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CAS Number
Product #
16,17-Epoxy-21-
acetoxypregnenolone ≥98%
28444-97-5
E4625
16-Dehydropregnenolone acetate ≥95%
979-02-2
D4875
16-Methylene-17α-
hydroxypregnenolone 3-acetate
15369-66-1
M8626
17α-Hydroxypregnenolone
387-79-1
H5002
3α,12α-Dihydroxy-
5β-pregnan-20-one 3,12-diacetate
15991-93-2
P5902
3α,21-Dihydroxy-5α-
pregnan-20-one ≥95%
Positive allosteric modulator of GABA
A
receptors.
567-02-2
P2016
5α-Pregnan-3α-ol-
11,20-dione powder, ≥98% (TLC)
Synthetic steroid compound alphaxalone (AFX) - 5α-Pregnan-3α-ol-11,20-dione- is a neurosteroid that directly activates and potentiates GABA
A
receptor-activated membrane current (IGABA). It acts as a positive allosteric modulator of the GABA
A
receptor; anesthetic. The alpha subunit subtype of GABA
A
determines the efficacy, but not the potency, of AFX neuroactive steroid to potentiate IGABA.
P5052
5α-Pregnan-3α-ol-
20-one solid
Positive allosteric modulator of GABA
A
chloride channel.
516-54-1
P8887
5α-Pregnan-3β-ol-
20-one 3β-acetate ≥98%
906-83-2
P8004
CGP-13501 ≥98% (HPLC), solid
Positive allosteric modulator of GABA
B
receptors.
C0987
CGP-7930 >98% (HPLC), solid
Positive allosteric modulator of GABA
B
receptors.
C0862
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate ≥98%, powder
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate is a negative allosteric modulator of GABA
A
receptors.
78590-17-7
D5297
GS39783 ≥98% (HPLC), powder
Positive allosteric modulator of GABA
B
receptors
G5919
Guvacine hydrochloride ≥97% (NMR), solid
GABA uptake inhibitor.
6027-91-4
G007
NCS-356 sodium salt hydrate solid, ≥98% (HPLC)
γ-Hydroxybutyrate (GHB) receptor agonist.
430440-66-7
N4034
NCS-382 hydrate solid, ≥98% (HPLC)
γ-Hydroxybutyrate (GHB) receptor antagonist; anticonvulsant.
N4159
NO-711 hydrochloride solid, ≥98% (HPLC)
Potent and selective GABA uptake inhibitor that crosses the blood-brain barrier.
145645-62-1
N142
Nipecotic acid 98%
498-95-3
211672
Pregnenolone sulfate sodium salt
Neurosteroid that antagonizes the GABA
A
receptor chloride channel.
P162
γ-Hydroxybutyric acid sodium salt
Endogenous GABA analog that induces absence-like seizures. It blocks dopamine release by blocking impulse flow in dopaminergic neurons.
502-85-2
H3635
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