GABAergics

Schematic Representation of the GABA_B Receptor
Representation of the GABA_B receptor heterodimer which is composed of two, seven transmembrane-spanning units which are linked by their C‑termini. The apparent ligand binding domains are on the extracellular surface of R1 and R2. Activation of the heterodimer modulates adenylyl cyclase activity via G proteins that, in addition, influence K⁺ and Ca²⁺ conductances.