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Other Amyloid Protein Fragments

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Description	Biochem/physiol Actions	Product #
DABCYL-[Asn⁶⁷⁰, Leu⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 fragment 661-675−EDANS trifluoroacetate salt ≥97% (HPLC), solid	β-secretase substrate.	A4972
Amyloid β/A4 Precursor Protein 770 Fragment 667-676 ≥96% (HPLC), solid	Wild-type amyloid precursor protein β-secretase cleavage site substrate.	A3222
[Asn⁶⁷⁰, Leu⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt ≥95% (HPLC), solid	Substrate for assaying β-secretase activity that corresponds to the "Swedish" Lys-Met/Asn-Leu mutation of the amyloid precursor protein β-secretase cleavage site.	A1972
Arg-Glu(EDANS)-[Asn⁶⁷⁰, Leu⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 Fragment 669-674-(DABCYL)Lys-Arg ≥96% (HPLC), solid		A2847
7-Methoxycoumarin-4-acetyl-[Asn⁶⁷⁰, Leu⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 Fragment 669-674-(2,4-dinitrophenyl)Lys trifluoroacetate salt ≥96% (HPLC)	β−Secretase substrate	A1597
DABCYL-[Asn⁶⁷⁰, Leu⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 Fragment 669-674-EDANS ammonium salt ≥95% (HPLC), solid	β-Secretase substrate.	A5097
Amyloid β/A4 Precursor Protein Fragment 328-332 98% (HPLC), lyophilized powder		A8844
Amyloid BRI Protein Precursor 227 Fragment 89-106 ≥81% (HPLC), solid	Peptide fragment found within the Amyloid BRI peptide.	A3347
Amyloid Precursor Protein α (304-612), Secreted human >90% (SDS-PAGE), recombinant, expressed in Escherichia coli (N-terminal histidine tagged), buffered aqueous solution	Secreted Amyloid Precursor Protein α (sAPPα) is a 612 amino acid protein produced from the ubiquitously expressed β-Amyloid precursor protein (βAPP), 695 isoform, by α-secretase cleavage. sAPPα (304-612) is a fragment of sAPPα designed to lack the N-terminal domain of the full length protein.	S8065
Amyloid Precursor Protein α (444-612), Secreted human >90% (SDS-PAGE), recombinant, expressed in Escherichia coli (N-terminal histidine tagged), buffered aqueous solution	Secreted amyloid precursor protein α (sAPPα) is a 612 amino acid protein produced from the ubiquitously expressed β-Amyloid precursor protein (βAPP), 695 isoform, by α-secretase cleavage. The sAPPα (444-612) fragment was designed to contain a sequence that is linked to the attenuation of glutamate exocitotoxicity and to the promotion of neurite outgrowth. In addition, it contains the C-terminal domain corresponding to sAPPα (597-612) that acts as a heparin-binding domain.	S8190
Amyloid Precursor Protein α, Secreted human >90% (SDS-PAGE), recombinant, expressed in Escherichia coli (N-terminal histidine-tagged), buffered aqueous solution	β-Amyloid precursor protein (βAPP) is ubiquitously expressed in many tissues and is conserved in evolution. Following proteolytic cleavage by β and γ secretase it provides a 4 kDa β peptide which forms extracellular fibrillar amyloid deposits, a defining feature of Alzheimer's disease.	S9564
Amyloid Precursor Protein N-Terminal Peptide lyophilized powder	Believed to play a role in beta-amyloid plaque formations resulting in the hastening of the onset and progression of Alzheimer's disease.	A1473
Amyloid Protein Non-Aβ Component ≥80% (HPLC)	Found in the insoluble core of amyloid plaque; forms fibrils via a nucleation-dependent polymerization mechanism	A2835
7-Methoxycoumarin-4-acetyl-[Asn⁶⁷⁰,Leu⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 (667-676)-(2,4-dinitrophenyl)Lys-Arg-Arg Amide ≥96% (HPLC)		A1347

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