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MISSION shRNA-RNAi
MISSION siRNA
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Description
Biochem/physiol Actions
Product #
des-Ac-α-Melanocyte Stimulating Hormone ≥97% (HPLC)
Retains ~10% of the activity of α-MSH.
M8267
Diacetyl-α-Melanocyte Stimulating Hormone ≥97% (HPLC)
M7896
HS014 ≥95% (HPLC), lyophilized powder
Selective MC4 receptor antagonist that increases food intake in free-feeding rats.
H2396
[Met
210
]-
Melanocyte Protein PMEL 17 Fragment 209-217 human, mouse >98% (HPLC), solid
Modification of the melanoma differentiation antigen gp100/PMEL 17 fragment 209-217 sequence with greater affinity for the HLA-A2 molecule than the unmodified peptide. Has an increased ability to generate melanoma-reactive cytotoxic T lymphocytes
in vitro
.
M0563
α-Melanocyte stimulating hormone ≥97% (HPLC)
Hormone that stimulates melanogenesis; facilitates learning and memory; affects inflammatory and immune responses and peripheral nerve regeneration.
M4135
[Nle
4
,
D
-Phe
7
]-
α-Melanocyte Stimulating Hormone trifluoroacetate salt ≥95% (HPLC)
Analog is 26 times as potent as α-MSH in the adenylate cyclase assay.
M8764
γ-Melanocyte Stimulating Hormone ≥97% (HPLC)
Hormone that stimulates melanogenesis; facilitates learning and memory; affects inflammatory and immune responses and peripheral nerve regeneration.
M9638
[Deamino-Cys
3
, Nle
4
, Arg
5
, β-(2-Naphthyl)-
D
-Ala
7
, Cys
11
]-α-
Melanocyte Stimulating Hormone Amide Fragment 3-11 ≥97% (HPLC), solid
M0313
Acetyl-[Nle
4
, Asp
5
,
D
-2-Nal
7
, Lys
10
]-cyclo-
α-Melanocyte Stimulating Hormone Amide Fragment 4-10 ≥95% (HPLC)
Screening analogs of the cyclic lactam melanocortin agonist MTII led to the identification of the agoutimimetic SHU9119. This compound shares pharmacological properties with the agouti peptide in that it is a potent antagonist of the melanocortin-4 receptor and a less potent antagonist of the melanocortin-3 receptor.
M4603
[
D
-Trp
7
, Ala
8
,
D
-Phe
10
]-
α-Melanocyte Stimulating Hormone Amide Fragment 6-11 ≥97% (HPLC)
Selective inhibitor of α-MSH activity in frog skin bioassay; identical to (His
1
,Lys
8
)-GH which selectively releases growth hormone
in vitro
and
in vivo
; somatostatin antagonist.
M2910
N-Acetyl-[Cys
4,10
,
D
-Phe
7
]-
α-Melanocyte Stimulating Hormone Fragment 4-13 ≥95% (HPLC)
Cyclic MSH analog that is resistant to tryptic degradation; potent agonist with prolonged melanotropic activity in frog and lizard skin bioassays.
M7907
β-Melanocyte Stimulating Hormone human ≥95% (HPLC)
Hormone that stimulates melanogenesis; facilitates learning and memory; affects inflammatory and immune responses and peripheral nerve regeneration
M6513
β-Melanocyte Stimulating Hormone porcine ≥97% (HPLC)
Hormone that stimulates melanogenesis; facilitates learning and memory; affects inflammatory and immune responses and peripheral nerve regeneration
M2018
[Val-OH
13
]-α-
MSH ≥97% (HPLC)
M7892
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