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NMDA Antagonists

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Image	Description	Biochem/physiol Actions	CAS Number	Product #
	(−)-MK-801 hydrogen maleate solid	Less active enantiomer of (+)-MK-801 hydrogen maleate	77086-19-2	M108
	(±)-2-Amino-4-phosphonobutyric acid solid	NMDA glutamate receptor antagonist.	20263-07-4	A1910
	(±)-CPP solid	Potent and selective NMDA glutamate receptor antagonist; anticonvulsant.	100828-16-8	C104
	(±)-Ketamine hydrochloride solid	Selective NMDA glutamate receptor antagonist; veterinary anesthetic.	1867-66-9	K2753
	(+)-MK-801 hydrogen maleate solid	Highly potent and selective non-competitive NMDA glutamate receptor antagonist that acts at the NMDA receptor-operated ion channel as an open channel blocker. Inhibits behavioral sensitization to psychostimulants and ethanol.	77086-22-7	M107
	5,7-Dichlorokynurenic acid monohydrate solid, ≥98% (HPLC)	Potent excitatory amino acid receptor antagonist; active at the strychnine-insensitive glycine binding site of the NMDA glutamate receptor.	190908-40-8	D138
	6,7-Dichloroquinoxaline-2,3-dione	Antagonist at the NMDA glutamate receptor glycine site.	25983-13-5	D133
	D(−)-2-Amino-5-phosphonopentanoic acid	Potent and selective antagonist for NMDA receptors. Anticonvulsant; potent and selective NMDA receptor antagonist; active enantiomer of 2-amino-5-phosphonopentanoic acid.	79055-68-8	A8054
	D(−)-2-Amino-7-phosphonoheptanoic acid solid	Selective NMDA glutamate receptor antagonist; anticonvulsant; active enantiomer of 2-amino-7-phosphonoheptanoic acid.	81338-23-0	A167
	DL-2-Amino-5-phosphonopentanoic acid solid	Anticonvulsant; potent and selective NMDA receptor antagonist.	76326-31-3	A5282
	DL-2-Amino-7-phosphonoheptanoic acid ~95%	Selective NMDA glutamate receptor antagonist; anticonvulsant.	85797-13-3	A5157
	Arcaine sulfate salt	Potent antagonist at the polyamine site of the NMDA glutamate receptor.	14923-17-2	A0384
	CNS-1102 >98% (HPLC), solid	Noncompetitive NMDA glutamate receptor antagonist.		C4238
	DMeOB ≥98% (HPLC), solid	Negative allosteric modulator at the metabotropic glutamate receptor mGluR₅.	40252-74-2	D6317
	Dextromethorphan hydrobromide monohydrate Sigma Reference Standard		6700-34-1	D1053
	Dextromethorphan hydrobromide meets USP testing specifications		6700-34-1	D9684
	Dextrorphan tartrate solid	Noncompetitive NMDA glutamate receptor antagonist that attenuates glutamate neurotoxicity in cortical cell cultures.	143-98-6	D127
	Ifenprodil (+)-tartrate salt	NMDA antagonist acting at the polyamine site; neuroprotective agent; α-adrenergic central and peripheral vasodilator; α₂ adrenergic receptor ligand.	23210-58-4	I2892
	L-701,324 ≥98% (HPLC), solid	L-701,324 is a high affinity, selective antagonist at the glycine site of the NMDA glutamate receptor. L-701,324 is a potent, active anticonvulsant with a reduced propensity to activate mesolimbic dopaminergic systems in rodents.	142326-59-8	L0258
	MDL 105,519 solid	High affinity NMDA glutamate receptor antagonist at the glycine site.		M216
	Memantine hydrochloride ≥98% (GC)	Low-affinity NMDA glutamate receptor antagonist; stimulates dopamine release.	41100-52-1	M9292
	N-(3,3-Diphenylpropyl)glycinamide >98% (HPLC), solid	NMDA glutamate receptor open channel blocker.		D8816
	Pentamidine isethionate salt powder	Neuroprotective; inhibits constitutive nitric oxide synthase in the brain; NMDA glutamate receptor antagonist.	140-64-7	P0547
	R(+)-HA-966 solid	Antagonist of the strychnine-insensitive glycine modulatory site associated with the NMDA receptor. More active enantiomer of (±)-HA-966.	123931-04-4	H130
	Ro 25-6981 hydrochloride ≥98% (HPLC), solid	Potent and selective antagonist of NMDA glutamate receptors containing the NR2B subunit.	919289-58-0	R7150
	Ro 8-4304 solid	NR2B-selective, noncompetitive NMDA glutamate receptor antagonist		R8900
	S-(+)-Ketamine hydrochloride	Selective NMDA glutamate receptor antagonist.	33795-24-3	K1884
	[Glu^3,4,7,10,14]-Conantokin G >90% (HPLC)	Highly conserved polypeptide NMDA glutamate receptor antagonist; acts through a potent noncompetitive inhibition of polyamine responses; approximately 7-fold more potent than spermine		C1733
	d-3-Methoxy-N-methylmorphinan hydrobromide ≥99 (TLC)	Allosteric antagonist at NMDA-controlled ion channels; antagonist at voltage-dependent channels	6700-34-1	D2531

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