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Description
Biochem/physiol Actions
CAS Number
Product #
3-Nitropropionic acid ≥97%
Excitotoxin shown to cause brain lesions similar to those of Huntington's disease.
504-88-1
N5636
D
-Glutamine ≥98% (TLC)
5959-95-5
G9003
DL
-
threo
-
β-Hydroxyaspartic acid
Glutamate transport inhibitor.
4294-45-5
H2775
L
-Cysteinesulfinic acid
Putative excitatory amino acid neurotransmitter
1115-65-7
C4418
L
-Glutamine
ReagentPlus
®
, ≥99% (TLC)
L
-glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.
56-85-9
G3126
L
-Methionine sulfoximine
Increases ornithine decarboxylase activity, and decreases the survival rate in a model of transient cerebral ischemia. Inhibits glutamine synthetase activity, and increases the release of glutamic acid.
15985-39-4
M5379
L
-
trans
-
Pyrrolidine-2,4-dicarboxylic acid ≥98%
Selective inhibitor of glutamate uptake
64769-66-0
P7575
Chicago Sky Blue 6B powder
Large organic acid, structurally related to glutamate, that is a potent and efficient competitive inhibitor of vesicular glutamate uptake.
2610-05-1
C8679
Fenobam ≥98% (HPLC), solid
Fenobam is a potent, selective, noncompetitive glutamate mGluR5 receptor antagonist. Fenobam displays inverse agonist properties; blocks mGluR
5
constitutive activity
in vitro
(IC
50
= 87 nM, slightly weaker than MPEP). Fenobam acts at an allosteric modulatory site shared with MPEP and binds the mGlu
5
receptor with K
d
values of 54 and 31 nM for rat and human receptors, respectively. Fenobam belongs to a structurally different class than MPEP; devoid of GABAergic activity and thus typical benzodiazepine-like side effects; displays anxiolytic activity.
57653-26-6
F0430
Ibotenic acid ~95%, solid
Non-selective agonist with preference for NMDA glutamate receptors; neurotoxin; neuroexcitatory amino acid originally isolated from
Amanita
species.
2552-55-8
I2765
MPPG ≥97% (NMR), solid
Group III/II metabotropic glutamate (mGluR) receptor antagonist
169209-65-8
M1694
NS 521 oxalate solid
Novel benzimidazolone neuroprotective agent.
198969-52-7
N7904
Putrescine dihydrochloride ≥98% (TLC)
Binds to the polyamine modulatory site of the NMDA receptor and potentiates NMDA-induced currents; precursor of spermidine.
333-93-7
P7505
Riluzole solid
Glutamate release inhibitor; anticonvulsant
1744-22-5
R116
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