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Thrombin
Inhibitors
Thrombin Technical Information
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Description
Biochem/physiol Actions
Product #
N-Acetyl-eglin C recombinant, expressed in proprietary host
Inhibitor of chymotrypsin, subtilisin, leukocyte elastase and cathepsin G.
E7888
Leupeptin trifluoroacetate salt ≥90% (HPLC), microbial
Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain and cathepsin B. No inhibition found with pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. Effective concentration 10-100 μM.
L2023
N
α
-
Tosyl-
L
-lysine chloromethyl ketone hydrochloride ≥96% (TLC), powder
Blocks the LPS- or cytokine-induced activation of nuclear factor κB (NFκB), which, in turn, blocks the induction of iNOS and COX-2 transcription. Blocks activation of pp70
s6k
by all mitogens. Blocks apoptosis in cell lines by inhibiting the processing of caspases in some cell lines and to some stimuli.
T7254
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