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Gangliosides

Description
Biochem/physiol Actions
CAS Number
Product #
Asialoganglioside GM1 from bovine brain ~98%, lyophilized powder Removing the sialic acid from monosialoganglioside GM1 inhibits its ability to bind cholera toxin. Asialoganglioside GM1 does not block the binding of cholera toxin to cellular GM1.
 71012-19-6 G3018
Asialoganglioside-GM2 from bovine brain ~95%, lyophilized powder Degraded form of Asialoganglioside-GM1 ganglioside.
 35960-33-9 G9398
Disialoganglioside GD1a from bovine brain ≥95% (TLC), lyophilized powder The major ganglioside in brain. Converted to GM1 by bacterial and mammalian sialidase. Differentiation marker for cell growth.
 12707-58-3 G2392
Disialoganglioside GD1b from bovine brain ~95%, lyophilized powder May act as a bacterial toxin receptor (tetanus, botulinus); high levels found in gliomas and astrocytomas.
 19553-76-5 G8146
Disialoganglioside-GD2 from bovine brain ~95%, lyophilized powder, semisynthetic Cell surface component from disialoganglioside-GD1b.
 65988-71-8 G0776
Lysoganglioside-GM1 from bovine brain ≥95%, lyophilized powder Suggested to be a modulator of cell growth and signal transduction. Accumulates in the nervous system of patients with GM1 gangliosidosis. Used for the preparation of GM1 derivatives containing different fatty acids, fluorescent tags, or other residues.
 171483-40-2 G5660
Monosialoganglioside GM1 from bovine brain ≥95%, lyophilized powder 37758-47-7 G7641
Monosialoganglioside GM1 from bovine brain lyophilized powder, γ-irradiated, ≥95% (TLC) 37758-47-7 G9652
Monosialoganglioside GM2 from bovine brain ≥95% (TLC) Minor component of cell membranes that has been shown to accumulate in Tay-Sachs disease.
 19600-01-2 G8397
Monosialoganglioside GM3 from canine blood ≥98%, lyophilized powder Monosialoganglioside-GM3 is the most common ganglioside and the major ganglioside in non-neuronal cell membranes. It inhibits epidermal cell growth and is involved in the biosynthesis and metabolism of all higher gangliosides.
 54827-14-4 G5642
Monosialoganglioside GM3 from canine blood lyophilized powder, γ-irradiated, cell culture tested Monosialoganglioside-GM3 is the most common ganglioside and the major ganglioside in non-neuronal cell membranes. It inhibits epidermal cell growth and is involved in the biosynthesis and metabolism of all higher gangliosides.
 54827-14-4 G0153
Trisialoganglioside-GT1b from bovine brain lyophilized powder, ≥96% (TLC) Ganglioside marker for metastatic brain tumors. Modulates cellular differentiation; prevents glutamate neurotoxicity; inhibits mitogenesis stimulated by lectins such as ConA. Converted to GD1b by bacterial and mammalian sialidases.
 59247-13-1 G3767

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