Product Catalog → Cell Biology → Cell Signaling and Neuroscience → Gene Regulation and Expression → Transcription Factors

Print Preview

Transcription Factors

Reset Table

Description	Biochem/physiol Actions	Product #
ATF-2 human ≥90% (SDS-PAGE), recombinant, expressed in Escherichia coli, lyophilized powder	ATF-2 is a member of the leucine zipper protein family which regulates gene transcription by interacting with ATF/cAMP-response elements of genes. The transcriptional activity of ATF-2 is stimulated by phosphorylation of the amino acid residues threonine 69 and threonine 71, carried out by stress activated protein kinases (SAPKs) including JNK and p38 MAP kinase.	A2353
EGR-1 Protein human recombinant, expressed in Sf9 cells	EGR (Early Growth Response) proteins represent a family of transcription factors involved in cell cycle regulation. They contain three, nearly identical DNA-binding zinc finger regions, each possessing a unique flanking region. EGR-1, -2, -3, and -4, bind the EGR-consensus sequence GCG T/GGG GCG, however the individual proteins show differing binding affinities.	E5777
EGR-3 Protein human recombinant, expressed in Sf9 cells	EGR (Early Growth Response) proteins represent a family of transcription factors involved in cell cycle regulation. They contain three, nearly identical DNA-binding zinc finger regions, each possessing a unique flanking region. EGR-1, -2, -3, and -4, bind the EGR-consensus sequence GCG T/GGG GCG, however the individual proteins show differing binding affinities.	E3527
HMG-1 human lyophilized powder, ≥90% (SDS-PAGE), Histidine-tagged, recombinant, expressed in Escherichia coli	HMG-1, a prevalent non-histone chromatin component, is a non-sequence specific DNA binding protein. It participates in the regulation of chromatin structure as well as being involved (either as a positive or negative factor) with various aspects of DNA replication, transcription, repair and ligation. In addition, HMG-1 has been identified as a membrane associated protein termed "amphoterin" that mediates neurite outgrowth, tumor outgrowth and metastasis and participates in plasminogen activation. It is also recognized as a late mediator of endotoxin lethality in mice. HMG-1 is a highly conserved protein with more than 95% amino acid identity between rodent and human.	H4652
c-Jun human 40-50% (SDS-PAGE), recombinant, expressed in Escherichia coli, truncated human c-Jun sequence-GST fusion protein 1-169-GST, soluble	Substrate for SAPK1/JNK2. Purified protein transcription factor which binds the AP1 gene to activate transcription.	C5859
NFκB (p50) Control Peptide human solution		N6534
NFκB (p65) Control Peptide human ~1 mg/mL, buffered aqueous solution		N6659
NFκB (c-Rel) Control Peptide ~1 mg/mL, buffered aqueous solution		N6409
Oltipraz ≥98% (HPLC), powder	Oltipraz is an activator of Nrf2. Nrf2 (NF-E2-related factor 2) is a transcription factor that binds to antioxidant response elements (AREs) and activates these genes. Oltipraz activates Nrf2 and subsequently elevates expression of the detoxification genes encoding anti-oxidant and multidrug resistance-associated proteins to mediate its chemopreventive efficacy.	O9389
TFIIB human ~5 units/μL, recombinant, expressed in Escherichia coli, solution	General transcription factor for RNA Polymerase II.	T8819

Copyrights © 2008 Sigma-Aldrich Co. All Rights Reserved. Reproduction of any materials from the site is strictly forbidden without permission. Sigma-Aldrich brand products are sold exclusively through Sigma-Aldrich, Inc.