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Description
Biochem/physiol Actions
Product #
Acetyl-Ser-Asp-Lys-Pro ≥97% (HPLC)
Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice. It is a specific substrate for the N-terminal active site of angiotensin converting enzyme, which is responsible for its degradation
in vivo
.
A6433
[Val
5
]-Angiotensin I bovine ≥97% (HPLC)
Angiotensin I is a putative neurotransmitter. It is the precursor of angiotensin II and of angiotensin fragment 1-7, which are the hormones involved in regulation of fluid volume and the release of aldosterone.
A9402
Angiotensin Fragment 1-7 acetate salt hydrate ≥90% (HPLC), powder
Angiotensin I metabolite that is an AT
2
receptor agonist.
A9202
Angiotensin I human acetate salt hydrate ≥90% (HPLC)
Angiotensin I is a putative neurotransmitter. It is the precursor of angiotensin II and of angiotensin fragment 1-7, which are the hormones involved in regulation of fluid volume and the release of aldosterone.
A9650
Ala-Pro-Gly-[Ile
3
, Val
5
]-Angiotensin II acetate salt hydrate ≥97% (HPLC)
A0289
[Asn
1
, Val
5
]-Angiotensin II ≥97% (HPLC)
Angiotensin agonist that has been isolated from kallikrein or renal-extract treated plasma and is involved in the regulation of blood pressure, water consumption, and hydromineral balance in fish.
A6402
[Sar
1
, Gly
8
]-Angiotensin II acetate salt hydrate ≥97% (HPLC)
Angiotensin II antagonist
A7401
[Sar
1
, Leu
8
]-Angiotensin II acetate salt hydrate ≥97% (HPLC)
Angiotensin II antagonist
A8276
[Sar
1
, Thr
8
]-Angiotensin II acetate salt hydrate ≥97% (HPLC)
Potent, long-acting antagonist of angiotensin II.
A9900
[Sar
1
, Val
5
, Ala
8
]-
Angiotensin II acetate salt hydrate ≥97% (HPLC), powder
Competitive angiotensin II antagonist; inhibits pressor effects of angiotensin II in rats and lowers blood pressure in humans.
A2275
[Val
5
]-Angiotensin II acetate salt hydrate ≥95% (HPLC), powder
Angiotensin II analog that is an agonist at
1
angiotensin receptors.
A2900
Angiotensin II human ~95% (HPLC), powder
Angiotensin (Ang) II is important in regulating cardiovascular hemodynamics and cardiovascular structure. Most of the known effects of Ang II in adult tissues are attributable to the angiotensin II type I (AT
1
) receptor. The AT
1
and AT
2
receptors have differential pharmacological and biochemical properties and appear to exert opposite effects in terms of cardiovascular hemodynamics and cell growth. In addition, the renin-angiotensin and nitric oxide-generating systems appear to interract in the regulation of cardiovascular function. Ang II stimulates angiogenesis and increases microvessel density. In nature, angiotensin II is produced by the action of angiotensin converting enzyme on angiotensinogen; the C-terminal-His-Leu is cleaved.
A9525
[des-Arg
1
]-
Angiotensin III ≥95% (HPLC), lyophilized powder
A1599
[Ile
7
]-Angiotensin III acetate salt hydrate ≥95% (HPLC)
A0911
[Sar
1
, Ile
7
]-Angiotensin III acetate salt hydrate ≥97% (HPLC)
Selective antagonist of angiotensin-III.
A4455
[Val
4
]-Angiotensin III acetate salt hydrate ≥97% (HPLC)
A6277
Angiotensinogen from human plasma ≥80% (SDS-PAGE), lyophilized powder
A2562
Angiotensinogen from porcine plasma lyophilized powder, 1,500-3,000 units/g protein
A2283
Angiotensinogen from porcine plasma
BioChemika
, ~65% protein basis, ~2 units/mg
10381
Angiotensinogen Fragment 11-14 ≥97% (HPLC)
A0417
Apelin-13 trifluoroacetate salt ≥95%
Synthetic endogenous peptide agonist for the human APJ receptor, a putative receptor protein related to the angiotensin receptor (AT
1
). This peptide exerted an acidification-rate-promoting activity in CHO cells expressing the APJ receptor with a median effective concentration (EC
50
) value of 0.37 nM. Blocks HIV-1 and HIV-2 entry into cells expressing the APJ receptor.
A6469
CGP-42112A ≥95%, synthetic, solid
Potent AT
2
angiotensin II receptor agonist.
C160
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