph offers throughout the world. Useful data are presented, including calibration factors for detectors, chemical structures of liquid phases, and methods for preparing liquid phases and packing columns. The authors hope readers will confirm their belief that a major advantage of GC is its simplicity.
Z406406
Basic Gas Chromatography: Techniques in Analytical Chemistry
From Book News, Inc.
Offers thorough coverage of basic principles and techniques of modern gas chromotography, serving as a primer/working reference for bench chemists and as a text for upper-level undergraduate and graduate students. Theoretical issues are explained without complicated equations and derivations and always in terms of how they relate to practical operating principles. Coverage includes both capillary column and packed column chromotography, as well as cutting-edge topics such as chiral analysis and solid phase microextraction. Includes step-by-step guidelines and trouble shooting tips, reference appendices, and use of new IUPAC terms cross-referenced to traditional terms and symbols.
Book News, Inc.
®
, Portland, OR
B4681
Bioseparations Engineering: Principles, Practice and Economics
Opportunities are growing to apply separation science to the production of therapeutic compounds, specialty biochemicals, functional food ingredients, environmentally friendly biocatalysts and new bioproducts from renewable sources. This book covers methods, theory and materials that reduce the science of bioseparations to practice in the lab or plant. Examples address purification of biomolecules ranging from recombinant proteins to gene therapy products, with footnotes detailing economics of the products. Topics cover isocratic and gradient chromatography; sedimentation, centrifugation and filtration; membrane system; and precipitation and crystallization.
Z515027
Century of Separation Science
This impressive reference presents an extensive overview of the critical developments in separation science since 1900—covering the most recent advances in chromatography, electrophoresis, field-flow fractionation, countercurrent chromatography, and supercritical fluid chromatography for high-speed and high-throughput analysis. It contains a list of recommended reading for complete coverage of the fundamentals, principles, methods, and procedures of separation science. It discusses topics such as a) current techniques in solid phase extraction, microfluidics, capillary and slab gel electrophoresis, and gas, ion, affinity, and thin-layer chromatography, b) the emergence of microchip electrophoresis for multisample analysis, c) modern detection and purification processes for new biomedical compounds, d) the evolution of capillary column gas chromatography, e) contemporary analytical tools for biological, environmental, and industrial applications.
Z285862
Chromatographic Analysis of Pharmaceuticals, 2nd ed.
A new edition of the reference guide exploring the chromatographic methods used for the measurement of drugs, impurities, and excipients in pharmaceutical preparations such as tablets, ointments, and injectables. Seven chapters deal with specific chromatography topics related to regulations, sample pretreatment, gas, high-performance liquid, capillary electrophoresis, and supercritical fluid. The volume also features a 148 page applications table listing the chromatographic data of over 1300 drugs and related substances. Includes tables and graphs
Z515019
Chromatography Theory
This reference presents a comprehensive overview of the principles, methods, and fundamental theories used in chromatographic separations—identifying recent advances, mathematical relationships, and useful design techniques for optimal system operation and control of chromatographic variables.
Discussing thermodynamic and dynamic mechanisms and key terminology clearly and concisely, Chromatography Theory explains
• the principles of flow, temperature, and solvent programming
• the mechanisms of retention
• factors that control peak dispersion
• the impact of dispersion control on instrument design and construction
• performance criteria for accurate chromatographic analyses
• efficient applications of column design
• the effect of mass overload on separation processes
• relevant dynamics in thin layer chromatography
Supplemented with more than 300 equations, Chromatography Theory is an authoritative and essential source for chromatographers and mass spectroscopists; analytical chemists; chemical engineers; lab technicians and researchers; environmental and biopharmaceutical chemists, biochemists, and biotechnologists, and upper-level undergraduate and graduate students in these disciplines.
Z702064
Chromatography and Separation Science
The basic objectives of this book are to: provide basic information on chromatography and separation science; show how simple extraction and partition processes provide the basis for development of chromatography and separation science; describe the role of chromatography and separation science in various fields; discuss the role of chromatography and separation science in development of new methodology; and present new evolving methods and how to select an optimum method.
D4816
DNA Chromatography
This book describes DNA Chromatography a powerful and effective tool for the molecular biologist researcher. The technology is useful for a variety of applications including the analysis of mutations (SNPs, insertions, and deletions), the size determination of PCR products, the purification of single- and double-stranded nucleic acids, analysis of enzymatic reaction products and many others. DNA Chromatography is automated and can replace many of the gel electrophoresis technologies being used resulting in faster and more accurate analysis.
Z286788
Encyclopedia of Separation Technology
Separations technologies on an industrial scale comprise over 50 percent of the capital and operating costs in industry. This two-volume encyclopedia, based on the authoritative Kirk-Othmer Encyclopedia of Chemical Technology, provides A to Z coverage of the various techniques that can be used to effect separations of gases, liquids, and solids for the purification of new materials, feedstocks, process streams, or finished products. Written by experts in the field, entries provide valuable information on both the technology and the underlying science of separations. This book brings together all of the authoritative articles on separation technology from the main Kirk-Othmer Encyclopedia into a thoroughly updated, easily accessible two-volume set; Contains over 30 percent new and updated material; Includes five new specially commissioned articles on key topics - such as bioseparations, contactors for separations processes, and high purity gases
Z540617
Essential Oils Analysis by Capillary Gas Chromatography and Carbon-13 NMR Spectroscopy, 2nd Edition
In addition to capillary gas chromatography and GC-MS, carbon-13 NMR spectroscopy provides an alternative method for essential oils analysis. The excellent visual spacing of the signals enables oil samples to be analyzed without preliminary separation of their components. Also, information relating to the molecular structure of the oil constituents can be ascertained from the measured chemical shifts. This edition clearly demonstrates the power of the technique in the characterization of essential oils, based on 60 sample oils chosen for their industrial importance together with the 188 carbon-13 NMR spectra of significant components. Supporting data are presented using capillary gas chromatography.
Z705918
Forensic and Clinical Applications of Solid Phase Extraction
This complete laboratory reference manual explains the principles behind solid phase extraction (SPE) and provides readily reproducible protocols for solving extraction problems in forensic and clinical chemistry. Numerous actual chromatograms, based on original research and diverse applications, demonstrate the technique and the results that can be achieved. Extensive appendices allow fast access to frequently needed information on reagents, the preparation of solutions and buffers, milliequivalent and millimode calculations, buffers and pKa for SPE, and a complete RapidTrace® technical manual. Each protocol is described in step-by-step detail and contains tips on troubleshooting and on avoiding known pitfalls.
Z271756
Gas Chromatography, 2nd ed.
This book presents an introduction to gas chromatography, including examples of applications. Shows readers malfunctions that can occur enabling them to recognize and fix faults.
Z402338
HPLC Columns: Theory, Technology, and Practice
High performance liquid chromatography (HPLC) is the most common analytical method for separating substances into their individual components. As the separations occur in a column, this part of the HPLC apparatus is crucial to achieving the best results. This state-of-the-art overview of HPLC column technology covers fundamental principles, column selection criteria and special techniques.
Z730149
HPLC Made to Measure: A Practical Handbook for Optimization
The only topical HPLC book to focus on optimization, this volume addresses the needs of HPLC users who wish to constantly improve their methods, in particular in terms of throughput, accuracy and cost-effectiveness. This handbook features contributions from such bestselling authors as John W. Dolan, Michael McBrien, Veronika R. Meyer, Uwe D. Neue, Lloyd R. Snyder, and Klaus K. Unger, as well as from scientists working for major companies, including Agilent, AstraZeneca, Merck, Schering, Tosoh Biosep, VWR, and Waters. It covers essential aspects of optimization in general, optimization in different LC-modi, hyphenated techniques and computer-aided optimization. The whole is rounded off with a section of user reports.
Z424382
HPLC Methods for Pharmaceutical Analysis 4-Volume Set
Provides fast, hands-on access to thousands of abstracts from the current literature on HPLC methods for pharmaceutical analysis.
The most commonly used method for analyzing substances, and the first method most researchers turn to, is high performance liquid chromatography (HPLC). Following up on a best-seller, volumes 1-4 continue to provide an easily-accessible collection of procedures for analyzing pharmaceuticals using HPLC.
Z704296
HPLC Methods for Recently Approved Pharmaceuticals
Stop wasting time hunting for the right HPLC assay techniques. With this book, you will quickly identify and replicate the ideal procedures without having to refer to original source publications. It arms you with established HPLC assay techniques for hundreds of newly approved drugs, as well as drugs for which assay methods were only recently developed. This handbook includes: HPLC methods for 390 commonly prescribed pharmaceutical compounds; Methods for drugs in biological fluids and for bulk and formulated drugs; Chemical structures, molecular weights and formulas, and CAS Registry Numbers; Cross-references to The Merck Index; Retention times of other drugs that can be assayed using the same methods.
Z514233
HPLC Solvent Guide, 2nd Ed.
Solvent selection is perhaps the most commonly overlooked parameter in HPLC. Even the most experienced analytical chemist tends to select one of three familiar solvents. The HPLC Solvent Guide provides detailed coverage of all commonly used HPLC solvents used in a wide range of separations. This book give a practical overview of the role of solvents in HPLC method development. Details the physical, chemical, and chromatographic properties of the solvents followed with specific analytes.
Z730246
HPLC for Pharmaceutical Scientists
HPLC for Pharmaceutical Scientists
is an excellent book for pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.
Z702269
HPLC of Biological Macromolecules, 2nd ed.
Revised and expanded to reflect recent innovations in HPLC, this authoritative reference presents practical strategies for the evaluation and analysis of proteins, peptides, and polynucleotides and offers class-specific applications for the characterization and fractionation of biological macromolecules. With contributions from experts, this edition provides new chapters summarizing specialized detection systems; current discussions on the chemical and biological properties of specific biomolecules; detailed guidelines for the development of modern analytical techniques; state-of-the-art exploration methods for complex mixtures; successful implementation and investigation procedures.
H3409
HPLC of Macromolecules
High pressure (or performance) liquid chromatography is a standard biochemical technique used for the separation of molecules. This volume covers the larger biomolecules - oligosaccharides, glycopeptides, oligonucleotides, polypeptides, and proteins. It also includes the latest advances in microbore and packed capillary technology and the use of mass spectrometric detection.
Z701890
HPLC of Peptides and Proteins: Methods and Protocols
Hands-on experts from academia and industry describe how to successfully perform all the critical HPLC techniques needed for the analysis of peptides and proteins. The methods range from commonly used techniques to those for capillary to large-scale preparative isolation. The authors have also presented a number of specific applications as case studies to illustrate the analytical approaches to a particular separation or assay challenge, with examples drawn from contemporary fields in biochemistry and biotechnology
Z525391
HPLC: Practical and Industry Applications, 2nd ed.
Since the publication of the first edition, the areas of mass spectroscopy, electrophoretic separations, and ultra-micro separations have blossomed. The Second Edition addresses all of these changes and more. The book is fully current, examining analytical HPLC as it is actually used in industry.
23582
HYDROPHOBIC INTERACTION CHROMATOGRAPHY PRINCIPLES/METHODS
Z424234
Handbook of Derivatization Reactions for HPLC, Book and CD-ROM
This print and electronic database represents a tremendous time-saver for analytical chemists working in the popular area of HPLC. By abstracting and evaluating the most important derivatization procedures, chemists can avoid lengthy information searches to consult the primary literature. Both the print and fully-searchable CD-ROM databases offer everything an analytical chemist needs to conduct derivatizations.
Z703443
Handbook of Ion Chromatography, 3rd Completely revised edition
The third edition of this highly successful handbook has been completely revised and considerably extended, making it unrivaled in the timeliness and comprehensiveness of the information presented. This new edition runs to two volumes, with added chapters or sections that cover new and important applications of ion chromatography in the life sciences, such as the analysis of proteins, nucleic acids, amino acids or carbohydrates. Also, new instrumentation that meets the demand for miniaturization and reduced analysis times; Coupling of ion chromatography to mass-spectrometric or inductively coupled plasma detectors; and Validation of ion-chromatographic methods, which is important for quality assurance.
Z550957
Handbook of Thin-Layer Chromatography, 3rd edition
Written by over 40 internationally acclaimed authorities on thin-layer chromatography (TLC), this comprehensive Second Edition presents the latest techniques, instrumentation, and applications of overpressurized, rotational, and high-performance quantitative TLC.
Z369551
High Performance Liquid Chromatography: Principles and Methods in Biotechnology
Theoretical and practical aspects of the application of HPLC to the biosciences are presented. This includes sample preparation, column selection, detection, preparative HPLC, and the use of HPLC for specific biomolecules. Comparisons between HPLC and alternative bioseparation methods are also discussed.
Z424609
Ion Chromatography, 3rd Edition
Describes materials, principles, and methods of ion chromatography in a clear and concise style. It is filled with handy tables such as detection and elution conditions. With this new edition, the scope has been enlarged to include capillary electrophoresis as well as chemical speciation.
Z705594
LC/MS - A Practical User's Guide
This book is a hands-on reference that focuses on the practical applications and techniques needed to use LC/MS successfully. The author presents empirical methods for optimizing the techniques, maintaining the instrumentation, and choosing the appropriate MS or LC/MS analyzer. It covers everything users need to know about the latest equipment, including quadrupole, time-of-flight, and ion trap analyzers; cutting-edge processes, such as preparing HPLC mobile phases and samples; handling and maintaining a wide variety of silica, zirconium, and polymeric separation columns; interpreting and quantifying mass spectral data; and using MS interfaces; current and future applications in the pharmaceutical and agrochemical industries, biotechnology, clinical research, environmental studies, and forensics An accompanying PowerPoint® slide-set on CD-ROM provides vital teaching tools for instructors and new equipment operators.
Z514829
LC/MS Applications in Drug Development
The premier reference on the cutting-edge technology driving new drug development
Breakthroughs in combinatorial chemistry and molecular biology, as well as an overall industry trend toward accelerated development, mean the rate of sample generation now far exceeds the rate of sample analysis in the pursuit of producing new and better pharmaceuticals. LC/MS is an analytical tool that helps the researcher identify the most promising sample early in the selection process, effectively creating a shortcut to finding new drugs. This book is the first to describe LC/MS applications within the context of drug development, including the discovery, preclinical, clinical, and manufacturing phases.
In addition to the thorough technical analysis of this tool, LC/MS Applications in Drug Development provides perspective on the significant changes in strategies for pharmaceutical analysis. A process overview of drug development from an analytical point of view is provided along with essential data required to successfully bring a drug to market. The incorporation of LC/MS is illustrated from target to product. Chapters pertaining to the discovery process itself include:
• Proteomics
• Glycoprotein Mapping
• Natural Products Dereplication
• Lead Identification Screening
• Open-Access LC/MS
• In Vivo Drug Screening
• In Vitro Drug Screening
Written for both the analytical chemist who uses LC/MS applications and the pharmaceutical scientist who works with the drugs they produce, LC/MS Applications in Drug Development is the premier reference on the subject.
Z702080
Liquid Chromatography - Mass Spectrometry: an introduction
With the advent of new interfacing technology, the benefits of LC-MS (liquid chromatography with mass spectrometry), are being realized by the growth in applications of this technique in both the chemical and life sciences. Topics covered include: Limitations of the component techniques when used in isolation, and how a combination of the two allows these to be overcome; Descriptions of the various approaches, including thermospray, electrospray and atmospheric pressure chemical ionization, which are used to interface the two techniques, along with the advantages and disadvantages of each system; Illustrative examples of the applications of LC-MS, including the molecular weight and structure determinations of both biopolymers and low-molecular-compounds.
Z702293
Methods for Affinity-Based Separations of Enzymes and Proteins
One major concern of biotechnology is either using enzymes or producing them. Enzyme/protein production is therefore an important starting point for biotechnology. Bioseparation or downstream processing constitutes about 40-90% of the total production cost. Driven by economics, highly selective technologies applicable to large-scale processing have emerged. These technologies are slowly diffusing to enzymologists who are working on a smaller scale, looking for fast and efficient purification protocols. The affinity-based techniques (including precipitation, two-phase extractions, expanded bed chromatography, perfusion chromatography and monoliths) described in this volume provide current and cutting-edge methods.
Z705675
Modern HPLC for Practicing Scientists
Written by a practitioner, this book is a concise text which presents the most important High-Performance Liquid Chromatography (HPLC) fundamentals, applications, and developments. It describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. Moreover, the book serves well as an updated reference guide for busy laboratory analysts and researchers. Topics covered include HPLC operation, Method development, Maintenance and troubleshooting, Modern trends in HPLC such as quick-turnaround and "greener" methods, and Regulatory aspects. While broad in scope, this book focuses particularly on reversed-phase HPLC, the most common separation mode, and on applications for the pharmaceutical industry, the largest user segment.
Z558443
Modern Practice of Gas Chromatography, 4th edition
Imcorporates the most recent developments in the field, including gas chromatography/mass spectrometry (GC-MS), optimization of separations and computer assistance, high speed or fast gas chromatography, mobile phase requirements, qualitative and quantitative analysis by GC, validation and QA/QC of chromatographic methods, and useful hints for good gas chromatography.
Z703540
More Practical Problem Solving in HPLC
A unique approach to solving HPLC problems. Everyone who bought "Problem Solving in HPLC" by Kromidas will equally benefit from nearly 100 new practical examples for optimization, trouble-shooting, and instrument performance given