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Endothelins
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Agonists
Endothelin
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Description
Biochem/physiol Actions
Product #
BQ-3020 ≥90%, powder
Selective ET
B
endothelin receptor agonist.
E139
Endothelin 1
BioChemika
, ≥97.0% (HPLC)
Potent agonist for ET
A
and ET
B
endothelin receptors. Induces the production of hypoxia-inducible factor 1α, and, thus, the production of VEGF.
45187
Endothelin 1 ≥97% (HPLC), powder
Potent agonist for ET
A
and ET
B
endothelin receptors. Induces the production of hypoxia-inducible factor 1α, and, thus, the production of VEGF.
E7764
[Ala
1,3,11,15
]-
Endothelin 1
Selective agonist for ET
B
endothelin receptors.
E6877
Endothelin 2, human
BioChemika
, ≥97.0% (HPLC)
45188
Endothelin 2 human ≥97% (HPLC), powder
Potent vasoconstrictor from vascular endothelial cells; displays similar selectivity for ET
A
and ET
B
endothelin receptors
E9012
Endothelin 3 human, rat ≥97% (HPLC), powder
Potent vasoconstrictor from vascular endothelial cells; preferred agonist for ET
B
endothelin receptors. Induces the production of VEGF.
E9137
IRL-1620 powder
Selective ET
B
endothelin receptor agonist.
E137
Sarafotoxin S6a1 ≥97% (HPLC)
S1522
Sarafotoxin S6b
Atractaspis engaddensis
sequence ≥90% (HPLC)
ET
A
agonist; increases intracellular Ca
2+
S4146
Sarafotoxin S6c ≥97% (HPLC)
ET
B
agonist; toxin with strong vasoconstrictor activity
S6545
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