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Lectins and Lectin Antibodies

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Description	Biochem/physiol Actions	Product #
Concanavalin A from Canavalia ensiformis (Jack bean) Type IV-S, γ-irradiated, lyophilized powder, cell culture tested	Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca²⁺ and Mn²⁺ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.	C0412
Concanavalin A from Canavalia ensiformis (Jack bean) biotin conjugate, Type IV, lyophilized powder	Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca²⁺ and Mn²⁺ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.	C2272
Concanavalin A from Canavalia ensiformis (Jack bean) Type IV, lyophilized powder	Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca²⁺ and Mn²⁺ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.	C2010
Concanavalin A from Canavalia ensiformis (Jack bean) Type IV-S, lyophilized powder, aseptically processed, cell culture tested	Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca²⁺ and Mn²⁺ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.	C5275
Concanavalin A from Canavalia ensiformis (Jack bean) Type VI, lyophilized powder	Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca²⁺ and Mn²⁺ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.	L7647
Concanavalin A from Canavalia ensiformis (Jack bean) FITC conjugate, Type IV, lyophilized powder	Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca²⁺ and Mn²⁺ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.	C7642
Lectin from Bandeiraea simplicifolia (Griffonia simplicifolia) Isolectin B₄ (BSI-B₄), biotin conjugate, lyophilized powder	BS-I has a major affinity for terminal α-D-galactosyl residues with a secondary affinity for terminal N-acetyl-α-D-galactosaminyl residues.¹	L2140
Lectin from Bandeiraea simplicifolia (Griffonia simplicifolia) Isolectin B₄ (BSI-B₄), FITC conjugate, lyophilized powder	BS-I has a major affinity for terminal α-D-galactosyl residues with a secondary affinity for terminal N-acetyl-α-D-galactosaminyl residues.¹	L2895
Lectin from Bandeiraea simplicifolia (Griffonia simplicifolia) Isolectin B₄ (BSI-B₄), peroxidase conjugate, lyophilized powder	BS-I has a major affinity for terminal α-D-galactosyl residues with a secondary affinity for terminal N-acetyl-α-D-galactosaminyl residues.¹	L5391
Lectin from Bandeiraea simplicifolia (Griffonia simplicifolia) Isolectin B₄ (BSI-B₄), lyophilized powder	BS-I has a major affinity for terminal α-D-galactosyl residues with a secondary affinity for terminal N-acetyl-α-D-galactosaminyl residues.¹	L3019
Lectin from Phaseolus vulgaris (red kidney bean) Phytohemagglutinin PHA-P, purified by affinity chromatography, lyophilized powder	PHA consists of two molecular species, an erythroagglutinin (PHA-E) which has low mitogenic activity and high erythroagglutinin activity, and leucoagglutinin (PHA-L) which has high mitogenic and leucoagglutinating activity, but very low erythroagglutinating activity.^1,² PHA-E is not blood group specific, but agglutination can be inhibited by certain oligosaccharides.³ PHA-P is the protein form of PHA prior to separation and purification of erythroagglutinin and leucoagglutinin.⁴ PHA-M is the mucoprotein form.⁴ Conjugates are prepared from the corresponding purified lectins.	L9017
Lectin from Phaseolus vulgaris (red kidney bean) Phytohemagglutinin PHA-M, cell culture tested, lyophilized powder	PHA consists of two molecular species, an erythroagglutinin (PHA-E) which has low mitogenic activity and high erythroagglutinin activity, and leucoagglutinin (PHA-L) which has high mitogenic and leucoagglutinating activity, but very low erythroagglutinating activity.^1,² PHA-E is not blood group specific, but agglutination can be inhibited by certain oligosaccharides.³ PHA-P is the protein form of PHA prior to separation and purification of erythroagglutinin and leucoagglutinin.⁴ PHA-M is the mucoprotein form.⁴ Conjugates are prepared from the corresponding purified lectins.	L8902
Lectin from Phaseolus vulgaris (red kidney bean) Leucoagglutinin PHA-L, lyophilized powder	PHA consists of two molecular species, an erythroagglutinin (PHA-E) which has low mitogenic activity and high erythroagglutinin activity, and leucoagglutinin (PHA-L) which has high mitogenic and leucoagglutinating activity, but very low erythroagglutinating activity.^1,² PHA-E is not blood group specific, but agglutination can be inhibited by certain oligosaccharides.³ PHA-P is the protein form of PHA prior to separation and purification of erythroagglutinin and leucoagglutinin.⁴ PHA-M is the mucoprotein form.⁴ Conjugates are prepared from the corresponding purified lectins.	L2769
Lectin from Phaseolus vulgaris (red kidney bean) Phytohemagglutinin PHA-M, lyophilized powder	PHA consists of two molecular species, an erythroagglutinin (PHA-E) which has low mitogenic activity and high erythroagglutinin activity, and leucoagglutinin (PHA-L) which has high mitogenic and leucoagglutinating activity, but very low erythroagglutinating activity.^1,² PHA-E is not blood group specific, but agglutination can be inhibited by certain oligosaccharides.³ PHA-P is the protein form of PHA prior to separation and purification of erythroagglutinin and leucoagglutinin.⁴ PHA-M is the mucoprotein form.⁴ Conjugates are prepared from the corresponding purified lectins.	L2646
Lectin from Phaseolus vulgaris (red kidney bean) Leucoagglutinin PHA-L, cell culture tested, lyophilized powder	PHA consists of two molecular species, an erythroagglutinin (PHA-E) which has low mitogenic activity and high erythroagglutinin activity, and leucoagglutinin (PHA-L) which has high mitogenic and leucoagglutinating activity, but very low erythroagglutinating activity.^1,² PHA-E is not blood group specific, but agglutination can be inhibited by certain oligosaccharides.³ PHA-P is the protein form of PHA prior to separation and purification of erythroagglutinin and leucoagglutinin.⁴ PHA-M is the mucoprotein form.⁴ Conjugates are prepared from the corresponding purified lectins.	L4144
Lectin from Phytolacca americana (pokeweed) cell culture tested, lyophilized powder	PWM is extracted from pokeweed roots. This protein has hemagglutinating, leukoagglutinating, and mitogenic properties.¹ PWM is not blood group specific, but has affinity for N-acetyl-β-D-glucosamine oligomers.¹	L8777
Lectin from Phytolacca americana (pokeweed) lyophilized powder	PWM is extracted from pokeweed roots. This protein has hemagglutinating, leukoagglutinating, and mitogenic properties.¹ PWM is not blood group specific, but has affinity for N-acetyl-β-D-glucosamine oligomers.¹	L9379
Lectin from Pisum sativum (pea) FITC conjugate, lyophilized powder	PSA is not blood group specific, but has an affinity for terminal α-D-mannosyl residues. PSA is a mitogen similar to concanavalin A.	L0770
Lectin from Triticum vulgaris (wheat) peroxidase conjugate, lyophilized powder	WGA is not blood group specific but has an affinity for N-acetyl-β-D-glucosaminyl residues and N-acetyl-β-D-glucosamine oligomers. WGA contains no protein-bound carbohydrate.	L3892
Lectin from Triticum vulgaris (wheat) lyophilized powder	WGA is not blood group specific but has an affinity for N-acetyl-β-D-glucosaminyl residues and N-acetyl-β-D-glucosamine oligomers. WGA contains no protein-bound carbohydrate.	L9640
Lectin from Triticum vulgaris (wheat) biotin conjugate, lyophilized powder	WGA is not blood group specific but has an affinity for N-acetyl-β-D-glucosaminyl residues and N-acetyl-β-D-glucosamine oligomers. WGA contains no protein-bound carbohydrate.	L5142
Lectin from Triticum vulgaris (wheat) peroxidase conjugate, lyophilized powder	WGA is not blood group specific but has an affinity for N-acetyl-β-D-glucosaminyl residues and N-acetyl-β-D-glucosamine oligomers. WGA contains no protein-bound carbohydrate.	L7017
Lectin from Triticum vulgaris (wheat) FITC conjugate, lyophilized powder	WGA is not blood group specific but has an affinity for N-acetyl-β-D-glucosaminyl residues and N-acetyl-β-D-glucosamine oligomers. WGA contains no protein-bound carbohydrate.	L4895
Lectin from Ulex europaeus (gorse, furze) FITC conjugate, lyophilized powder	Ulex europaeus agglutinin has anti-H blood group specificity. There are two types of lectin: UEA I has an affinity for L-fucose and UEA II has an affinity for N,N′-diacetylchitobiose. The mol. wt. of UEA I was initially found to be 170,000 daltons. Later reports indicate that UEA I may form aggregates at neutral and basic pH and that the correct mol. wt. is 68,000 daltons.	L9006
Lectin from Ulex europaeus (gorse, furze) biotin conjugate, lyophilized powder	Ulex europaeus agglutinin has anti-H blood group specificity. There are two types of lectin: UEA I has an affinity for L-fucose and UEA II has an affinity for N,N′-diacetylchitobiose. The mol. wt. of UEA I was initially found to be 170,000 daltons. Later reports indicate that UEA I may form aggregates at neutral and basic pH and that the correct mol. wt. is 68,000 daltons.	L8262
Lectin from Ulex europaeus (gorse, furze) lyophilized powder	Ulex europaeus agglutinin has anti-H blood group specificity. There are two types of lectin: UEA I has an affinity for L-fucose and UEA II has an affinity for N,N′-diacetylchitobiose. The mol. wt. of UEA I was initially found to be 170,000 daltons. Later reports indicate that UEA I may form aggregates at neutral and basic pH and that the correct mol. wt. is 68,000 daltons.	L5505
Anti-Lectin, Canavalia ensiformis antibody produced in rabbit fractionated antiserum, lyophilized powder		C7401
Anti-Lectin, Ulex europaeus-I antibody produced in rabbit fractionated antiserum, liquid		U4754
Ricin A chain from Ricinus communis (castor bean) deglycosylated, buffered aqueous glycerol solution	Ricin A chain inactivates the 60 S ribosomal subunit of eukaryotic cells, inhibiting protein synthesis. This toxic activity is independent of the presence of the B chain of ricin. The carbohydrate moiety of Ricin A chain has been modified using a metaperiodate-cyanoborohydride mixture. The product still inhibits protein synthesis in cell-free systems, and its removal from the blood stream by the liver is markedly decreased. Immunotoxins prepared from deglycosylated Ricin A chain will therefore be more effective in killing target cells.	L4022

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